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    用于制造生物传感器元件以检测葡萄糖的方法,生物传感器元件和用于检测葡萄糖的方法

    公开(公告)号:KR1020130060963A

    公开(公告)日:2013-06-10

    申请号:KR1020110127297

    申请日:2011-11-30

    Abstract: PURPOSE: A method for manufacturing a biosensor element for detecting glucose and the biosensor element and a method for detecting glucose using the same are provided to fix a hydrophilic molecular film on a metalloid polymer nancomposite, to generate a compound by inducing covalent bond of graphene oxide, and to improve blood glucose detection. CONSTITUTION: A method for manufacturing a biosensor element comprises: a step of fixing a hydrophilic molecular film onto a nanocomposite(S110); a step of inducing covalent bond of the nanocomposite and graphene and generating a compound(S120); and a step of modifying glucose oxidase(S130). The nanocomposite is PEG-SIO2@Ag. The hydrophilic molecular film is 3-APTES(3-aminopropyltriethoxysilane). The fixation is performed by fixing 3-APTES on PEG-SIO2@Ag. [Reference numerals] (AA) Start; (BB) End; (S110) Fix a hydrophilic molecular film onto a metalloid polymer nanocomposite(MPNC); (S120) Generate a compound by inducing the covalent bond of graphene oxide(GO) and the metalloid polymer nanocomposite on which the hydrophilic molecular film is fixed; (S130) Modify glucose oxidase(GOX) on the compound

    Abstract translation: 目的:提供一种用于制造用于检测葡萄糖的生物传感元件和生物传感器元件的方法和使用其的检测葡萄糖的方法,以将亲水性分子膜固定在准金属聚合物纳米复合物上,通过诱导氧化石墨烯的共价键来产生化合物 ,并改善血糖检测。 构成:生物传感元件的制造方法,包括:将亲水性分子膜固定在纳米复合体上的工序(S110); 诱导纳米复合材料和石墨烯的共价键并产生化合物的步骤(S120); 和修饰葡萄糖氧化酶的步骤(S130)。 纳米复合材料是PEG-SIO2 @ Ag。 亲水性分子膜是3-APTES(3-氨基丙基三乙氧基硅烷)。 通过将3-APTES固定在PEG-SIO2 @ Ag上进行固定。 (附图标记)(AA)开始; (BB)结束; (S110)将亲水性分子膜固定在准金属聚合物纳米复合材料(MPNC)上; (S120)通过诱导氧化石墨烯(GO)和固定有亲水性分子膜的准金属聚合物纳米复合物的共价键生成化合物; (S130)修饰化合物上的葡萄糖氧化酶(GOX)

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