公开(公告)号：KR1020140024221A

公开(公告)日：2014-02-28

申请号：KR1020130096070

申请日：2013-08-13

Applicant: 서울대학교산학협력단

Inventor： 강헌중 ,  왕웨이홍 ,  김희영 ,  기리아왓두트가젠드라

IPC: C07D307/58 ,  A61K31/341 ,  A61P31/04 ,  A61P37/00

CPC classification number: C07D307/58

Abstract: The present invention relates to a butenolides compound, the stereoisomers and enantiomers thereof, precursors thereof which is hydrolyzable in the body, or a pharmaceutically acceptable salt, the antimicrobial activity, preventive activity against immune diseases, effects in preventing or treating cancer, and preventive activity against fouling of a medical introducer.

Abstract translation: 本发明涉及丁内酯化合物，其立体异构体和对映异构体，其在体内可水解的前体或其药学上可接受的盐，抗微生物活性，针对免疫疾病的预防活性，预防或治疗癌症的预防作用和预防活性 防止医疗导师的结垢。

公开(公告)号：KR101599426B1

公开(公告)日：2016-03-07

申请号：KR1020130096070

申请日：2013-08-13

Applicant: 서울대학교산학협력단

Inventor： 강헌중 ,  왕웨이홍 ,  김희영 ,  기리아왓두트가젠드라

IPC: C07D307/58 ,  A61K31/341 ,  A61P31/04 ,  A61P37/00

CPC classification number: C07D307/58

Abstract: 본발명은부테놀라이드계화합물, 그의입체이성질체, 그의거울상이성질체, 생체내에서가수분해가능한그의전구체또는약제학적으로허용가능한그의염 및그들이갖는항균활성, 면역질환치료및 예방활성, 암의예방또는치료효능및 의료용삽입기기의오손방지활성에관한것이다.