公开(公告)号：KR1020010017748A

公开(公告)日：2001-03-05

申请号：KR1019990033413

申请日：1999-08-13

Applicant: 대한민국(농촌진흥청장)

Inventor： 김금숙 ,  박창기 ,  성재덕 ,  김현태 ,  한상익 ,  곽용호 ,  임무상

IPC: C07H15/20 ,  C07H1/08

Abstract: PURPOSE: Provided is a natural aspaoligonin isolated from Asaragus oligoclonos Maxim. Also, an isolating method thereof is provided. The aspaoligonin is potentially developed into medical supplies if its medicinal action is examined. CONSTITUTION: The aspaoligonin represented by formula (1) is isolated from Asaragus oligoclonos Maxim. by the following steps of: grinding the dried roots of Asaragus oligoclonos Maxim.; extracting the grinded roots with methanol at room temperature; filtering the extract solution and concentrating the filtrate under vacuum condition; dissolving the concentrates in distilled water and defatting the solution with ether; extracting the water layer of the defatted solution with butanol to obtain the butanol fragment; purifying the butanol fragment by chromatography on silica gel to obtain 20 fragments; and purifying the 5th fragment by using Sep-Pak C18 to obtain aspaoligonin.

Abstract translation: 目的：提供从Asaragus oligoclonos Maxim分离的天然天冬白。素。 此外，还提供了其隔离方法。 如果检查其药物作用，则天冬氨酸可能发展成为医疗用品。 构成：式（1）所代表的天冬白蛋白从蛔虫（Asaragus oligoclonos Maxim）中分离出来。 通过以下步骤：研磨Asaragus oligoclonos Maxim的干燥根; 在室温下用甲醇萃取研磨的根; 过滤提取液并在真空条件下浓缩滤液; 将浓缩物溶解在蒸馏水中并用乙醚脱溶液; 用丁醇提取脱脂溶液的水层，得到丁醇片; 通过硅胶色谱纯化丁醇片段得到20个片段; 并用Sep-Pak C18纯化第5片，得到天冬氨酸。

公开(公告)号：KR100341795B1

公开(公告)日：2002-06-26

申请号：KR1019990033413

申请日：1999-08-13

Applicant: 대한민국(농촌진흥청장)

Inventor： 김금숙 ,  박창기 ,  성재덕 ,  김현태 ,  한상익 ,  곽용호 ,  임무상

IPC: C07H15/20 ,  C07H1/08

Abstract: 본발명은방울비짜루(남옥대)로부터단리되어천연에서처음으로보고되는물질(Aspaoligonin)에관한것이다.