公开(公告)号：KR1020080011933A

公开(公告)日：2008-02-11

申请号：KR1020060072692

申请日：2006-08-01

Applicant: 아주대학교산학협력단

Inventor： 민철기 ,  김현창 ,  홍승표 ,  김한집 ,  최동순

IPC: A61K38/26

CPC classification number: A61K38/08 ,  A61L2/0082

Abstract: A novel compound is provided to show anti-bacterial activity. A composition comprising the same is provided to prevent or treat efficiently bacterial infection or disinfect a non-living object. A compound is represented by the formula(1) of peptide-L-PNA, where the peptide is an amino acid sequence, L is an linker or a bond, and PNA is a peptide nucleic acid and selected from the group consisting of -CGCCCAATAAT-NH2, -TCAGCGTCAGT-NH2, -CCAACATCTCA-NH2 and -TCTCAGTCCCA-NH2, wherein A is N-(2-aminoethyl)-N-(N6-(benzyloxycarbonyl)adenine-9-yl-acetyl)glycine, T is N-(2-aminoethyl)-N-(thymine-1-yl-acetyl)glycine, G is N-(2-aminoethyl)-N-(N2-(benzyloxycarbonyl)guanine-9-yl-acetyl)glycine and C is N-(2-aminoethyl)-N-(N4-(benzyloxycarbonyl)cytosine-1-yl-acetyl)glycine. A composition for preventing or treating bacterial infection comprises the compound and a pharmaceutically acceptable carrier. A method for disinfecting a non-living object comprises a step of contacting a composition for disinfecting the non-living object comprising the compound and a carrier with the non-living object.

Abstract translation: 提供了一种新的化合物来显示抗菌活性。 提供含有该组合物的组合物以有效地预防或治疗非活体物质的细菌感染或消毒。 化合物由肽-L-PNA的式（1）表示，其中肽是氨基酸序列，L是接头或键，PNA是肽核酸，并且选自-CGCCCAATAAT -NH2，-TCAGCGTCAGT-NH2，-CCAACATCTCA-NH2和-TCTCAGTCCCA-NH2，其中A是N-（2-氨基乙基）-N-（N6-（苄氧羰基）腺嘌呤-9-基 - 乙酰基）甘氨酸，T是N - （2-氨基乙基）-N-（胸腺嘧啶-1-基 - 乙酰基）甘氨酸，G是N-（2-氨基乙基）-N-（N 2 - （苄氧基羰基）鸟嘌呤-9-基 - 乙酰基）甘氨酸，C是 N-（2-氨基乙基）-N-（N4-（苄氧基羰基）胞嘧啶-1-基 - 乙酰基）甘氨酸。 用于预防或治疗细菌感染的组合物包含该化合物和药学上可接受的载体。 消毒非生物的方法包括将包含化合物和载体的非生物体与非活体物质接触的组合物接触的步骤。

公开(公告)号：KR1020070004407A

公开(公告)日：2007-01-09

申请号：KR1020060002853

申请日：2006-01-10

Applicant: 아주대학교산학협력단

Inventor： 김순동 ,  심윤주 ,  최동순 ,  김현숙 ,  조위덕

IPC: G06Q50/30

CPC classification number: G06Q50/30

Abstract: A method and a system for community computing are provided to design a model collaborating in a community unit by organically combining persons, computing devices, and services, as a community model is applied to a ubiquitous computing environment. A community purpose part contains a final purpose to be attained by the community. A community skin part supports privacy protection/information hiding in the computing environment probably opening excessive information by encapsulating the community. A community policy part supports an operation of the community by being diversely combined as a policy set for functions of the community. A community member part performs mutual collaboration to attain the final purpose by binding the community. A community action part provides context-based action to be taken by the community member part to attain the final purpose.

Abstract translation: 提供社区计算的方法和系统，通过有机地结合人，计算设备和服务来设计在社区单元中协作的模型，因为社区模型被应用于普遍存在的计算环境。 社区目的部分包含社区要实现的最终目的。 社区皮肤部分支持隐藏在计算环境中的隐私保护/信息，可能通过封装社区来打开过多的信息。 社区政策部分通过多元化地结合为社区功能的政策，来支持社区的运作。 社区成员部分通过约束社区实现相互协作，达到最终目的。 社区行动部分提供社区成员部分采取的基于上下文的行动，以达到最终目的。

公开(公告)号：KR100884693B1

公开(公告)日：2009-02-18

申请号：KR1020060002853

申请日：2006-01-10

Applicant: 아주대학교산학협력단

Inventor： 김순동 ,  심윤주 ,  최동순 ,  김현숙 ,  조위덕

IPC: G06Q50/30

Abstract: 본 발명은 커뮤니티의 목적, 정책, 멤버, 멤버 상호간의 작동, 커뮤니티 작동 상황, 커뮤니티 휴면 상황 등이 정의되어 하나의 커뮤니티를 형성하는 커뮤니티 형성 단계; 상기 커뮤니티 형성 단계 이후 커뮤니티가 실제 커뮤니티 멤버를 구성하고 동작해야 할 시점을 기다리는 커뮤니티 대기 단계; 상기 커뮤니티 대기 단계 이후 커뮤니티가 상황 정보를 감시하다가 커뮤니티 작동 상황이 되면 스스로 활성화되어 동작을 시작하는 커뮤니티 동작 단계; 상기 커뮤니티 동작 단계 이후 커뮤니티가 커뮤니티의 목적을 만족시키거나 휴면할 상황이 되면 커뮤니티가 스스로 동작을 일시적으로 멈추고 다음 커뮤니티 동작 단계를 대기하는 커뮤니티 휴면 단계; 및 커뮤니티가 더 이상 동작할 필요가 없는 경우에 스스로 모든 동작을 종료하는 커뮤니티 종료 단계를 포함하는 커뮤니티 컴퓨팅 방법 및 시스템에 관한 것이다.
유비쿼터스, 유비쿼터스 컴퓨팅, 커뮤니티, 커뮤니티 컴퓨팅

