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公开(公告)号：KR101521491B1
公开(公告)日：2015-05-21
申请号：KR1020120084110
申请日：2012-07-31
Applicant: 강원대학교산학협력단 , 서원대학교산학협력단 , 주식회사 세바바이오텍
Abstract: 본발명은커피(원두또는부산물) 발효물및 이의추출물을함유하는화장료조성물에관한것으로서, 보다구체적으로는가공되지않은커피원두자체또는대부분이소비되지않고폐기되는커피부산물을유산균주를이용하여발효한후 얻어진발효액과이의발효액을제외한나머지건체커피발효잔여물을에탄올추출하여얻어진커피발효잔여추출물을유효성분으로포함하는고기능성화장료조성물에관한것이다. 본발명의커피(원두또는부산물) 발효물및 이의추출물은천연물유래의소재로서피부에안정하면서도피부세포증식효과, 항산화효과, 보습효과, 주름개선효과, 피부미백효과및 항염효과를동시에나타낼수 있으므로, 이를유효성분으로포함하는본 발명의조성물은고기능성화장료조성물로서유용하게사용될수 있다. 또한본 발명의상기커피(원두또는부산물) 발효물및 이의추출물은단가가저렴한원두자체또는폐기되어버려지는커피부산물을활용하여간단한공정을통해제조될있으므로, 시간, 노력및 비용을절감할수 있는경제적인효과를가질뿐만아니라폐기물의재활용을통한친환경적인효과도기대할수 있다.
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公开(公告)号：KR1020140098503A
公开(公告)日：2014-08-08
申请号：KR1020130011257
申请日：2013-01-31
Applicant: 주식회사 세바바이오텍 , 서원대학교산학협력단 , 강원대학교산학협력단
Abstract: The present invention relates to a decompression-recirculation high-speed steaming device and a method for producing ginseng having an increased low-molecular ginsenosides content and, more specifically, to a method for producing the ginseng in which the content of the low-molecular ginsenosides such as Rh2, Rg2, Rg3, and CK is increased by inputting ginseng into the device of the present invention and steaming the inputted ginseng under a decompression condition. When steaming ginseng by using the decompression-recirculation high-speed steaming device of the present invention, an effect of rapidly producing red ginseng by effectively increasing the low-molecular ginsenosides (Rh2, Rg2, Rg3, and CK) contained in ginseng can be obtained and an effect of having a little content of benzopyrene that is a carcinogen by not going through a repetitive steaming step for a long time as in the past. Furthermore, when steaming ginseng by using the device of the present invention, a value of the ginseng can be increased by applying the method to cheap ginseng as a huge morphologic change of ginseng is not generated. Therefore, the decompression-recirculation high-speed steaming device and method for producing ginseng having the increased low-molecular ginsenosides content of the present invention can be usefully applied in not only medicine and medical supplies but also functional food and cosmetics.
Abstract translation: 本发明涉及一种减压 - 再循环高速蒸汽装置和一种生产具有增加的低分子人参皂甙含量的人参的方法，更具体地说，涉及一种生产人参的方法，其中低分子量人参皂苷的含量 通过将人参输入本发明的装置并在减压条件下蒸煮输入的人参，从而增加了Rh2，Rg2，Rg3和CK。 当通过使用本发明的减压 - 再循环高速蒸汽装置蒸人参时，可以获得通过有效增加人参中所含的低分子量人参皂甙（Rh2，Rg2，Rg3和CK）迅速生产红参的效果 并且通过与过去不经历长时间的重复蒸汽步骤，具有作为致癌物的苯并芘含量少的效果。 此外，当通过使用本发明的装置蒸制人参时，通过将该方法应用于廉价人参可以提高人参的价值，因为不会产生人参的巨大形态变化。 因此，本发明的具有增加的低分子量人参皂甙含量的人参的减压 - 再循环高速蒸汽装置和制造方法不仅可用于医药和医疗用品，还可用于功能性食品和化妆品。
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公开(公告)号：KR1020140027614A
公开(公告)日：2014-03-07
申请号：KR1020120085913
申请日：2012-08-06
Applicant: 강원대학교산학협력단 , 서원대학교산학협력단 , 주식회사 세바바이오텍
