Abstract:
A method for determining monoisotopic masses by determining isotopic clusters is provided to ensure a high accuracy and high processing speed in determining the position of a real monoisotopic peak even when a polypeptide mixture has a composition away from a general amino acid composition, and complex peaks of isotopic clusters appear in the mass spectrum. A method for determining possibility models of isotopic clusters for determining monoisotopic masses of isotopic clusters comprises the steps of: approximating each peak intensity (Ik), ratio of two peak intensities(Ik+1/Ik) and multiplication of two ratios(Ik-1Ik_1/I^2) obtained from three peaks in the isotopic clusters to a possibility formula; and calculating the highest, lowest and average functions(Rmax(k, M), Rmin(k, M), Ravg(k, M)) of the k^th ratio of a polypeptide with a mass of M, and the highest, lowest and average functions (RPmin(k, M), RPmax(k, M), RPavg(k, M)) of the multiplication of the k^th ratio of the polypeptide with a mass of M by using the possibility formula.
Abstract:
상관관계 합의 선형시간 계산 방법을 개시한다. 상관관계 합의 선형시간 계산 방법은 두 신호의 상관관계(cross correlation)의 합을 계산하는 상관관계 합의 계산 방법에 있어서, 실험 대상이 되는 상대신호(target signal)를 제1 입력신호로 입력받고 기준신호(base signal)를 제2 입력신호로 입력받는 단계; 및, 상기 제1 입력신호와 제2 입력신호 중 어느 한 입력신호의 각 원소를 더하는 덧셈 연산을 먼저 수행한 후 상기 덧셈 연산의 결과를 다른 입력신호의 각 원소에 곱하는 곱셈 연산을 수행하는 연산 순서에 따라 상관관계의 합을 계산하는 단계를 포함할 수 있다. 프로테오믹스(proteomics), 단백질 동정, 탠덤 질량 분석(tandem mass spectrometry), 시퀘스트(SEQUEST), FFT(Fast Fourier Transform), 상관관계(cross-correlation) 연산, 유사도, 선형 시간
Abstract:
PURPOSE: A method for calculating linear time of cross-correlation is provided to drastically shorten data processing time for correlation sum. CONSTITUTION: An experiment spectrum is obtained(S210). A fixed number of candidate amino acid ranks is selected among selected peptide amino acid ranks in a peptide rank database(S220). A virtual spectrum is generated through the selected candidate amino acid rank(S230). Similarity between the experiment spectrum and the virtual spectrum is calculated through a linear time operation method of a cross-correlation sum. The peptide amino acid rank of the experiment spectrum is determined(S240).
Abstract:
PURPOSE: An antibacterial polymer composition is provided to ensure strong sterilizing power or antibacterial activity by reducing copper contained in a polymer. CONSTITUTION: An antibacterial polymer composition includes a copper-containing polymer and organic solvent. The antibacterial polymer composition has antibacterial activity for microorganism through reduction processing. The copper-containing polymer has a repeating unit represented by formula 1. A method for forming an antibacterial polymer film comprises the steps of: forming a copper-containing polymer film on a substance by applying the polymer composition; and imparting an antibacterial property for microorganism to the copper-containing polymer film by reducing the copper-containing polymer film using a reducing agent through chemical reduction, thermal reduction, and photo reduction.