Abstract:
본 발명은 겔화제 및 이온차폐제를 이용하여 L-아스코르빌산을 안정화시키는 방법, 상기의 안정화된 L-아스코빌산을 함유하는 수-유-수 다중 에멀젼을 제조하는 방법 및 이를 함유하는 화장료 조성물에 관한 것이다. 상기 안정화된 L-아스코빌산을 함유하는 수-유-수 다중 에멀젼의 제조방법은 내수상에 겔화제 및 이온차폐제를 첨가하고, 수산화나트륨으로 pH를 중성으로 조절하여 안정화된 L-아스코빌산을 함유하는 수-유 에멀젼을 제조하는 단계; 및 상기 수-유 에멀젼을 친수성 계면활성제로 재 유화하여 안정한 수-유-수 다중 에멀젼을 수득하는 단계를 포함한다.
Abstract:
본 발명은 유효성분으로 진주 단백질 나노캡슐을 함유하는 피부 각질세포 분화촉진 또는 피부 보습용 피부외용제 조성물에 관한 것이다. 또한, 상기 조성물은 심해효소(Thermus thermophilus ferment)를 더 함유하여 우수한 노화방지 효과를 나타낸다.
Abstract:
본 발명은 4~20㎛의 파장영역에서 강한 파동에너지를 방출하는 결정성 무기광물을 피부에 효과적으로 도입함으로써, 혈행을 촉진시켜 피부 세포를 활성화시킬 수 있고, 아울러 피부 보습 및 피부 노화 방지 효과를 제공할 수 있는 피부 외용제 조성물에 관한 것이다.
Abstract:
PURPOSE: Kojic acid derivatives and a preparation process thereof are provided, thereby inhibiting the melanin formation, so that the whiteness of the skin can be improved. CONSTITUTION: Kojic acid derivatives represented by formula(1) are provided, wherein R is C6H4-1,4-, C6H4-1,3-, CH=CHCH=CH, C5H3N-2,5- or C5H3N-3,5-. A process for preparing the Kojic acid derivatives of formula(1) comprises the steps of: (a) reacting thionyl chloride as chlorides with kojic acid in an organic solvent to prepare kojyl chloride; (b) reacting terephthalic acid, pyridine dicarboxylic acid and 2,4-hexadiene dioic acid with hydroxide salt in an organic solvent to prepare terephthalic acid salt, pyridine dicarboxylic acid salt and 2,4-hexadiene dioic acid salt; and (c) reacting terephthalic acid salt, pyridine dicarboxylic acid salt and 2,4-hexadiene dioic acid salt with kojyl chloride to prepare kojic acid dimer, wherein the chloride of the step (a) is thionyl chloride, oxalyl chloride, phosphorous trichloride and phosphorous oxychloride; the organic solvent of the step (a) is chloroform, methylene chloride, tetrahydrofuran, acetone, toluene and benzene; the hydroxide salt of the step (b) is sodium hydroxide and potassium hydroxide; and the organic solvent of the step (b) is ethanol, methanol, butanol and isopropyl alcohol.
Abstract translation:目的:提供曲酸衍生物及其制备方法,由此抑制黑色素形成,从而可以改善皮肤的白度。 构成:提供由式(1)表示的曲酸衍生物,其中R为C 6 H 4-1,4-,C 6 H 4 1-3,CH = CHCH = CH,C 5 H 3 N-2,5-或C 5 H 3 N-3,5- 。 制备式(1)曲酸衍生物的方法包括以下步骤:(a)使亚硫酰氯如氯化物与曲酸在有机溶剂中反应制备曲酸氯化物; (b)使对苯二甲酸,吡啶二羧酸和2,4-己二烯二酸与氢氧化物盐在有机溶剂中反应以制备对苯二甲酸盐,吡啶二羧酸盐和2,4-己二烯二酸盐; (c)将对苯二甲酸盐,吡啶二羧酸盐和2,4-己二烯二酸盐与高氯酸盐反应制备曲酸二聚体,其中步骤(a)的氯化物是亚硫酰氯,草酰氯,三氯化磷和 三氯氧磷; 步骤(a)的有机溶剂为氯仿,二氯甲烷,四氢呋喃,丙酮,甲苯和苯; 步骤(b)的氢氧化物盐是氢氧化钠和氢氧化钾; 并且步骤(b)的有机溶剂是乙醇,甲醇,丁醇和异丙醇。
Abstract:
PURPOSE: Provided is a cosmetic composition containing, as natural material, an extract of Trichosanthes kirilowii and Origanum majorana which are harmless to a human body such as toxicity, skin irritation, allergy, skin trouble or the like. The cosmetic composition enhances skin elasticity and skin moisturization. CONSTITUTION: The cosmetic composition contains 0.1% by weight of a natural extract of Trichosanthes kirilowii and/or Origanum majorana, based on the total dried weight of the composition. Trichosanthes kirilowii and/or Origanum majorana are mixed with 5 to 15 times of a solvent, extracted at 50 to 95deg.C for 3 to 20hr. The extract is filtered, aged, then distilled. The solvent is at least one selected from the group consisting of purified water, purified water of ultra pure water, hydrous butylene glycol, hydrous ethanol, hydrous propylene glycol and hydrous glycerine.
