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公开(公告)号：KR100525786B1
公开(公告)日：2005-11-03
申请号：KR1020040017738
申请日：2004-03-16
Applicant: 재단법인서울대학교산학협력재단 , 알앤엘생명과학주식회사
IPC: A61K36/484 , A61P35/00
Abstract: 본 발명은 에스트로젠 활성 및 암 세포에 대한 증식 억제 활성을 나타내는 감초(
Glycyrrhiza uralensis Fisch) 추출물 또는 이솔리퀴리틴(isoliquiritin)을 유효성분으로 하는 파이토에스트로젠(phytoestrogen) 조성물에 관한 것으로, 본 발명의 감초 추출물 또는 이솔리퀴리틴은 에스트로젠성은 나타내나 안드로젠성은 나타내지 않고, 내분비계 장애물질인 비스페놀-A의 활성을 억제하며, 유방암 세포를 비롯한 암 세포의 증식을 저해하므로, 파이토에스트로젠으로서 호르몬 대체 치료 및 유방암의 예방 및 치료를 위해 사용될 수 있다.-
2.发明公开
公开(公告)号：KR1020040082951A
公开(公告)日：2004-09-30
申请号：KR1020040017738
申请日：2004-03-16
Applicant: 재단법인서울대학교산학협력재단 , 알앤엘생명과학주식회사
IPC: A61K36/484 , A61P35/00
CPC classification number: A61K36/484 , A23V2200/308 , A61K2236/33
Abstract: PURPOSE: A phytoestrogenic composition containing a Glycyrrhizae Radix extract or isoliquiritin having potent phytoestrogenic activity is provided. The composition exhibits phytoestrogenic properties, inhibits the activity of bisphenol A as an endocrine disrupting substance and suppresses proliferation of cancer cells including breast cancer cells and is thus used for hormone replacement therapy and prevention and treatment of breast cancer. CONSTITUTION: The phytoestrogenic composition contains a Glycyrrhizae Radix extract or isoliquiritin as an effective ingredient and is used for prevention and treatment of osteoporosis, cardiac and circulatory disorders, menopause symptoms or cancer. The Glycyrrhizae Radix extract is prepared by extracting in an organic solvent selected from the group consisting of C1-4 alcohol, C1-4 aqueous alcohol solution, ethyl acetate, trichloromethyl and hexane. The C1-4 alcohol is methanol or ethanol. A food composition for treatment of the symptoms of menopause and prevention of cancer contains 0.1 to 50% by weight of the organic solvent extract of Glycyrrhizae Radix extract, based on the total weight of the food composition.
Abstract translation: 目的：提供含有甘草提取物或具有强烈植物雌激素活性的异喹啉的植物雌激素组合物。 该组合物具有植物雌激素特性，抑制双酚A作为内分泌干扰物质的活性，抑制包括乳腺癌细胞在内的癌细胞的增殖，因此用于激素替代治疗和预防和治疗乳腺癌。 构成：植物雌激素组合物含有甘草提取物或异喹啉作为有效成分，用于预防和治疗骨质疏松症，心脏和循环系统疾病，绝经症状或癌症。 甘草提取物通过在选自C 1-4醇，C 1-4醇水溶液，乙酸乙酯，三氯甲基和己烷的有机溶剂中萃取来制备。 C 1-4醇是甲醇或乙醇。 基于食物组合物的总重量，用于治疗更年期症状和预防癌症的食物组合物含有甘草提取物的有机溶剂提取物的0.1-50重量％。
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3.发明授权인진쑥, 오가피 및 마늘의 추출물들을 포함하는 동물의성장 촉진용 조성물 및 이를 포함하는 사료 조성물 有权Injinssuk，刺五加和饲料组合物以及用于生长促进组合物在动物中，包括大蒜的提取物
公开(公告)号：KR100528313B1
公开(公告)日：2005-11-15
申请号：KR1020050037825
申请日：2005-05-06
Applicant: 알앤엘생명과학주식회사
IPC: A23K1/14
Abstract: 본 발명은 인진쑥, 오가피 및 마늘의 추출물들을 포함하는 동물의 성장 촉진용 조성물 및 이를 포함하는 사료 조성물에 관한 것으로, 본 발명에 따른 동물의 성장 촉진용 조성물은 우수한 성장 호르몬 분비 촉진 효과를 나타내어 동물의 성장을 촉진시키며, 특히 이를 포함하는 동물용의 사료 조성물로서 가축에게 투여될 때 우수한 증체, 육질 개선 및 산유량 증가 등의 효과를 나타낸다.
