公开(公告)号：KR101249389B1

公开(公告)日：2013-04-03

申请号：KR1020100105854

申请日：2010-10-28

Applicant: 재단법인대구경북과학기술원

Inventor： 정상원 ,  김은주 ,  김현철 ,  이세근 ,  이성준 ,  김민관

IPC: C08J3/075 ,  C08G65/00 ,  C08G79/02 ,  A61K9/06

Abstract: 본원은 음이온을 가지는 고분자와 양이온을 포함하는 수화젤을 개발하여 젤 지속성이 향상되고 자극반응성을 가지는 수화젤을 제공하고자 한다.

公开(公告)号：KR1020120048724A

公开(公告)日：2012-05-16

申请号：KR1020100105854

申请日：2010-10-28

Applicant: 재단법인대구경북과학기술원

Inventor： 정상원 ,  김은주 ,  김현철 ,  이세근 ,  이성준 ,  김민관

IPC: C08J3/075 ,  C08G65/00 ,  C08G79/02 ,  A61K9/06

Abstract: PURPOSE: A hydrogel is provided to give stimulation reaction by including negative polymers and positive ions and to maintain gel persistence. CONSTITUTION: A hydrogel comprises a hydrophilic or amphipathic polymer including two or more of phosphate(PO4 ^2) groups and polyhydric cation corresponding with negative charged phosphate (PO4^2). The polyhydric cation is selected from low molecular weight compound or polycation including more than 2 cations selected from -NH3 and -N2(CH3)3, and positive charged metal ion having more than bivalent, and combinations thereof. The hydrogel additionally includes 0-20 parts by weight of additive selected from NaCl, CaCl2, NaCSN, PEG and a combination thereof based on 100.0 parts by weight of membranous polymers.

Abstract translation: 目的：提供水凝胶，通过包括负性聚合物和阳离子进行刺激反应并保持凝胶持久性。 构成：水凝胶包含亲水或两亲性聚合物，其包括磷酸盐（PO4）2基团和对应于负电荷磷酸盐（PO 4 -2）的多羟基阳离子）的两种或多种。 多羟基阳离子选自低分子化合物或聚阳离子，包括多于2个选自-NH 3和-N 2（CH 3）3的阳离子，以及具有多于二价的带正电荷的金属离子及其组合。 基于100.0重量份膜聚合物，水凝胶另外包含0-20重量份的选自NaCl，CaCl 2，NaCSN，PEG及其组合的添加剂。