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公开(公告)号:KR100258158B1
公开(公告)日:2000-06-01
申请号:KR1019980012351
申请日:1998-04-08
Applicant: 한국과학기술연구원
IPC: C07F7/02
Abstract: PURPOSE: Provided are a novel silylalkyl benzoic acid derivative which is a precursor of silylalkyl benzoamide working as effective bactericide. And its manufacturing method is also provided. CONSTITUTION: The novel silylalkyl benzoic acid derivative is represented by the formula (3), wherein R is hydrogen, or a methyl group; n is 1 or 2; and X is hydrogen, meta or para-fluoro, chloro, or methyl group. And its manufacturing method is characterized by the following steps of: i) reacting a silylalkylated benzene derivative of the formula (1) with methyl grignard at 0-50 deg.C in the presence of aluminum chloride as catalyst under nitrogen gas to manufacture a trimethylsilylalkyl benzene derivative of the formula (2); and ii) oxidizing the benzene derivative at 100-150 deg.C in the presence of acetic acid cobalt as catalyst.
Abstract translation: 目的:提供作为有效杀菌剂的甲硅烷基烷基苯甲酰胺的前体的新型甲硅烷基烷基苯甲酸衍生物。 并提供其制造方法。 构成:新型甲硅烷基烷基苯甲酸衍生物由式(3)表示,其中R是氢或甲基; n为1或2; 和X是氢,间位或对氟,氯或甲基。 其制造方法的特征在于以下步骤:i)在氮化铝存在下,在0-50℃下使式(1)的甲硅烷基烷基化的苯衍生物与甲基格氏体反应,制备三甲基甲硅烷基 式(2)的苯衍生物; 和ii)在乙酸钴作为催化剂存在下,在100-150℃氧化苯衍生物。
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公开(公告)号:KR100139089B1
公开(公告)日:1998-05-01
申请号:KR1019940033314
申请日:1994-12-08
CPC classification number: B01J31/38 , B01J31/0204 , B01J31/0274 , B01J31/0275 , B01J31/143 , C08F10/00 , C08F4/6465
Abstract: 본 발명은 Ziegler-Natta 형태의 중합촉매와 전자주게인 일반식(Ⅰ)로 표시되는 살란화합물로 이루어지는 올레핀 중합반응용 촉매계에 관한 것이다.
일반식(Ⅰ)에서 R
1 은 트리메틸실릴메틸 혹은 2-페닐프로필기를 나타내고, R
2 는 1-헥실, 시클로헥실, 시클로펜틸, 노말-부틸, 이소-부틸 또는 프로필 등의 C
3 -C
5 의 직쇄형, 고리형 혹은 가지달린 직쇄형의 알킬기를 나타내며, R
3 는 C
1 -C
3 의 알킬기이다.-
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公开(公告)号:KR100250958B1
公开(公告)日:2000-04-15
申请号:KR1019980011273
申请日:1998-03-31
Applicant: 한국과학기술연구원
IPC: C07F7/10
Abstract: PURPOSE: Provided are a silylalkylbenzoamid derivative of the formula (1) and its manufacturing method. And fungicide is also provided which containing the derivative as an active ingredient. CONSTITUTION: The silylalkylbenzoamid of the formula (1) is manufactured by treating silylalkylbenzoic acid derivative of the formula (2) with thiochloride to obtain benzoylchloride derivative; then reacting primary or secondary amine of the formula (3). Wherein R1 is hydrogen or linear or branched alkyl of C1-C4; R2 is branched or linear alkyl of C1-C4, cycloalkyl of C1-C6, aryl, phenyl, ortho-, meta-, or para-chlorophenyl; R3 is hydrogen or methyl group; X is hydrogen, meta- or para-fluoro, chloro or methyl group; Me is methyl group; and n is 1 or 2.
Abstract translation: 目的:提供式(1)的甲硅烷基烷基苯并酰胺衍生物及其制备方法。 并且还提供含有衍生物作为活性成分的杀真菌剂。 构成:式(1)的甲硅烷基烷基苯甲酰胺通过用氯化盐处理式(2)的甲硅烷基烷基苯甲酸衍生物制得苯甲酰氯衍生物; 然后使式(3)的伯胺或仲胺反应。 其中R1是氢或C1-C4的直链或支链烷基; R2是C1-C4的支链或直链烷基,C1-C6的环烷基,芳基,苯基,邻 - ,间 - 或对 - 氯苯基; R3是氢或甲基; X是氢,间 - 或对 - 氟,氯或甲基; 我是甲基; n为1或2。
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公开(公告)号:KR1019960022584A
公开(公告)日:1996-07-18
申请号:KR1019940033314
申请日:1994-12-08
Abstract: 본 발명은 Ziegler-Natta 형태의 중합촉매와 전자주게인 일반식(I)로 표시되는 실란화합물로 이루어지는 올레핀 중합반응용 촉매계에 관한 것이다.
일반식(I)에서 R′은 트리메틸실릴메틸 혹은 2-페닐프로필기를 나타내고, R
2 는 1-헥실, 시클로헥실, 시클로펜틸, 노말-부틸, 이소-부틸 또는 프로필 등의 C
3 -C
6 의 직쇄형, 고리형 혹은 가지달린 직쇄형의 알킬기를 나타내며, R
3 는 C
1 -C
3 인 알킬기이다.-
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公开(公告)号:KR101178793B1
公开(公告)日:2012-08-31
申请号:KR1020110027886
申请日:2011-03-29
CPC classification number: A61F2/82 , A61F2240/001 , A61F2250/0067 , A61F2310/00011 , A61F2310/00976 , A61L31/022 , A61L31/10 , A61L31/16
Abstract: PURPOSE: A method for coating heparin on the surface of a stent is provided to maintain a blood clot coagulation effect by improving heparin attachment stability. CONSTITUTION: A method for coating heparin on the surface of a stent is as follows. A coating solution is prepared by adding EDC(1-Ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride) and NHS(N-hydroxysulfosuccinimide) to a mixture solution of heparin and dopamine. A metal stent is dipped in the coating solution. The metal stent is made of a material selected from a group consisting of stainless steel, Co-Cr alloy, tantalum, and gold.
Abstract translation: 目的:提供一种在支架表面涂覆肝素的方法,以通过改善肝素附着稳定性来维持凝血凝血作用。 构成:在支架表面涂覆肝素的方法如下。 通过将EDC(1-乙基-3-(3-二甲基氨基丙基)碳二亚胺盐酸盐)和NHS(N-羟基磺基琥珀酰亚胺)加入到肝素和多巴胺的混合溶液中来制备涂布溶液。 将金属支架浸入涂布溶液中。 金属支架由选自不锈钢,Co-Cr合金,钽和金的材料制成。
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公开(公告)号:KR100142146B1
公开(公告)日:1998-07-01
申请号:KR1019940015933
申请日:1994-07-04
Applicant: 한국과학기술연구원
IPC: C07F7/18
Abstract: 본 발명은 일반식(Ⅰ)으로 표시되는, 유기 실란 4급 암모늄염 및 그의 제조방법을 제공한다.
상기식에서 R
1 은 (RO)
3 Si 또는 (MeO)
3 SiCH
2 [(MeO)
3 Si]CH이고, R
2 는 H 또는 (RO)
3 Si이며, Me는 메틸기이고 R은 탄소수 1-4개인 알킬기를 나타낸다.
본 발명의 유기 실란은 섬유류의 위생 처리제로서 유용하다.
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