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公开(公告)号：KR1020030002213A
公开(公告)日：2003-01-08
申请号：KR1020010038966
申请日：2001-06-30
Applicant: 알앤엘생명과학주식회사
IPC: A61K36/284 , A61K36/076 , A61K36/258 , A61P35/04
Abstract: PURPOSE: A composition containing medicinal plants such as Atractylodis Rhizoma Alba, Hoelen, Ginseng Radix, Glycyrrhizae Radix or the like is provided which has an excellent cancer and cancer metastasis suppressing effect while having angiogenesis inhibiting activity. CONSTITUTION: The composition comprises 4 to 14% by weight of Atractylodis Rhizoma Alba, 4 to 14% by weight of Hoelen, 4 to 14% by weight of Ginseng Radix, 2 to 12% by weight of Glycyrrhizae Radix, 2 to 12% by weight of Dioscoreae Rhizoma, 2 to 12% by weight of Dolichoris Semen, 2 to 12% by weight of Nelumbinis Semem, 2 to 12% by weight of Coicis Semen, 2 to 12% by weight of Amomi Semen, 2 to 12% by weight of Platycodi Radix, 2 to 12% by weight of Oldenlandiae diffusae Herba, 4 to 14% by weight of Herba houttuyniae and 4 to 14% by weight of Agrimoniae Herba.
Abstract translation: 目的：提供含有药用植物如Atractylodis Rhizoma Alba，Hoelen，人参，甘草等的组合物，其具有优异的癌症和癌症转移抑制作用，同时具有血管生成抑制活性。 组成：组合物包含4至14重量％的白术，4至14重量％的Hoelen，4至14重量％的人参，2至12重量％的甘草，2至12重量％的甘草 Dioscoreae Rhizoma的重量，Diichreis Semen的2至12重量％，Nelumbinis Semem的2至12重量％，Coicis Semen的2至12重量％，Amomi Semen的2至12重量％，Amomi Semen的2至12重量％ 桔梗的重量，2至12重量％的野草兰草，4至14重量％的草药和4至14重量％的草地草。
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公开(公告)号：KR1020020084875A
公开(公告)日：2002-11-13
申请号：KR1020010024275
申请日：2001-05-04
Applicant: 알앤엘생명과학주식회사 , 강경선
Abstract: PURPOSE: A composition for hormone replacement therapy containing a natural extract such as persimmon leaves extract which produces an estrogen-like material is provided which can be used as a health food product or a therapeutic agent for hormone replacement therapy of a menopausal woman. CONSTITUTION: Persimmon leaves are extracted 1 to 20 times with water, extracted at 60 to 100deg.C for 1 to 6hr, filtered or centrifuged and then concentrated under reduced pressure, or they are extracted 5 to 20 times with lower alcohol, preferably 60 to 80% ethanol at 60 to 100deg.C while flowing backward for 1 to 6hr, filtered and then concentrated. For example, 100g persimmon leaves are added to 2L ethanol, flowed backward while heating at 90deg.C for 3hr, filtered and then concentrated under reduced pressure. Thereafter, the extract is applied to Saccharomyces cerevisiae to identify estrogenicity.
