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公开(公告)号：KR1020160079560A
公开(公告)日：2016-07-06
申请号：KR1020140191090
申请日：2014-12-26
Applicant: 강원대학교산학협력단
IPC: C07D207/48 , C07D207/46
CPC classification number: C07D207/48 , C07D207/46
Abstract: 본발명은천연물과생리활성물질에사용되거나원료물질또는중간체로사용가능한신규한피롤유도체및 이의제조방법을제공한다.
Abstract translation: 本发明涉及由化学式1表示的吡咯衍生物及其制备方法。 吡咯衍生物用于天然材料和生物活性材料，可用于原料或中间体。
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公开(公告)号：KR1020140128165A
公开(公告)日：2014-11-05
申请号：KR1020130047014
申请日：2013-04-26
Applicant: 강원대학교산학협력단
Abstract: 본발명은신규한엔올실릴이서유도체및 이의제조방법에관한것으로본 발명의신규한엔올실릴이서유도체는탄소-탄소결합형성에매우중요한화합물로사용될수 있으며, 본발명에따른엔올실릴이서유도체의제조방법은온화한조건에서간단한공정으로높은수율로엔올실릴이서유도체를얻을수 있다.
Abstract translation: 本发明涉及新型烯醇甲硅烷基醚衍生物及其制造方法。 本发明的新型烯醇甲硅烷基醚衍生物能够用作碳 - 碳键形成重要的化合物。 根据本发明的烯醇甲硅烷基醚衍生物的制造方法能够在温和条件下以简单的方法以高产率获得烯醇甲硅烷基醚衍生物。
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公开(公告)号：KR101448585B1
公开(公告)日：2014-10-13
申请号：KR1020140053272
申请日：2014-05-02
Applicant: 강원대학교산학협력단
IPC: C07F9/6571 , C07F9/6584 , C07B63/04
CPC classification number: C07F9/657181 , C07F9/65844
Abstract: The present invention relates to a novel dihydro-1H-phosphole 1-oxide derivative and a preparation method thereof. More particularly, the dihydro-1H-phosphole 1-oxide derivative of the present invention includes 1,3-dihydro-1H-2,1-oxaphosphole 1-oxide derivative and 2,3-dihydro-1H-2,1-azaphosphole 1-oxide derivative. The dihydro-1H-phosphole 1-oxide derivative according to the present invention has pharmacological activity and biological activity and may be used as agricultural chemicals such as herbicide and as an important intermediate for synthesizing diverse medicines. In addition, in the preparation method of the dihydro-1H-phosphole 1-oxide derivative according to the present invention, diverse phosphinine oxide derivatives may be prepared with high yield by a simple synthetic process through reacting a phosphinic derivative and a vinyl derivative in the presence of a rhodium (Rh) catalyst, an oxidizing agent and a base.
Abstract translation: 本发明涉及一种新的二氢-1H-磷酸1-氧化物衍生物及其制备方法。 更具体地说，本发明的二氢-1H-磷酸1-氧化物衍生物包括1,3-二氢-1H-2,1-氧代磷杂环1-氧化物衍生物和2,3-二氢-1H-2,1-氮杂孔1 - 氧化物衍生物。 本发明的二氢-1H-磷酸1-氧化物衍生物具有药理活性和生物活性，可用作除草剂等农药，作为合成多种药物的重要中间体。 此外，在本发明的二氢-1H-磷酸1-氧化物衍生物的制备方法中，可以通过简单的合成方法通过使次膦酸衍生物和乙烯基衍生物在 存在铑（Rh）催化剂，氧化剂和碱。
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4.发明授权
公开(公告)号：KR101663064B1
公开(公告)日：2016-10-06
申请号：KR1020140187193
申请日：2014-12-23
Applicant: 강원대학교산학협력단
IPC: C07C311/16 , C07C303/36 , C07C303/40
Abstract: 본발명은하기화학식 1로표시되는새로운 N-(2-(아줄렌-1-일)-2-치환된바이닐)-설폰아마이드유도체및 이의제조방법에관한것이다. [화학식 1]본발명에따른-(2-(아줄렌-1-일)-2-치환된바이닐)-설폰아마이드유도체의제조방법은로듐(lI) 촉매하에설폰기를포함하는트리아졸유도체와의반응을통해부산물로써질소기체만을배출한다는장점을지닐뿐만아니라, 높은수율로-(2-(아줄렌-1-일)-2-치환된바이닐)-설폰아마이드유도체를합성한다.
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5.发明公开
公开(公告)号：KR1020160076753A
公开(公告)日：2016-07-01
申请号：KR1020140187193
申请日：2014-12-23
Applicant: 강원대학교산학협력단
IPC: C07C311/16 , C07C303/36 , C07C303/40
CPC classification number: C07C311/16 , C07C303/36 , C07C303/40 , C07C2523/46 , C07C2523/72
Abstract: 본발명은하기화학식 1로표시되는새로운 N-(2-(아줄렌-1-일)-2-치환된바이닐)-설폰아마이드유도체및 이의제조방법에관한것이다. [화학식 1]본발명에따른-(2-(아줄렌-1-일)-2-치환된바이닐)-설폰아마이드유도체의제조방법은로듐(lI) 촉매하에설폰기를포함하는트리아졸유도체와의반응을통해부산물로써질소기체만을배출한다는장점을지닐뿐만아니라, 높은수율로-(2-(아줄렌-1-일)-2-치환된바이닐)-설폰아마이드유도체를합성한다.