Abstract:
PURPOSE: A method of producing W/O/W-type multiple emulsions containing L-ascorbic acid stabilized in an aqueous phase using a gelling agent and an ion-masking agent is provided. The W/O/W-type multiple emulsions exhibit excellent stability in an aqueous state and thus can be effectively applied to cosmetics and pharmaceutical industry for improving skin wrinkles, whitening the skin and preventing skin aging. CONSTITUTION: In a method for stabilizing L-ascorbic acid in an aqueous phase, a gelling agent and an ion-masking agent are added to the aqueous phase, the pH is adjusted to neutrality with sodium hydroxide to give a W/O emulsion containing stabilized L-ascorbic acid. The W/O emulsion is reemulsified with a hydrophilic surfactant to give W/O/W-type multiple emulsions. The ion-masking agent is one or more selected from the group consisting of a monovalent salt containing NaCl and Na3PO4, a divalent salt containing CaCl2, CuCl2 and MgSO4, all of multivalent salt derivatives having a salt structure and a mixture thereof.
Abstract translation:目的:提供使用胶凝剂和离子掩蔽剂制备在水相中稳定的含有L-抗坏血酸的W / O / W型多重乳液的方法。 W / O / W型多重乳液在水性状态下表现出优异的稳定性,因此可以有效地应用于化妆品和制药工业,以改善皮肤皱纹,增白皮肤和防止皮肤老化。 构成:在水相中稳定L-抗坏血酸的方法中,向水相中加入胶凝剂和离子掩蔽剂,用氢氧化钠将pH调节至中性,得到含稳定化的W / O乳液 L-抗坏血酸。 将W / O乳液用亲水性表面活性剂再乳化,得到W / O / W型多重乳液。 离子掩蔽剂是选自含有NaCl和Na 3 PO 4的一价盐,含有CaCl 2,CuCl 2和MgSO 4的二价盐,所有具有盐结构的多价盐衍生物及其混合物中的一种或多种。
Abstract:
There are provided a water-in stable kojic acid derivative represented by the following formula 1, a method for preparing the same and a skin-whitening cosmetic composition containing the same as an active ingredient:
Abstract:
PURPOSE: Provided is a cosmetic composition containing, as natural material, an extract of Trichosanthes kirilowii and Origanum majorana which are harmless to a human body such as toxicity, skin irritation, allergy, skin trouble or the like. The cosmetic composition enhances skin elasticity and skin moisturization. CONSTITUTION: The cosmetic composition contains 0.1% by weight of a natural extract of Trichosanthes kirilowii and/or Origanum majorana, based on the total dried weight of the composition. Trichosanthes kirilowii and/or Origanum majorana are mixed with 5 to 15 times of a solvent, extracted at 50 to 95deg.C for 3 to 20hr. The extract is filtered, aged, then distilled. The solvent is at least one selected from the group consisting of purified water, purified water of ultra pure water, hydrous butylene glycol, hydrous ethanol, hydrous propylene glycol and hydrous glycerine.
Abstract:
PURPOSE: Provided is a stabilized silver colloidal composition with good stabilization against agglomeration, oxidation and discoloration, and high antibacterial property by treating Ag colloidal solution with nitrogen-contained polymer and metal chelate. CONSTITUTION: The stabilized silver colloidal composition comprises the components of: 0.0001-5wt.% of Ag colloidal solution; 0.01-10wt.% of at least one water soluble polymer containing nitrogen selected from chitin, gelatin, collagen, polyacryl amide, etc.; 0.001-50wt.% of at least one metal chelate selected from ethylene diamine tetraacetic acid(EDTA), citric acid, beta-alamine diacetic acid, etc.; and the rest of water. The stabilized Ag colloidal composition is prepared by dropping Ag colloidal solution obtained by dispersing Ag particles(
Abstract:
PURPOSE: A skin preparation for external use containing crystalline inorganic mineral emitting strong wave energy at a wavelength area of 4 to 20 microns is provided which exhibits an excellent skin cell activating effect, skin moisturizing effect and skin aging-preventing effect. CONSTITUTION: The composition for external use for skin contains 0.01 to 25.0% by weight of crystalline inorganic mineral selected from tourmaline, crystal, precious stone, sapphire, ruby and turquoise, based on the total weight of the composition.