Abstract translation: 目的：提供一种用于激素替代疗法的组合物，其含有天然提取物如柿子叶提取物，其产生雌激素样物质，其可用作绝经妇女的保健食品或激素替代疗法的治疗剂。 构成：将柿叶用水提取1〜20次，在60〜100℃下提取1〜6小时，过滤或离心，减压浓缩，或用低级醇提取5〜20次，优选60〜 80％乙醇，60至100℃，同时向后流动1至6小时，过滤并浓缩。 例如，将100g柿子叶加入到2L乙醇中，在90℃加热3小时后向后流动，过滤，然后减压浓缩。 此后，将提取物施用于酿酒酵母以鉴定雌激素。
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Patent Agency Ranking
公开(公告)号：KR1020020084874A
公开(公告)日：2002-11-13
申请号：KR1020010024274
申请日：2001-05-04
Applicant: 알앤엘생명과학주식회사 , 강경선
Abstract: PURPOSE: A composition containing an extract of Castanea crenata Sieb. et Zucc. producing a human estrogen receptor-binding material as an effective component is provided. Because the composition has androgenicity, it can be used as a prophylactic and therapeutic agent for androgen deficiency and prostate cancer as well as a health food composition. CONSTITUTION: The pharmaceutical composition contains 0.1 to 50% by weight of a Castanea crenata extract, in which the extract is administered at daily doses of 0.001 to 100mg/kg through an oral, transdermal, subcutaneous, intravenous or muscular pathway. For example, 100g Castanea crenata Sieb. et Zucc. is added to 2L ethanol, flowed backward while heating at 90deg.C for 3hr, filtered and then concentrated under reduced pressure.
Abstract translation: 目的：一种含有Castanea crenata Sieb提取物的组合物。 等Zucc。 提供了作为有效成分的人雌激素受体结合材料。 因为该组合物具有雄激素性，所以可以用作雄激素缺乏和前列腺癌的预防和治疗剂以及保健食品组合物。 构成：药物组合物含有0.1至50重量％的卡氏炭疽提取物，其中通过口服，透皮，皮下，静脉内或肌肉途径以0.001至100mg / kg的日剂量施用提取物。 例如，100g Castanea crenata Sieb。 等Zucc。 加入到2L乙醇中，在90℃加热3小时，向后流动，过滤，然后减压浓缩。
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公开(公告)号：KR1020060046978A
公开(公告)日：2006-05-18
申请号：KR1020040092536
申请日：2004-11-12
Applicant: 알앤엘생명과학주식회사
IPC: A23L1/30
CPC classification number: A23L33/105 , A23L31/00
Abstract: 본 발명은 차가버섯 추출물을 유효성분으로 함유하는 바이러스 질환의 예방 및 개선을 위한 조성물에 관한 것으로서, 더욱 상세하게는, 사람 면역결핍 바이러스(HIV), 헤르페스 심플렉스 바이러스(HSV), PMWS 바이러스, PRRS 바이러스, PED 바이러스, TGE 바이러스, 파보 바이러스 및 디스템퍼 바이러스에 대해 우수한 항바이러스 활성을 갖는 차가버섯 추출물을 포함하는 조성물에 관한 것이다.
본 발명의 차가버섯 추출물은 천연물 유래의 물질로써 독성 및 부작용을 나타내지 않으면서도, 다양한 바이러스에 대해 탁월한 항바이러스 활성을 나타내므로, 이를 포함하는 조성물은 바이러스 질환의 예방 및 개선에 효과적이고 안전한 식품 또는 사료용 조성물로 유용하게 이용될 수 있다.
차가버섯, 항바이러스, HIV, HSV-
公开(公告)号：KR1020040076351A
公开(公告)日：2004-09-01
申请号：KR1020030011670
申请日：2003-02-25
Applicant: 알앤엘생명과학주식회사
IPC: C12N1/20
Abstract: PURPOSE: A lactic acid bacterium and a method for prevention and treatment of fowl typhoid using the same microorganism are provided. The microorganism has improved antimicrobial activity to bacteria causing fowl typhoid. CONSTITUTION: The lactic acid bacterium Lactobacillus para casei KLB58(KCTC 10373BP) has antimicrobial activity to bacteria causing fowl typhoid such as Salmonella gallinarum and Salmonella enteritidis, wherein Lactobacillus para casei KLB58 (KCTC 10373BP) is isolated from Koreans. The method for prevention and treatment of fowl typhoid comprises adding Lactobacillus para casei KLB58 (KCTC 10373BP), the cultured medium thereof, or an extract of Lactobacillus para casei KLB58 (KCTC 10373BP) into the fodder or drink water for fowls, and feeding the fodder or drink water to fowls.