Abstract: The present invention relates to a manufacturing method of a functional coffee drink composition including fermented coffee products (coffee beans or by-products) and an extract thereof, and, more specifically, to a manufacturing method of a functional coffee drink composition including fermented liquid and fermented coffee residual extract, and a functional coffee drink composition manufactured thereby, wherein the fermented liquid is obtained by fermenting unprocessed coffee beans or coffee by-products, which are mostly discarded without being consumed, by using lactobacillus, and the fermented coffee residual extract is obtained by extracting the dried fermented coffee residue besides the fermented liquid, with ethanol. As the manufacturing method of the present invention is able to enhance elution of chlorogenic acid in the coffee through a simple process, the composition of the present invention manufactured through the method contains a large quantity of chlorogenic acid having a lipoperoxide production suppressing effect, cholesterol biosynthesis inhibition effect, an anti-oxidation activity, an anti-inflammatory effect and an anti-cancer effect, enabling the composition to be used as a functional coffee drink composition. Further, the manufacturing method of the present invention utilizes coffee beans, of which the unit price is cheap, or discarded coffee by-products to create novel health materials having functionalities, to provide an eco-friendly effect through the recycling of waste. [Reference numerals] (AA) Free radical elimination rate (%); (BB) Concentration (쨉m); (CC) Hydrothermal extract of coffee beans (Comparative example); (DD) Hydrothermal extract of coffee by-product (Comparative example)
Abstract translation: 本发明涉及一种包含发酵咖啡产品（咖啡豆或副产物）及其提取物的功能性咖啡饮料组合物的制造方法，更具体地，涉及包含发酵液体的功能性咖啡饮料组合物的制造方法， 发酵咖啡残余提取物和由此制造的功能性咖啡饮料组合物，其中，所述发酵液体通过使用乳杆菌发酵未处理大部分被废弃而未被消耗的未加工咖啡豆或咖啡副产物而获得，所述发酵咖啡残余提取物为 通过用乙醇萃取除了发酵液之外的干燥的发酵咖啡残渣获得。 由于本发明的制造方法能够通过简单的方法提高咖啡中的绿原酸的洗脱，所以通过该方法制造的本发明的组合物含有大量具有脂肪过氧化物产生抑制作用的绿原酸，胆固醇生物合成 抑制效果，抗氧化活性，抗炎作用和抗癌作用，使得该组合物可用作功能性咖啡饮料组合物。 此外，本发明的制造方法利用单价廉价的咖啡豆或者丢弃的咖啡副产品来制造具有功能的新型健康材料，通过废物的再循环来提供环保效果。 （标号）（AA）自由基消除率（％）; （BB）浓度（쨉m）; （CC）咖啡豆水热提取物（比较例）; （DD）咖啡副产物水热提取物（比较例）
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公开(公告)号：KR1020140013800A
公开(公告)日：2014-02-05
申请号：KR1020120082332
申请日：2012-07-27
Applicant: 강원대학교산학협력단 , 서원대학교산학협력단 , 주식회사 세바바이오텍
IPC: A23L19/00 , A23L1/30 , A61K36/258 , A61K8/97
CPC classification number: A61K36/258 , A23L33/105 , A61K8/97 , A61K36/344 , A61K36/539 , A61K2236/39 , A61K2800/85 , A61Q19/00
Abstract: The present invention relates to a method for enhancing the content of bioactive substances of a natural substance using simultaneous middle temperature extraction and a fermentation process and more specifically, in the present invention, since natural substances are fermented at 45-70°C using Bacillus coagulans, which is an edible thermophilic bacterium, and extracted at the same time, the content of effective bioactive substances is enhanced compared to the content thereof obtained by traditional fermentation, and an economic effect can be increased as the entire time required for the process is shortened. Thus, the effective bioactive substances can be effectively extracted from natural substances which have undergone simultaneous middle temperature extraction and fermentation and can be used for manufacturing health functional foods, pharmaceutical products, and cosmetics.
