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公开(公告)号：KR100790888B1
公开(公告)日：2008-01-02
申请号：KR1020060093681
申请日：2006-09-26
Applicant: 삼성전자주식회사
IPC: A61M5/14
CPC classification number: B01L9/527 , B01L3/5021 , B01L3/5027 , B01L2200/027 , B01L2300/0832 , B01L2400/0409 , C12M23/16
Abstract: A centrifugal force-based fluid loading device with a simple structure is provided to load a fluidic sample to a microfluidic chip at a proper drive pressure using a centrifugal force. A centrifugal force-based fluid loading device includes: a fluid storage part(21) to store a fluidic sample to be loaded into a microfluidic chip(10); a loading part(20) having a chip receiving part to accommodate a part of the microfluidic chip, such as a portion including an injection port(14); and a support part(30) having a support formed in a manner to support the other part of the microfluidic chip. The chip receiving part has an exit(24) of the fluid storage part. The microfluidic chip has an outlet(15) on the opposite side of the injection port to make a fluid flow from the injection port to the outlet, and the support part has a discharged fluid storage(31) to keep the discharged fluid from the outlet.
Abstract translation: 提供具有简单结构的基于离心力的流体加载装置，以使用离心力将流体样品以合适的驱动压力加载到微流体芯片。 基于离心力的流体加载装置包括：流体存储部分（21），用于存储待加载到微流体芯片（10）中的流体样品; 具有用于容纳微流体芯片的一部分的芯片接收部分的装载部分（20），诸如包括注射端口（14）的部分; 以及具有以支撑微流体芯片的另一部分的方式形成的支撑件的支撑部分（30）。 芯片接收部分具有流体存储部分的出口（24）。 微流体芯片在注入口的相对侧上具有出口（15），以使得流体从注入口流到出口，并且支撑部分具有排出的流体储存器（31），以将排出的流体从出口 。
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公开(公告)号：KR100785010B1
公开(公告)日：2007-12-11
申请号：KR1020060031490
申请日：2006-04-06
Applicant: 삼성전자주식회사
CPC classification number: C12N15/1006 , C12N15/1003
Abstract: A method and a device for purifying a DNA are provided to use a solid support without any surface treatment and bind a nucleic acid without a special additive in a wide pH range, thereby being usefully used for a lab-on-a chip. A method for purifying a DNA comprises a step of binding the DNA to a solid support by contacting a DNA-containing sample and a sample containing a kosmotropic salt selected from the group consisting of SO4^2-, HPO4^2-. OH^-, F^-, HCOO^-, and CH3COO^- on the solid support of which the surface has a hydrophilic functional group. A device for purifying a DNA comprises a kosmotropic salt storage portion which is communicated to the solid support through a microchannel and supplies the kosmotropic salt and the solid support having a hydrophilic functional group on the surface thereof. The device further comprises a DNA elution buffer solution storage portion communicated to the solid support through the microchannel and supplying a DNA elution buffer solution to the solid support. A lab-on-a-chip comprises the DNA purifying device.
Abstract translation: 提供用于纯化DNA的方法和装置以使用固体支持物而不进行任何表面处理，并且在宽的pH范围内结合无特殊添加剂的核酸，从而有用地用于芯片实验室。 用于纯化DNA的方法包括通过使含DNA样品和含有选自SO 4 2-，HPO 4 -2-的选择性差异盐的样品接触来将DNA结合到固体支持物的步骤。 在其表面具有亲水官能团的固体载体上具有OH - ，F - - ，HCOO - - 和CH 3 COO - 。 用于纯化DNA的装置包括通过微通道与固体支持物连通并在其表面上提供具有亲水性官能团的去离子盐和固体支持物的感应盐储存部分。 该装置还包括通过微通道与固体支持物连通的DNA洗脱缓冲溶液储存部分，并将DNA洗脱缓冲溶液供应至固体支持物。 DNA实验室包括DNA纯化装置。
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