Abstract:
PURPOSE: A manufacturing method of biodegradable microspheres is provided to control the size of microspheres by controlling flux of a microfluidic device, and to manufacture micro particles with a dimple structure on surface and a porous structure inside at the same time. CONSTITUTION: A manufacturing method of biodegradable microspheres comprises: a step of manufacturing a polymer solution comprising a biodegradable polymer with non-aqueous phase, and a polymer solution comprising phase change material(PCM); a step of manufacturing continuous phase by dissolving a hydrophilic surfactant into distilled water; a step of connecting a continuous and a non-continuous microfludic devices by tubes; a step of solidification of the polymer spheres through O/W(oil-in-water) emulsion method by using the microfludic devices.
Abstract:
본 발명은 의료용도로 적용되는 생분해성 고분자를 기반으로 마이크로플루딕 디바이스를 이용하여 내부 및 외부에 구조적 복잡성을 보유하고 균일한 크기를 갖는 미립자 및 그 제조방법에 관한 것이다. 보다 상세하게는 연속상, 비 연속상 마이크로플루딕 디바이스를 튜브로 연결하는 단계와, 상기 튜브 내로 연속상을 위한 물 흐름을 도입하여 균일한 크기의 미립자를 형성하는 단계, 상기 미립자를 고형화시키는 단계를 포함하는 미립자의 제조방법이다.
Abstract:
PURPOSE: A manufacturing method of a biodegradable microsphere is provided to obtain micro particles having structural complexity inside and outside at the same time through simple method on the basis of biodegradable polymers using for medical treatment. CONSTITUTION: A manufacturing method of a biodegradable microsphere comprises a step of manufacturing polymer solution containing biodegradable polymers and phase change material, and a step of solidifying the biodegradable microsphere by manufacturing emulsion oil-in-water through dispersing the polymer solution into continuous phase in which hydrophilic surfactant is dissolved. The biodegradable polymer is poly(D,L-lactic acid) or poly(lactic acid-co-glycolic acid). The biodegradable polymer is added to have the concentration to organic solvent in the polymer solution of 6-10 %(w/w).
Abstract:
The present invention relates to a composition for preventing and treating diabetes containing a Ribes diacantha Pallas extract which is capable of controlling high blood pressure by the inflow of sugar, rapidly recovers the blood sugar of a user to an original blood sugar state, improves diet efficiency and glycometabolism, and reduces the load on kidneys to be effectively used for preventing and treating diabetes.
Abstract:
The present invention relates to an anti-allergic and anti-inflamatory composition containing N-arachidonoyl serotonin (NA-5HT,N-arachidonoyl serotonin) as an active ingredient, having no toxicity while having excellent anti-allergic and anti-inflamatory effectiveness so as to be safely used. The composition of the present invention can be used as a pharmaceutical composition or a cosmetic composition, and can be used in manufacturing health functional food.
Abstract:
PURPOSE: A lysophosphatidylethanolamine derivative and an anti-inflammatory composition containing the same are provided to suppress peritonitis induced by zymosan A in vivo and to enhance anti-inflammatory cytokine(IL-10) generation. CONSTITUTION: A lysophosphatidylethanolamine derivative is denoted by chemical formulas 1-4. A pharmaceutical composition for preventing and treating inflammatory diseases contains the derivative or a pharmaceutically acceptable salt thereof as an active ingredient. The inflammatory diseases are asthma, periodontitis, stomatitis, peritonitis, gastritis, lymphocytic enteritis, arthritis, nephritis, hepatitis, or degenerative diseases. The composition is used as an oral formulation or an injection formulation. A health food for preventing and treating inflammatory diseases contains the derivative or salt thereof as an active ingredient.
Abstract:
PURPOSE: Candied radish slices having excellent anti-oxidation ability, and a producing method thereof are provided to use ginger, citron, and turmeric to improve the functionality of the candied radish slices. CONSTITUTION: A producing method of candied radish slices comprises the following steps: slicing fresh radish, and parboiling the radish slices before removing the moisture; mixing the radish slices with water, saccharide, ginger juice, citron, and turmeric, and boiling the mixture after adding lemon or organic acid, and agar; and drying the boiled radish slices. 100 parts of radish slices by weight are mixed with 20-40 parts of ginger juice by weight, 20-60 parts of citron by weight, and 0.04-0.16 parts of turmeric by weight. The saccharide is selected from the group consisting of honey, grain syrup, sugar, and oligosaccharide, and 25-75 parts of saccharide by weight is mixed with 100 parts of radish slices by weight.