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公开(公告)号:KR1020120089906A
公开(公告)日:2012-08-16
申请号:KR1020100131320
申请日:2010-12-21
Applicant: 강화군
Abstract: PURPOSE: A composition containing a fraction of Brassica campestris spp. rappa alcohol extract is provided to ensure anti-obesity effect. CONSTITUTION: A composition for anti-obesity contains a fraction which is prepared by fractioning Brassica campestris spp. rappa alcohol extract with hexane and ethyl acetate mixture. The alcohol is low alcohol of 1-4 carbon atoms. The composition is a food composition or pharmaceutical composition. The food composition is manufactured in the form of a tablet, granule, powder, beverage, and gruel.
Abstract translation: 目的:一种含有一些芥菜油菜的组合物。 提供拉巴醇提取物以确保抗肥胖效果。 构成:用于抗肥胖的组合物含有通过将芥菜油菜分馏而制备的级分。 拉巴醇提取物与己烷和乙酸乙酯混合。 醇是1-4个碳原子的低级醇。 组合物是食品组合物或药物组合物。 食品组合物以片剂,颗粒剂,粉末,饮料和稀释剂的形式制造。
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公开(公告)号:KR100949011B1
公开(公告)日:2010-03-23
申请号:KR1020090080306
申请日:2009-08-28
Applicant: 강화군
IPC: A61K31/34 , A61K36/282 , A61P3/06 , A61P9/10
Abstract: 본 발명은 사자발쑥 추출물을 포함하는 약학 조성물에 관한 것으로, 특히 사자발쑥 추출물 중 3β,4β-에폭시-8α-이소부티릴옥시구아이아-1(10),11(13)-디엔-12,6α-올라이드를 유효성분으로 포함하여 심장순환계 질환의 예방 및 치료에 효과적인 약학 조성물에 관한 것이다.
3β,4β-에폭시-8α-이소부티릴옥시구아이아-1(10),11(13)-디엔-12,6α-올라이드, 사자발쑥, 동맥경화, 고지혈증Abstract translation: 本发明涉及药物组合物,特别是3β,4β-环氧-8α-异丁氧基sajabal艾蒿提取物AH-1岁儿童(10),其包括sajabal艾蒿提取物,11(13) - 二烯-12, 6α-内酯为有效成分,对心血管疾病的预防和治疗有效。
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公开(公告)号:KR1020090064692A
公开(公告)日:2009-06-22
申请号:KR1020070131982
申请日:2007-12-17
Applicant: 강화군
IPC: A61K31/352 , A61K36/282 , A61P35/00
Abstract: A pharmaceutical composition containing an Artemisia princeps extract is provided to prevent and treat cancer and cardiac circulation disease by the effects of strong cytotoxicity and antioxidation activity. A composition for preventing and treating cancer comprises a 3beta,4beta-epoxy-8a-isobutyryloxyguaia-1(10),11(13)-diene-12.6a-olide as an active ingredient. The 3beta,4beta-epoxy-8a-isobutyryloxyguaia-1(10),11(13)-diene-12.6a-olide is isolated from an Artemisia princeps. The 3beta,4beta-epoxy-8a-isobutyryloxyguaia-1(10),11(13)-diene-12.6a-olide is contained in a ratio of 0.01-94 weight%. The cancer is ovarian cancer or leukemia.
Abstract translation: 提供含有青蒿提取物的药物组合物,以通过强的细胞毒性和抗氧化活性的作用预防和治疗癌症和心脏循环疾病。 用于预防和治疗癌症的组合物包含作为活性成分的3β,4β-环氧-8a-异丁酰氧基瓜亚-1(10),11(13) - 二烯-12.6a-olide。 从艾蒿中分离出3β,4β-环氧-8a-异丁酰氧基瓜亚-1(10),11(13) - 二烯-12.6a-olide。 3β,4β-环氧-8a-异丁酰氧基瓜亚-1(10),11(13) - 二烯-12.6a-olide的含量为0.01-94重量%。 癌症是卵巢癌或白血病。
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公开(公告)号:KR100865513B1
公开(公告)日:2008-10-29
申请号:KR1020070025560
申请日:2007-03-15
Applicant: 강화군
IPC: A61K36/282 , A61P3/04
Abstract: A composition for preventing and treating obesity is provided to show an effect for improving a liver function and an anti-obesity effect and not to have a side effect when users take the composition for preventing and treating obesity because the composition for preventing and treating obesity is natural food material. A composition for preventing and treating obesity has the alcoholic extract of 1 - 3 carbon number of the Artemisia princeps as an active ingredient. The gang-hwa mugwort extract is manufactured by adding the ethanol in the gang-hwa mugwort powder 2~10 times, and extracts at the room temperature for 12 ~24 hours. The extract is filtered into a centrifuge or the filter paper, precipitates are removed, and a supernatant is collected. The gang-hwa mugwort extract is manufactured into the powder form by drying the concentrated supernatant after the collected supernatant is concentrated.
