公开(公告)号：KR101897606B1

公开(公告)日：2018-09-12

申请号：KR1020160182994

申请日：2016-12-29

Applicant: 한국과학기술원

Inventor： 조규성 ,  임경택 ,  김지수 ,  조민식

IPC: G01T1/29 ,  A61B6/03

Abstract: 대면적센서, 상기대면적센서위측면에픽셀화되어배치된복수개의섬광체를포함하는섬광체어레이, 및상기복수개의섬광체각각의일 면에상기섬광체당 한개씩부착되는소면적센서를포함하며, 상기섬광체어레이에접촉되는상기대면적센서의면적은상기섬광체어레이의면적보다작도록되어있는, 양전자방출단층영상장치용검출기를공개한다.

公开(公告)号：KR1020180078037A

公开(公告)日：2018-07-09

申请号：KR1020160182994

申请日：2016-12-29

Applicant: 한국과학기술원

Inventor： 조규성 ,  임경택 ,  김지수 ,  조민식

IPC: G01T1/29 ,  A61B6/03

CPC classification number: G01T1/2985 ,  A61B6/037

Abstract: 대면적센서, 상기대면적센서위측면에픽셀화되어배치된복수개의섬광체를포함하는섬광체어레이, 및상기복수개의섬광체각각의일 면에상기섬광체당 한개씩부착되는소면적센서를포함하며, 상기섬광체어레이에접촉되는상기대면적센서의면적은상기섬광체어레이의면적보다작도록되어있는, 양전자방출단층영상장치용검출기를공개한다.

公开(公告)号：KR100838713B1

公开(公告)日：2008-06-16

申请号：KR1020070010186

申请日：2007-01-31

Applicant: 한국생명공학연구원 ,  한국과학기술원

Inventor： 최원재 ,  김지수 ,  이도현 ,  구덕본 ,  박제균 ,  이경광

IPC: C12Q1/00

CPC classification number: G01N33/48707 ,  G01N27/447 ,  G01N33/5005

Abstract: A method for selecting oocytes using a chip having an electrode substrate for dielectrophoresis is provided to select healthy oocytes more rapidly and accurately by movement of the oocytes in accordance with intracellular characteristics and treat a large number of the oocytes simultaneously, thereby being used to a field related to in vitro fertilization or blastocyst effectively. A chip for selecting oocytes of a mammal using dielectrophoresis comprises a substrate where at least one pair of electrodes is deposited and is characterized in that a space including an interval between two of the electrodes on the substrate is filled with dielectric medium. A method for selecting the oocytes comprises the steps of: (a) arranging the oocytes at a starting point without applying alternating electric field thereto on the chip; (b) applying alternating electric filed onto the chip for a constant time to force healthy oocytes to be moved to a protrusion of the chip by electrical force including dielectrophoresis, thereby separating the healthy oocytes from unhealthy oocytes; and (c) recovering the healthy oocytes selectively. Further, the electrodes are made of Au or Cr, and the substrate is glass, plastic or PCB(printed circuit board).

Abstract translation: 提供了使用具有用于介电电泳的电极基板的芯片来选择卵母细胞的方法，以便根据细胞内特征，通过卵母细胞的移动更迅速和准确地选择健康的卵母细胞，同时处理大量的卵母细胞，从而用于田间 与体外受精或囊胚有关。 使用介电电泳选择哺乳动物的卵母细胞的芯片包括其中沉积至少一对电极的基底，其特征在于，包含基底上两个电极之间的间隔的空间用电介质填充。 选择卵母细胞的方法包括以下步骤：（a）在起始点排列卵母细胞而不在芯片上施加交变电场; （b）将交替电场施加到芯片上恒定时间，以通过包括介电电泳的电力将健康的卵母细胞移动到芯片的突起，从而将健康的卵母细胞与不健康的卵母细胞分离; 和（c）选择性地恢复健康的卵母细胞。 此外，电极由Au或Cr制成，并且基板是玻璃，塑料或PCB（印刷电路板）。