Abstract translation: 本发明涉及使用同时中温提取和发酵方法提高天然物质生物活性物质含量的方法，更具体地说，在本发明中，由于天然物质在45-70℃下使用凝结芽孢杆菌 ，这是一种可食用的嗜热细菌，同时提取，与传统发酵得到的含量相比，有效生物活性物质的含量增加，并且缩短了整个过程所需的整个时间，可以提高经济效果 。 因此，有效的生物活性物质可以从经过同时中温提取和发酵的天然物质中有效提取，并可用于制造健康功能性食品，药品和化妆品。
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公开(公告)号：KR101149545B1
公开(公告)日：2012-05-29
申请号：KR1020100037816
申请日：2010-04-23
Applicant: 강원대학교산학협력단
IPC: A61K36/704 , A61K36/489 , A61K36/12 , A61P17/00
Abstract: 본 발명은 편축 , 구맥 , 해금사, 및 고삼으로 구성된 군으로부터 선택된 하나 이상의 식물 추출물을 유효성분으로 함유하는 피부 질환 예방 및 치료용 조성물에 관한 것으로, 화장품 및 의약품에 적용성을 갖고 있다.
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Patent Agency Ranking
公开(公告)号：KR1020120002517A
公开(公告)日：2012-01-05
申请号：KR1020110137572
申请日：2011-12-19
Applicant: 강원대학교산학협력단
IPC: A61K36/489 , A61K36/48 , A61K36/704 , A61P17/00
CPC classification number: A61K36/704 , A61K36/36 , A61K36/489 , Y10S514/859
Abstract: PURPOSE: A composition containing Sophora flavescens Aiton extract for preventing and treating dermatitis is provided to suppress propionibacterium acne. CONSTITUTION: A composition for preventing and treating dermatitis contains Sophora flavescens Aiton extract as an active ingredient. The daily dose of the extract is 10-5000mg a day. The composition is manufactured in the form of a solution, suspension, emulsion, paste, gel, cream, soap, surfactant-containing cleansing, oil, powder foundation, emulsion foundation, wax foundation, or spray.
Abstract translation: 目的：提供含有苦参皂甙的组合物，用于预防和治疗皮炎，以抑制丙酸杆菌。 构成：用于预防和治疗皮炎的组合物含有苦参皂甙提取物作为活性成分。 提取物的日剂量为每天10-5000mg。 该组合物以溶液，悬浮液，乳液，糊剂，凝胶，奶油，肥皂，含表面活性剂的清洁剂，油，粉底，乳液粉底，蜡基础或喷雾剂的形式制备。
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公开(公告)号：KR101430636B1
公开(公告)日：2014-08-18
申请号：KR1020120082283
申请日：2012-07-27
Applicant: 강원대학교산학협력단 , 서원대학교산학협력단 , 주식회사 세바바이오텍 , (주) 피엘코스메틱
Abstract: 본 발명은 인삼, 홍삼 및 산삼배양근으로부터 분리된 저분자 진세노사이드 Rh2 및 진세노사이드 Rg3를 함유하는 화장료 조성물에 관한 것으로서, 보다 구체적으로는 진세노사이드 Rh2 및 진세노사이드 Rg3를 2:8 ~ 4:6의 혼합비(w/w)로 포함하고, 진세노사이드 Rh2 및 진세노사이드 Rg3의 혼합물 총중량에 대해 고형분으로서 1~5중량%의 양으로 포함되었을 때, 아토피 피부염, 여드름 생성완화, 피부미백 및 주름개선 효과 등의 우수한 효과를 나타내는 화장료 조성물을 제공하는 것이다. 본 발명에 따른 화장료 조성물은 진세노사이드 Rh2 및 진세노사이드 Rg3를 단독으로 적용하였을 때보다 탁월한 피부 주름 개선 및 피부미백활성, 여드름 생성 완화와 아토피 피부염에 효과를 보인다.
