公开(公告)号：KR100750727B1

公开(公告)日：2007-08-22

申请号：KR1020060036394

申请日：2006-04-21

Applicant: 한국과학기술연구원

Inventor： 정혜선 ,  권익찬 ,  김성원 ,  이지숙 ,  김보경 ,  육순홍

IPC: A61K31/722 ,  A61K38/04

Abstract: A composition containing chitosan and N-acetyl-L-cysteine is provided to promote cholesterol-reducing effects of chitosan and reactive oxygen-removing effects of N-acetyl-L-cysteine by increasing enteric disintegration and bioavailability of chitosan and N-acetyl-L-cysteine. The composition contains 5-97 wt.% of chitosan having 50-90% deacetylation and molecular weight of 1,000-5,000,000 dalton and 3-95 wt.% of N-acetyl-L-cysteine having 82-88% deacetylation and molecular weight of 2,500-530,000 dalton, wherein the N-acetyl-L-cysteine is contained together with acetate or ascorbic acid. The food contains the composition containing chitosan and N-acetyl-L-cysteine.

Abstract translation: 提供含有壳聚糖和N-乙酰-L-半胱氨酸的组合物以通过增加壳聚糖和N-乙酰-L的肠溶性和生物利用度来促进壳聚糖的胆固醇降低作用和N-乙酰-L-半胱氨酸的活性氧去除作用 半胱氨酸。 该组合物含有5-97重量％脱乙酰度为50-90％，分子量为1,000-5,000,000道尔顿的壳聚糖和3-95重量％N-乙酰-L-半胱氨酸，其脱乙酰度为82-88％，分子量为 2,500-53万道尔顿，其中N-乙酰-L-半胱氨酸与乙酸盐或抗坏血酸一起被包含。 食物含有含有壳聚糖和N-乙酰-L-半胱氨酸的组合物。