약물 방출 조절용 다중 코팅 스텐트 및 그의 제조 방법
    4.
    发明公开
    약물 방출 조절용 다중 코팅 스텐트 및 그의 제조 방법 有权
    药物释放控制多层涂层手段及其制备方法

    公开(公告)号:KR1020120082086A

    公开(公告)日:2012-07-23

    申请号:KR1020110003369

    申请日:2011-01-13

    Abstract: PURPOSE: A multiple coating stent for controlling the medicine emission, and a manufacturing method thereof are provided to form three coating layers of different drugs by emitting ultrasonic waves. CONSTITUTION: A manufacturing method of a multiple coating stent for controlling the medicine emission comprises the following steps: ultrasonic wave-spraying a mixed solution of a first drug and a biodegradable polymer on the surface of a stent for forming a first coating layer; ultrasonic wave-spraying a biodegradable polymer solution on the upper side of the first coating layer for forming a second coating layer; ultrasonic wave-spraying a second mixed solution of a second drug and the biodegradable polymer on the upper side of the second coating layer for forming a third coating layer; and forming a fourth coating layer on the third coating layer using a biodegradable polymer. The first or second drug is selected from polyvinyl alcohol, saponin, carboxymethyl cellulose, or mono grylceride.

    Abstract translation: 目的:提供一种用于控制药物发射的多层涂层支架及其制造方法,通过发射超声波形成不同药物的三个涂层。 构成:用于控制药物发射的多层涂层支架的制造方法,包括以下步骤:在用于形成第一涂层的支架的表面上超声波喷射第一药物和生物降解性聚合物的混合溶液; 在第一涂层的上侧超声波喷射可生物降解的聚合物溶液,以形成第二涂层; 将第二药物和生物降解性聚合物的第二混合溶液超声波喷涂在第二涂层的上侧,以形成第三涂层; 以及使用可生物降解的聚合物在所述第三涂层上形成第四涂层。 第一种或第二种药物选自聚乙烯醇,皂角苷,羧甲基纤维素或单烯酸甘油酯。

    염기성 입자 및 세포외기질 물질을 포함하는 조직재생용 다공성 생분해성 고분자 지지체 및 이의 제조방법
    7.
    发明公开
    염기성 입자 및 세포외기질 물질을 포함하는 조직재생용 다공성 생분해성 고분자 지지체 및 이의 제조방법 审中-实审
    含有纳米陶瓷颗粒的生物可降解多孔聚合物和用于组织再生的细胞基质材料及其制备方法

    公开(公告)号:KR1020170025560A

    公开(公告)日:2017-03-08

    申请号:KR1020150122142

    申请日:2015-08-28

    Abstract: 본발명은유기용매상에서고분산성및 고안정성을갖는나노세라믹입자의제조와탈세포화된생체활성세포외기질물질의제조및 이를함유하는생분해성고분자를포함하는다공성생분해고분자생체이식물의염증억제및 조직재생향상용으로서의용도및 제조방법으로 (a) 세라믹입자표면을통상의지방산으로개질하여통상의유기용매상에서고안정성나노세라믹입자를얻는단계, (b) 상기세라믹입자표면을고분자로개질하여고분산성및 고안정성개질나노세라믹입자를얻는단계, (c) 탈세포화된동물조직또는세포유래생체활성세포외기질물질를얻는단계및 (d) 상기 (a), (b), (c)에서수득한나노세라믹입자와세포외기질물질을생분해성고분자와혼합하여기공유도체인얼음입자를이용한동결건조법을통해유무기복합고분자재료의다공성생분해성생체이식물제조방법에관한것이다.

    올메사탄 메독소밀의 정제방법
    8.
    发明公开
    올메사탄 메독소밀의 정제방법 有权
    OLMESARTAN MEDOXOMIL的纯化方法

    公开(公告)号:KR1020140029594A

    公开(公告)日:2014-03-11

    申请号:KR1020120094447

    申请日:2012-08-28

    Abstract: The present invention relates to a purification method of olmesartan medoxomil which comprises the following simple steps: dissolving the olmesartan medoxomil in a mixed solvent of halogenated alkane, and low class alcohol or low class ketone; and removing the halogenated alkane before crystalizing. The halogenated alkane is one or more compound selected from chloroform, methylene chloride, chlorodifluoromethane, dichlorofluoromethane, 1,1,2,2-tetrachloroethane, 1,1,1,2-tetrachloroethane, and ethylene chloride.

    Abstract translation: 本发明涉及奥美沙坦酯的纯化方法,其包括以下简单步骤:将奥美沙坦酯在卤代烷烃和低级醇或低级酮的混合溶剂中溶解; 并在结晶之前除去卤代烷烃。 卤代烷烃是一种或多种选自氯仿,二氯甲烷,氯二氟甲烷,二氯氟甲烷,1,1,2,2-四氯乙烷,1,1,1,2-四氯乙烷和二氯乙烷的化合物。

Patent Agency Ranking