또한, 본 발명의 화장제 조성물은 천연물질로서 식용 가능하므로 이를 유효성분으로 포함하는 본 발명의 조성물은 장기간 사용에도 안전한 이점이 있으며, 독성 및 부작용도 없다.-
公开(公告)号：KR101428682B1
公开(公告)日：2014-08-11
申请号：KR1020120085913
申请日：2012-08-06
Applicant: 강원대학교산학협력단 , 서원대학교산학협력단 , 주식회사 세바바이오텍
Abstract: 본 발명은 커피(원두 또는 부산물) 발효물 및 이의 추출물을 함유하는 기능성 커피 음료 조성물의 제조방법에 관한 것으로서, 보다 구체적으로는 가공되지 않은 커피 원두 자체 또는 대부분이 소비되지 않고 폐기되는 커피 부산물을 유산균을 이용하여 발효한 후 얻어진 발효액과 이의 발효액을 제외한 나머지 건체 커피 발효 잔여물을 에탄올 추출하여 얻어진 커피 발효 잔여 추출물을 유효성분으로 포함하는 기능성 커피 음료 조성물의 제조방법 및 이를 통해 제조된 기능성 커피 음료 조성물에 관한 것이다. 본 발명의 제조방법은 간단한 공정을 통해 커피 내의 클로로겐산의(Chlorogenic acid) 용출을 증진시킬 수 있으므로, 이러한 방법을 통해 제조된 본 발명의 조성물은 항산화 작용 및 항염 효과를 갖는 클로로겐산(Chlorogenic acid)을 다량 함유하고 있어 기능성 커피 음료 조성물로서 유용하게 사용될 수 있다. 또한 본 발명의 제조방법은 단가가 저렴한 원두 자체 또는 폐기되어 버려지는 커피 부산물을 활용하여 기능성을 갖는 새로운 건강 소재를 창출함으로써 폐기물의 재활용을 통한 친환경적인 효과도 기대할 수 있다.
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公开(公告)号：KR1020140043219A
公开(公告)日：2014-04-08
申请号：KR1020120107299
申请日：2012-09-26
Applicant: 강원대학교산학협력단 , 주식회사 두산에코비즈넷 , 서원대학교산학협력단
Abstract: The present invention relates to a method which prevents the low application stability of crops due to the excessive use of ethanol by enhancing the solubility of thiamine di-lauryl sulfate and is able to reduce the amount of thiamine di-lauryl sulfate used. A process of the present invention comprises: a dry nano-pulverizing step of pulverizing thiamine di-lauryl sulfate powders into a nano-size (1); a step of manufacturing a di-lauryl sulfate ethanol solution by spraying ethanol while spraying the manufacture thiamine di-lauryl sulfate nanoparticles through a nozzle (2); a di-lauryl sulfate solution manufacturing step of treating an ultrasonic process after adding distilled water in the thiamine di-lauryl sulfate ethanol solution (3); a step of consecutively irradiating visible rays through a pulse type laser while stirring the thiamine di-lauryl sulfate solution in order to have stability without the precipitation of the thiamine di-lauryl sulfate solution (4); and a step off adding tween80 which is a dispersant with functions forming a stable emulsion after the process (5). [Reference numerals] (AA) Manufacturing an aqueous solution capable of enhancing the solubility of TDS; (BB) Dry nanopulverizing pretreatment process; (CC) Pulverizing TDS through ultrafine vibration air; (DD) Compression strength: 34-37 kg.cm^2; (EE) Moisture content: 2-6%; (FF) Ultrasonic spraying process; (GG) Performing an ultrasonic process on a TDS ethanol solution in which TDS nanoparticles and ethanol are dissolved through a spraying nozzle; (HH) Spraying process: 100-150 g of TDS nanoparticels + 1 L of 40-60% ethanol; (II) Ultrasonic process: 10 ml of TDS ethanol solution + 4990 ml of distilled water; (JJ) Continuous pulse laser process; (KK) Irradiating pulse type laser; (LL) Pulse laser: 300 Mj, wavelength: 300-500 nm, Pulse width: 10 ns (FWHM), pulse repetition ratio:10 Hz; (MM) Adding 0.1-0.5% of a dispersant tween80 based on the whole volume when pulse laser is irradiated