Abstract translation: 提供了用于预防和治疗肥胖症的组合物,以显示用于改善肝功能和抗肥胖效果的效果,并且当用户采取预防和治疗肥胖症的组合物时不具有副作用,因为用于预防和治疗肥胖症的组合物是 天然食材。 用于预防和治疗肥胖症的组合物具有作为活性成分的艾蒿的1-3个碳数的醇提取物。 通过将乙炔加入组合艾蒿粉2〜10次,制成江阴艾蒿提取物,室温萃取12〜24小时。 将提取物过滤到离心机或滤纸中,除去沉淀物,并收集上清液。 将收集的上清液浓缩后,将干燥浓缩的上清液制成粉状的粉末状提取物。
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公开(公告)号:KR100710818B1
公开(公告)日:2007-04-24
申请号:KR1020060029319
申请日:2006-03-31
Applicant: 강화군
Abstract: 본 발명은 순무 추출물을 포함하는 당뇨병의 예방 및 치료용 조성물에 관한 것이다. 보다 구체적으로, 본 발명은 순무 추출물을 유효성분으로 함유하는 당뇨병의 예방 또는 치료용 약학적 조성물 및 식품 조성물에 관한 것이다.
본 발명에 따른 순무 추출물은 당뇨병으로 인한 당대사 및 지질대사 이상을 정상화하고 당뇨로 인해 비정상적으로 증가된 항산화 효소의 활성을 정상화함으로써 당뇨병의 예방 및 치료에 유용하게 사용될 수 있다.
순무 추출물, 당뇨병, 당대사, 지질대사, 항산화 효소Abstract translation: 本发明涉及用于预防和治疗糖尿病的组合物,其包含芜菁提取物。 更具体地说,本发明涉及含有萝卜提取物作为活性成分的用于预防或治疗糖尿病的药物组合物和食物组合物。
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公开(公告)号:KR100933737B1
公开(公告)日:2009-12-24
申请号:KR1020070131982
申请日:2007-12-17
Applicant: 강화군
IPC: A61K31/352 , A61K36/282 , A61P35/00
Abstract: 본 발명은 사자발쑥 추출물을 포함하는 약학 조성물에 관한 것으로, 특히 사자발쑥 추출물 중 3β,4β-에폭시-8α-이소부티릴옥시구아이아-1(10),11(13)-디엔-12,6α-올라이드를 유효성분으로 포함하여 암 질환 뿐 아니라 심장순환계 질환의 예방 및 치료에 효과적인 약학 조성물에 관한 것이다.
3β,4β-에폭시-8α-이소부티릴옥시구아이아-1(10),11(13)-디엔-12,6α-올라이드, 사자발쑥, 난소암, 백혈병, 동맥경화, 고지혈증Abstract translation: 本发明提供一种含有艾蒿提取物的药物组合物,其通过强细胞毒性和抗氧化活性的作用来预防和治疗癌症和心脏循环疾病。 用于预防和治疗癌症的组合物包含作为活性成分的3β,4β-环氧-8α-异丁酰氧基瓜氨酸-1(10),11(13) - 二烯-12.6a-内酯。 从Artemisia princeps中分离出3beta,4beta-环氧-8a-异丁酰氧基guiaia-1(10),11(13) - 二烯-12.6a-内酯。 以0.01-94重量%的比例包含3β,4β-环氧-8α-异丁酰氧基瓜氨酸-1(10),11(13) - 二烯-12.6a-内酯。 癌症是卵巢癌或白血病。
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公开(公告)号:KR1020090064700A
公开(公告)日:2009-06-22
申请号:KR1020070131992
申请日:2007-12-17
Applicant: 강화군
IPC: A61K31/352 , A61K36/282 , A61P35/00
Abstract: A pharmaceutical composition containing an Artemisia princeps is provided to suppress the proliferation of cervical tumor cell, lung cancer cell, and brain tumor cell and prevent and treat cardiac circulation diseases. A pharmaceutical composition for preventing and treating cancer comprises 0.01-96 weight% of eupafolin as an active ingredient. The eupafolin is isolated from an Artemisia princeps. The cancer is ovarian cancer, lung cancer or brain tumor. A pharmaceutical composition for preventing and treating cardiac circulation diseases comprises the eupafolin as an active ingredient. The cardiac circulation diseases are arteriosclerosis, hyperlipidemia, cerebral artery or coronary artery.