公开(公告)号：KR1020060098780A

公开(公告)日：2006-09-19

申请号：KR1020050018715

申请日：2005-03-07

Applicant: 아주대학교산학협력단

Inventor： 조위덕 ,  이정태 ,  강경란 ,  최동순

IPC: G06F9/06

CPC classification number: G06F9/546 ,  G06F9/541 ,  G06F9/544 ,  H04L67/2823

Abstract: A system for supporting the diversity of a ubiquitous computing environment according to the present invention has a message bus including a message broker managing an intermediary role of delivering an actual message between the subsystems and a messaging adaptor managing an interface function between the message broker and the subsystems, wherein the messaging adaptor is installed in the subsystems and includes a first adaptor including a first application port for interfacing with the subsystems, and a second adaptor including a second application port for interfacing with the first adaptor and the broker port operating with the message broker.

公开(公告)号：KR100814718B1

公开(公告)日：2008-03-19

申请号：KR1020060072692

申请日：2006-08-01

Applicant: 아주대학교산학협력단

Inventor： 민철기 ,  김현창 ,  홍승표 ,  김한집 ,  최동순

IPC: A61K38/26

Abstract: 본 발명은 하기 식1로 표시되는 화합물로서, 펩티드-L-PNA (식1), 식1 중 펩티드는 아미노산 서열이고, L은 링커 또는 결합이고, PNA는 펩티드 핵산으로서, -CGCCCAATAAT-NH
2 , -TCAGCGTCAGT-NH
2 , -CCAACATCTCA-NH
2 및 -TCTCAGTCCCA-NH
2 로 이루어지는 PNA 모이어티 군으로부터 선택되고, 여기서 A는 N- (2-아미노에틸)-N- (N6- (벤질옥시카르보닐)아데닌-9-일-아세틸)글리신이고, T는 N- (2-아미노에틸)-N- (티민-1-일-아세틸)글리신이고, G는 N- (2-아미노에틸)-N- (N2- (벤질옥시카르보닐)구아닌-9-일-아세틸)글리신이고, C는 N- (2-아미노에틸)-N- (N4- (벤질옥시카르보닐)시토신-1-일-아세틸)글리신인 PNA인, 화합물., 그를 포함하는 박테리아 감염 예방 또는 치료용 조성물, 비생물체를 소독하기 위한 조성물 및 비생물체를 소독하는 방법을 제공한다.
PNA, 16S 리보좀 RNA 유전자, 항 박테리아제

公开(公告)号：KR100694804B1

公开(公告)日：2007-03-14

申请号：KR1020050041766

申请日：2005-05-18

Applicant: 아주대학교산학협력단

Inventor： 민철기 ,  최동순

IPC: A61K48/00

CPC classification number: C12N15/1138 ,  A61K48/00 ,  C12N2310/14 ,  C12N2310/53

Abstract: 본 발명은 인간 신데칸-1 유전자 발현의 RNA 간섭을 유도하는 핵산 분자 및 약제학적으로 허용가능한 담체를 포함하는 자궁 내막암 치료 또는 예방용 조성물 및 그를 인간에 투여하는 단계를 포함하는 자궁 내막암 치료 또는 예방 방법을 제공한다.
신데칸-1, RNA 간섭, shRNAi

公开(公告)号：KR100679865B1

公开(公告)日：2007-02-07

申请号：KR1020050018715

申请日：2005-03-07

Applicant: 아주대학교산학협력단

Inventor： 조위덕 ,  이정태 ,  강경란 ,  최동순

IPC: G06F9/06

CPC classification number: G06F9/546 ,  G06F9/541 ,  G06F9/544 ,  H04L67/2823

Abstract: A system for supporting the diversity of a ubiquitous computing environment according to the present invention has a message bus including a message broker managing an intermediary role of delivering an actual message between the subsystems and a messaging adaptor managing an interface function between the message broker and the subsystems, wherein the messaging adaptor is installed in the subsystems and includes a first adaptor including a first application port for interfacing with the subsystems, and a second adaptor including a second application port for interfacing with the first adaptor and the broker port operating with the message broker.

公开(公告)号：KR1020060119155A

公开(公告)日：2006-11-24

申请号：KR1020050041766

申请日：2005-05-18

Applicant: 아주대학교산학협력단

Inventor： 민철기 ,  최동순

IPC: A61K48/00

CPC classification number: C12N15/1138 ,  A61K48/00 ,  C12N2310/14 ,  C12N2310/53

Abstract: A composition for treating or preventing endometrial cancer is provided to inhibit growth of tumor by inhibiting the expression of syndecan-1 in endometrial cancer cell through shRNAi. The prophylactic or preventive composition for endometrial cancer comprises a nucleic acid molecule inducing RNA interference of human syndecan-1 gene expression and a pharmaceutically acceptable carrier. In the composition, the nucleic acid molecule has a sequence described as SEQ ID : NO. 1 or 2 and the human syndecan-1 gene has an NCBI access number of NM_002977.

Abstract translation: 提供一种用于治疗或预防子宫内膜癌的组合物，通过shRNAi抑制子宫内膜癌细胞中syndecan-1的表达来抑制肿瘤生长。 用于子宫内膜癌的预防或预防组合物包括诱导人类syndecan-1基因表达的RNA干扰的核酸分子和药学上可接受的载体。 在组合物中，核酸分子具有SEQ ID NO： 1或2，人类syndecan-1基因的NCBI接入号为NM_002977。