Abstract translation: 目的：提供乳酸菌和使用相同微生物预防和治疗家禽伤寒的方法。 微生物对引起禽类伤寒的细菌具有改善的抗菌活性。 构成：乳酸菌Lactobacillus para casei KLB58（KCTC 10373BP）对致病禽类的细菌具有抗菌活性，如沙门氏沙门氏菌和肠炎沙门氏菌，其中从韩国人中分离出乳酸杆菌KLB58（KCTC 10373BP）。 预防和处理家禽伤寒的方法包括将乳杆菌属乳杆菌KLB58（KCTC10373BP），其培养基或将乳杆菌乳杆菌KLB58（KCTC 10373BP）的提取物加入饲料或饮用水中，并将饲料 或者喝水给家禽。
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公开(公告)号：KR1020030061102A
公开(公告)日：2003-07-18
申请号：KR1020020001474
申请日：2002-01-10
Applicant: 알앤엘생명과학주식회사
IPC: A61K31/70 , A61K38/43 , A61K36/484 , A61P29/00
CPC classification number: A61K31/722 , A61K31/315 , A61K33/30 , A61K38/4873 , A61K2300/00
Abstract: PURPOSE: A composition having excellent killing effect and antiinflammatory effect on mastitis-causing bacteria while effectively lowering somatic cell count in the milk of dairy cattle is provided. Therefore, the composition can be effectively used in increasing the quality of the milk while being useful for the prevention and treatment of mastitis. CONSTITUTION: A composition for lowering a somatic cell count in the milk of dairy cattle and prevention or treatment of mastitis thereof comprises 0.1 to 20% by weight of a mixture of chitosan-chitooligosaccharide in a ratio of 1:0.5 to 1:0.75, 0.1 to 10% by weight of bromelain, 0.01 to 10% by weight of Glycyrrhizae Radix as an active ingredient and additionally 0.5 to 30% by weight of zinc or a salt thereof and 10 to 60% by weight of fermented material. The fermented material is a culture of a microorganism selected from the group consisting of Aspergillus oryzae, Aspergillus niger, Aspergillus terreus, Saccharomyces cerevisiae and Bacillus subtilis.
Abstract translation: 目的：提供对乳腺炎细菌有效降低体细胞计数的具有优异杀灭效果和抗炎作用的组合物。 因此，该组合物可有效地用于增加乳的质量，同时可用于预防和治疗乳腺炎。 构成：用于降低乳牛乳中体细胞计数和预防或治疗乳腺炎的组合物包含0.1至20重量％的壳聚糖 - 壳寡糖混合物，其比例为1:0.5至1:0.75,0.1 至10重量％的菠萝蛋白酶，0.01至10重量％的甘草作为活性成分，另外0.5至30重量％的锌或其盐和10至60重量％的发酵材料。 发酵材料是选自米曲霉（Aspergillus oryzae），黑曲霉（Aspergillus niger），土曲霉（Aspergillus terreus），酿酒酵母（Saccharomyces cerevisiae）和枯草芽孢杆菌（Bacillus subtilis）的微生物的培养物。
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公开(公告)号：KR1020030037989A
公开(公告)日：2003-05-16
申请号：KR1020010069381
申请日：2001-11-08
Applicant: 알앤엘생명과학주식회사
IPC: A01N43/68
Abstract: PURPOSE: Provided is an insecticide composition containing, as an ingredient, cyromazine and deltamethrin which removes the larva and imago of insect pests, thereby effectively killing mosquitos and flies. CONSTITUTION: The insecticide composition contains 0.1 to 20% by weight of cyromazine of the formula(1), 0.1 to 20% by weight of deltamethrin of the formula(2), 0.1 to 99% by weight of a carrier and 0.1 to 10% by weight of a surfactant. The mixing ratio of cyromazine and deltamethrin is 1:1 to 1:10. The composition is directly sprayed on a livable habitat for insect pests in an amount of 10 to 50mg/m¬2 or added to animal feeds or animal excrement.
Abstract translation: 目的：提供一种除虫马和溴氰菊酯作为成分的杀虫剂组合物，可去除害虫的幼虫和成虫，从而有效杀死蚊子和苍蝇。 构成：杀虫剂组合物含有0.1〜20重量％的式（1）的环丙嗪，0.1〜20重量％的式（2）的溴氰菊酯，0.1〜99重量％的载体和0.1〜10重量％ 的表面活性剂。 环丙嗪和溴氰菊酯的混合比为1:1至1:10。 将组合物直接喷洒在10〜50mg / m 2的昆虫害虫栖息地上，或者添加到动物饲料或动物粪便中。
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