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1.发明授权15-히드록시프로스타글란딘 디히드로게나제 및 ＰＧＥ2 활성을 조절하는 황칠나무 추출물의 용도 有权用于控制15-羟基丙氨酸脱氢酶和PGE2活性的DENDROPANAX MORBIFERA提取物的使用
公开(公告)号：KR101244964B1
公开(公告)日：2013-03-18
申请号：KR1020120057252
申请日：2012-05-30
Applicant: 조선대학교산학협력단
CPC classification number: A61K36/25 , A23L33/105 , A23V2002/00 , A23V2200/30 , A23V2200/3202 , A23V2250/21
Abstract: PURPOSE: A pharmaceutical composition containing a Dendropanax morbifera Lev. extract is provided to prevent and treat burn, wound, aphthous ulcer, and gastritis. CONSTITUTION: A pharmaceutical composition for preventing and treating burn, wound, aphthous ulcer, peptic ulcer, or gastritis containing a Dendropanax morbifera Lev. extract as an active ingredient. The extract is prepared using water including purified water, methanol, ethanol, butanol, hexane, chloroform, dichloromethane, ethyl acetate, or a mixture thereof.
Abstract translation: 目的：含有Dendropanax morbifera Lev的药物组合物。 提取物用于预防和治疗烧伤，伤口，口疮性溃疡和胃炎。 构成：用于预防和治疗含有Dendropanax morbifera Lev的烧伤，伤口，口疮性溃疡，消化性溃疡或胃炎的药物组合物。 提取物作为活性成分。 该提取物是用纯净水，甲醇，乙醇，丁醇，己烷，氯仿，二氯甲烷，乙酸乙酯或其混合物的水制备的。
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公开(公告)号：KR101487059B1
公开(公告)日：2015-01-27
申请号：KR1020120068155
申请日：2012-06-25
Applicant: 조선대학교산학협력단
Abstract: 본 발명은 황칠나무 추출물을 유효성분으로 포함하는 발모 촉진용 조성물에 관한 것으로, 보다 상세하게는 황칠나무 추출물을 유효성분으로 포함하는 발모 촉진용 화장료 조성물, 탈모 방지, 발모 촉진 및 두피 개선용 약제학적 조성물 및 기능성 식품에 관한 것이다. 본 발명에 따른 황칠나무 추출물은 15-PGDH 활성을 억제하여 PGE
2 을 증가시키는 활성이 우수하며, 또한 남성형 탈모의 중요기전인 AR 시그럴닝을 억제하는 기전을 통해 남성형 탈모에도 우수한 효과가 있음을 규명하였다. 따라서 본 발명은 탈모를 방지하고 발모를 촉진시키는 효과가 우수함을 확인함으로써 발모 촉진용 화장품, 의약품 및 기능성 식품의 제조에 유용하게 사용할 수 있는 효과가 있다.-
公开(公告)号：KR1020140000813A
公开(公告)日：2014-01-06
申请号：KR1020120068155
申请日：2012-06-25
Applicant: 조선대학교산학협력단
Abstract: The present invention relates to a composition for promoting hair growth which includes extract of dendropanax morbifera as an active ingredient and, more specifically, to a cosmetic composition for promoting hair growth which includes dendropanax morbifera as an active ingredient, and to a pharmaceutical composition and a health supplement for preventing hair loss, promoting hair growth, and improving scalp health which includes the dendropanax morbifera as the active ingredient. The dendropanax morbifera according to the present invention suppresses activities of 15-PGDH to increase PGE2 and has excellent effects on male alopecia through a mechanism which suppresses AR signaling which is an important mechanism for male alopecia. Therefore the present invention can be useful for manufacturing cosmetics, medicines, and functional foods for promoting hair growth by confirming effects on promoting hair growth and preventing hair loss. [Reference numerals] (AA) Vehicle CTL 0.5% minoxidil DMHE(ED50 � 10); (BB) Female; (CC) Male
Abstract translation: 本发明涉及一种促进头发生长的组合物，其包括树枝状植物提取物作为活性成分，更具体地，涉及用于促进毛发生长的化妆品组合物，其包括作为活性成分的树突状细胞，以及药物组合物和 用于防止脱发的健康补充剂，促进毛发生长，以及改善头皮健康，其包括树突状细菌作为活性成分。 根据本发明的树突状血红蛋白抑制15-PGDH增加PGE2的活性，并通过抑制作为男性脱发的重要机制的AR信号的机制对男性脱发具有优异的效果。 因此，通过确认促进毛发生长和防止脱发的效果，本发明可用于制造用于促进头发生长的化妆品，药物和功能性食品。 （标号）（AA）载体CTL 0.5％米诺地尔DMHE（ED50 10）; （BB）女; （CC）男
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