Abstract translation: 提供含有青蒿的药物组合物,以抑制宫颈肿瘤细胞,肺癌细胞和脑肿瘤细胞的增殖,并预防和治疗心脏循环疾病。 用于预防和治疗癌症的药物组合物包含0.01-96重量%的作为活性成分的儿茶酚素。 紫花苜蓿从艾蒿中分离出来。 癌症是卵巢癌,肺癌或脑肿瘤。 用于预防和治疗心脏循环疾病的药物组合物包括作为活性成分的欧蓬芬。 心脏循环疾病是动脉硬化,高脂血症,脑动脉或冠状动脉。
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公开(公告)号:KR101023899B1
公开(公告)日:2011-03-22
申请号:KR1020100043797
申请日:2010-05-11
Applicant: 강화군
IPC: A61K36/282 , A61P3/04 , A61P3/10 , A61P3/00
Abstract: PURPOSE: A composition containing Artemisia princeps pampanini fraction extract is provided to treat or prevent obesity and hyperlipidemia. CONSTITUTION: A method for preparing fraction extract of Artemisia princeps pampanini for preventing or treating obesity, hyperlipidemia, or diabetes comprises: a step of preparing alcohol extract of Artemisia princeps pampanini; a step of adding water to the alcohol extract; a step of extracting the alcohol extract with a mixture solvent of n-hexane and ethyl acetate; and a step of extracting aqueous layer with a secondary mixture solvent of n-hexane and ethyl acetate to obtain a secondary fraction extract. The alcohol is an ethanol. A composition for preventing or treating obesity, hyperlipidemia, or diabetes contains the fraction extract of Artemisia princeps pampanini as an active ingredient. The composition is a pharmaceutical composition or food composition.
Abstract translation: 目的:提供含有青蒿素潘帕尼尼级分提取物的组合物,用于治疗或预防肥胖症和高脂血症。 构成:用于制备用于预防或治疗肥胖,高脂血症或糖尿病的艾蒿罂粟碱级分提取物的方法包括:制备蒿蒿的酒精提取物的步骤; 向酒精提取物中加入水的步骤; 用正己烷和乙酸乙酯的混合溶剂萃取醇提取物的步骤; 以及用正己烷和乙酸乙酯的二次混合溶剂萃取水层以获得二级馏分提取物的步骤。 酒精是乙醇。 用于预防或治疗肥胖症,高脂血症或糖尿病的组合物含有作为活性成分的白花蒿的级分提取物。 组合物是药物组合物或食物组合物。
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公开(公告)号:KR100933738B1
公开(公告)日:2009-12-24
申请号:KR1020070131988
申请日:2007-12-17
Applicant: 강화군
IPC: A61K31/352 , A61K36/282 , A61P35/00
Abstract: 본 발명은 사자발쑥 추출물을 포함하는 약학 조성물에 관한 것으로, 특히 사자발쑥으로부터 추출한 3-(2-메틸-부티릴옥시)-코스투-1(10),4(5)-디엔-12,6-올라이드(3-(2-methyl-butyryloxy)-costu-1(10),4(5)-dien-12,6-olide)를 유효성분으로 포함하여 암 질환 뿐 아니라 심장순환계 질환의 예방 및 치료에 효과적인 약학 조성물에 관한 것이다.
3-(2-메틸-부티릴옥시)-코스투-1(10),4(5)-디엔-12,6-올라이드, 사자발쑥, 난소암, 백혈병, 심장순환계 질환Abstract translation: 提供含有艾蒿的药物组合物以诱导卵巢癌和白血病细胞的凋亡并抑制胆固醇酰基转移酶的活化。 用于预防和治疗癌症的药物组合物包含作为活性成分的(3-(2-甲基丁酰氧基) - 缩水甘油-1(10),4(5) - 二烯-12,6-内酯)。 从蒿属植物中分离出(3-(2-甲基丁酰氧基) - 羰基-1(10),4(5) - 二烯-12,6-内酯),其含量为0.01-99重量%。 癌症是卵巢癌和白血病。 用于预防和治疗心脏循环疾病的药物组合物包含作为活性成分的(3-(2-甲基丁酰氧基) - 缩水甘油-1(10),4(5) - 二烯-12,6-内酯)。 心脏循环疾病是高脂血症,冠心病,动脉硬化或心肌梗塞。
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公开(公告)号:KR100929098B1
公开(公告)日:2009-11-30
申请号:KR1020090069668
申请日:2009-07-29
Applicant: 강화군
IPC: C07D307/77 , A61K31/352 , A61K36/282 , A61P35/00
Abstract: 본 발명은 사자발쑥 추출물에 관한 것으로, 특히 사자발쑥으로부터 추출한 3-(2-메틸-부티릴옥시)-코스투-1(10),4(5)-디엔-12,6-올라이드(3-(2-methyl-butyryloxy)-costu-1(10),4(5)-dien-12,6-olide)에 관한 것이다.
3-(2-메틸-부티릴옥시)-코스투-1(10),4(5)-디엔-12,6-올라이드, 사자발쑥, 난소암, 백혈병, 심장순환계 질환Abstract translation: 提供含有从提取物中分离的艾蒿提取物或倍半萜烯化合物的药物组合物具有强烈的细胞毒性,例如抑制癌细胞增殖或诱导细胞凋亡。 用于治疗癌症或心脏循环系统疾病的药物组合物包含从提取物中分离的化学式1的艾蒿提取物或倍半萜烯化合物。 化学式1的倍半萜烯化合物是3-(2-甲基丁酰氧基) - 羰基-1(10),4(5) - 二烯-12,6-内酯。 生产化学式1的倍半萜化合物的方法包括:将干燥的蒿属植物在C1-C4的低级醇中浸渍24小时的步骤; 以及过滤,压缩和分离的步骤。
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