Abstract translation: 本发明涉及通过提高硫代二月桂基硫酸硫胺素的溶解度而能够防止由于过量使用乙醇导致的农作物的低施用稳定性的方法，并且能够减少所用的二月桂基硫酸硫胺素的量。 本发明的方法包括：将二十二烷基硫酸硫胺素粉末粉碎成纳米尺寸（1）的干燥纳米粉碎步骤; 通过喷雾乙醇制造二月桂基硫酸盐乙醇溶液的步骤，同时通过喷嘴（2）喷洒生产的硫代二月桂基硫酸钠纳米颗粒; 在十二烷基硫酸硫胺素乙醇溶液（3）中加入蒸馏水后处理超声波处理的二月桂基硫酸盐溶液制造步骤; 在搅拌硫二胺二月桂基硫酸盐溶液的同时，通过脉冲式激光连续照射可见光以稳定而不沉淀硫代二月桂基硫酸盐溶液（4）的步骤; 并在步骤（5）之后加入吐温80，其为具有形成稳定乳液的功能的分散剂。 （附图标记）（AA）制造能够提高TDS溶解度的水溶液; （BB）干燥纳米粉末预处理工艺; （CC）通过超细振动空气粉碎TDS; （DD）抗压强度：34-37kg.cm ^ 2; （EE）水分含量：2-6％; （FF）超声波喷涂工艺; （GG）在TDS乙醇溶液中进行超声波处理，其中TDS纳米颗粒和乙醇通过喷嘴溶解; （HH）喷雾方法：100-150克TDS纳米颗粒+ 1升40-60％乙醇; （二）超声波处理：10ml TDS乙醇溶液+ 4990ml蒸馏水; （JJ）连续脉冲激光工艺; （KK）辐射脉冲激光器; （LL）脉冲激光：300Mj，波长：300-500nm，脉冲宽度：10ns（FWHM），脉冲重复比：10Hz; （MM）当脉冲激光照射时，基于整体积加入0.1-0.5％的分散剂tween80
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10.发明公开
公开(公告)号：KR1020140019185A
公开(公告)日：2014-02-14
申请号：KR1020120085912
申请日：2012-08-06
Applicant: 강원대학교산학협력단 , 서원대학교산학협력단
Abstract: The present invention relates to a cosmetic composition comprising Acer okamotoanum Nakai sap treated at an ultrahigh pressure and a manufacturing method thereof and more particularly, to Acer okamotoanum Nakai extract having anti-inflammatory effects and anti-atopic effects, which is treated at a low temperature of 25°C and a ultrahigh pressure of 300 to 500 MPa for 15 to 35 minutes, a functional cosmetic composition comprising the extract as an active ingredient and a manufacturing method thereof. The Acer okamotoanum Nakai extract treated at a low temperature and an ultrahigh pressure according to the present invention has enhanced storability because the growth of microorganisms contained in the extract is inhibited owing to the conducted ultrahigh pressure process, and reduces the loss and inactivity of useful bio-active substances contained in Acer okamotoanum Nakai, which is induced by a high temperature, owing to the treatment at a low temperature. Also the cosmetic composition comprising the Acer okamotoanum Nakai sap, which is manufactured by the method according to the present invention, as an active ingredient is safe in a long-term usage owing to the used natural materials and has no toxicity and no side effect. And the present invention can be useful in manufacturing functional cosmetics owing to the excellent effects of inhibiting inflammation and alleviating and treating atopy. [Reference numerals] (AA) Acer okamotoanum Nakai sap; (BB) Ultrahigh-pressure Acer okamotoanum Nakai sap; (CC) Acer mono sap; (DD) Ultrahigh-pressure Acer mono sap
Abstract translation: 本发明涉及一种包含在超高压下处理的中华猕猴桃汁和其制造方法的化妆品组合物，更具体地说，涉及具有抗炎作用和抗特应性作用的宏碁提取物，其在低温下处理 25℃，超高压300〜500MPa，15〜35分钟的功能化妆品组合物，其特征在于，含有提取物作为有效成分的功能性化妆品及其制造方法。 根据本发明处理的在低温和超高压下处理的Acer okamotoanum Nakai提取物具有增强的保存性，因为由于进行的超高压工艺，包含在提取物中的微生物的生长被抑制，并且减少了有用生物的损失和不活动 由于在低温下处理，由高温引起的Acer okamotoanum Nakai中含有的活性物质。 另外，通过本发明的方法制造的含有Acer okamotoanum Nakai sap的化妆品组合物作为活性成分，由于使用的天然材料而在长期使用中是安全的，并且没有毒性并且没有副作用。 本发明由于抑制炎症和减轻和治疗特应症的优异效果，可用于制造功能性化妆品。 [参考数字]（AA）Acer okamotoanum Nakai sap; （BB）超高压宏碁中ai汁; （CC）宏碁单汁液; （DD）超高压宏碁单汁液
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