Abstract translation: 本发明涉及一种新型的N-（2-（薁-1-基）-2-取代的乙烯基） - 磺酰胺衍生物及其制备方法。 根据本发明的制备N-（2-（薁-1-基）-2-取代的乙烯基） - 磺酰胺衍生物的方法具有的优点是仅通过与砜反应产生作为副产物的氮气 基团的三唑衍生物在铑（II）催化剂存在下进行。 此外，该方法以高产率提供了N-（2-（薁-1-基）-2-取代的乙烯基） - 磺酰胺衍生物。
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Patent Agency Ranking
公开(公告)号：KR101467251B1
公开(公告)日：2014-12-01
申请号：KR1020130011135
申请日：2013-01-31
Applicant: 강원대학교산학협력단
Abstract: 본발명은하기화학식 1로표시되는인아인유도체및 이의제조방법에관한것이다. 보다상세하게는, 본발명은바이닐프로파질할라이드유도체와인듐(Indium; In)을반응시켜인-시츄로얻어지는유기인듐시약과할라이드유도체를팔라듐촉매존재하에서교차짝지움반응시켜높은수율로인아인유도체를선택적으로제조하는방법및 제조된신규한인아인유도체에관한것이다. [화학식 1]상기화학식 1에서, R및 R는각각발명의상세한설명에서정의한바와같다.
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公开(公告)号：KR101859928B1
公开(公告)日：2018-05-21
申请号：KR1020170071562
申请日：2017-06-08
Applicant: 강원대학교산학협력단
IPC: C07D471/04 , A61K31/437 , A61K31/519 , A61K31/36 , C07D487/04
CPC classification number: C07D471/04 , B01J31/04 , A61K31/36 , A61K31/437 , A61K31/519 , C07D487/04
Abstract: 본발명은이미다조[1,2-a]피리딘-3-카복실레이트유도체및 이의제조방법에관한것으로, 보다상세하게는구리(II) 촉매존재하에α-다이아조옥심에테르유도체및 피리딘유도체를아자-[3+2]고리첨가반응시켜이미다조[1,2-a]피리딘-3-카복실레이트유도체를효율적으로제조하는방법및 이에따라제조된이미다조[1,2-a]피리딘-3-카복실레이트유도체에관한것이다.
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公开(公告)号：KR101532564B1
公开(公告)日：2015-06-30
申请号：KR1020130047014
申请日：2013-04-26
Applicant: 강원대학교산학협력단
Abstract: 본발명은신규한엔올실릴이서유도체및 이의제조방법에관한것으로본 발명의신규한엔올실릴이서유도체는탄소-탄소결합형성에매우중요한화합물로사용될수 있으며, 본발명에따른엔올실릴이서유도체의제조방법은온화한조건에서간단한공정으로높은수율로엔올실릴이서유도체를얻을수 있다.
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公开(公告)号：KR1020140098468A
公开(公告)日：2014-08-08
申请号：KR1020130011146
申请日：2013-01-31
Applicant: 강원대학교산학협력단
IPC: C07C315/06 , C07C317/10 , C07B61/00
Abstract: The present invention relates a method for manufacturing alkenyl triflate derivatives represented as chemical formula 1. The manufacturing method of the present invention has benefits not only to reduce reaction byproducts through addition reaction of tribonding derivatives and trifluoro methane sulfonate but also to streamline reaction steps to one step and to manufacture alkenyl triflate derivatives in high yield.
Abstract translation: 本发明涉及一种化学式1表示的三氟甲磺酸烯基酯衍生物的制造方法。本发明的制造方法不仅有利于通过加入各种衍生物和三氟甲磺酸盐的反应来还原反应副产物，还有助于将反应步骤简化为一 并以高产率制备链烯基三氟甲磺酸酯衍生物。
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公开(公告)号：KR1020140098464A
公开(公告)日：2014-08-08
申请号：KR1020130011135
申请日：2013-01-31
Applicant: 강원대학교산학협력단
Abstract: The present invention relates to an enyne derivative represented by chemical formula 1 and a manufacturing method thereof and, more specifically, to a method for selectively manufacturing an enyne derivative with high yield by performing cross coupling reactions on halide derivatives and organic indium reagents produced in situ by making vinyl propargyl halide derivatives react with indium (In) under presence of palladium catalysts and to a novel enyne derivative manufactured by the method. (In chemical formula 1, R_1 and R_2 are the same as defined in the detailed prescription of the present invention.)
Abstract translation: 本发明涉及由化学式1表示的烯衍生物及其制备方法，更具体地说涉及通过对原位产生的卤化物衍生物和有机铟试剂进行交叉偶联反应来选择性地制备具有高收率的烯炔衍生物的方法 通过在钯催化剂的存在下使炔丙基卤衍生物与铟（In）反应，以及通过该方法制造的新型烯炔衍生物。 （在化学式1中，R 1和R 2与本发明的详细处方中定义相同）
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