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公开(公告)号：WO2018169289A1
公开(公告)日：2018-09-20
申请号：PCT/KR2018/002950
申请日：2018-03-13
Applicant: 한국과학기술원
Abstract: 본 발명은 광섬유 레이저 발생장치에 관한 것으로, 파장이 불연속적으로 변화하는 능동 모드 잠금된 광섬유 레이저 발생장치에 관한 것이다.
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公开(公告)号：WO2016204494A1
公开(公告)日：2016-12-22
申请号：PCT/KR2016/006322
申请日：2016-06-15
IPC: C12N15/873
CPC classification number: C12N15/873
Abstract: 본 발명은 금 나노선을 이용하여 생물학적 물질을 수정란의 핵내로 전달하는 방법에 관한 것이다. 본 발명에 의하면, 수정란 세포를 손상시키지 않으면서 생물학적 물질의 양이나 전달시간 등 전달조건의 정밀한 제어에 의해 전달효율을 극대화시킬 뿐만 아니라, 모자이크 현상없이 모든 할구에서 외래 유전자의 발현이 가능하기 때문에, 형질전환동물의 제작에 유용하게 이용될 수 있다.
Abstract translation: 本发明涉及使用金纳米线将生物材料输送到受精卵的细胞核中的方法。 根据本发明，通过精确地控制输送条件，例如生物材料的量或输送时间，同时受精的卵细胞不被损坏，并且外来基因可以在没有 马赛克现象，因此本发明可以有利地用于转基因动物的制造。
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公开(公告)号：KR1020160148913A
公开(公告)日：2016-12-27
申请号：KR1020150085702
申请日：2015-06-17
IPC: C12N15/873 , C12N15/89 , C12N13/00 , C01G7/00
CPC classification number: C12N15/873
Abstract: 본발명은금 나노선을이용하여생물학적물질을수정란의핵내로전달하는방법에관한것이다. 본발명에의하면, 수정란세포를손상시키지않으면서생물학적물질의양이나전달시간등 전달조건의정밀한제어에의해전달효율을극대화시킬뿐만아니라, 모자이크현상없이모든할구에서외래유전자의발현이가능하기때문에, 형질전환동물의제작에유용하게이용될수 있다.
Abstract translation: 本发明涉及使用金纳米线将生物材料输送到受精卵的细胞核中的方法。 根据本发明，通过精确地控制输送条件，例如生物材料的量或输送时间，同时受精的卵细胞不被损坏，并且外来基因可以在没有 马赛克现象，因此本发明可以有利地用于转基因动物的制造。
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5.发明公开
公开(公告)号：KR1020120055818A
公开(公告)日：2012-06-01
申请号：KR1020100117228
申请日：2010-11-24
Applicant: 한국과학기술원
IPC: C01B21/082 , B82B1/00 , B82B3/00 , G01N21/64
CPC classification number: C01B21/0828 , C01P2004/30 , C01P2004/64 , G01N21/64
Abstract: PURPOSE: The synthesis of carbon nitride in the form of a three-dimensional cubical shaped nano-structure and a method for selectively detecting copper ions using the same are provided to easily detect copper ions in an aqueous solution and under physiological conditions by implementing selective optical detection with respect to the copper ions based on fluorescent measurement. CONSTITUTION: Carbon nitride is synthesized by using three-dimensional cubical shaped mesoporous silica. The carbon nitride is obtained by the following: a cyanamide aqueous solution is introduced into a three dimensional cubical shaped mesoporous silica template; a centrifugal separation process and a drying process are implemented; the dried material is plasticized; the plasticized material is treated with ammonium hydrogen fluoride and is dried; and the silica template is eliminated.
Abstract translation: 目的：提供三维立方体状纳米结构形式的氮化碳的合成和使用其的铜离子的选择性检测方法，以便通过实施选择性光学来容易地检测水溶液中的铜离子和生理条件下的铜离子 基于荧光测量相对于铜离子的检测。 构成：使用三维立方形介孔二氧化硅合成碳氮化物。 通过以下方法获得氮化碳：将氰胺水溶液引入三维立方形介孔二氧化硅模板中; 执行离心分离过程和干燥过程; 干燥的材料被塑化; 将该增塑材料用氟化氢铵处理并干燥; 并消除二氧化硅模板。
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Patent Agency Ranking
公开(公告)号：KR100924514B1
公开(公告)日：2009-11-02
申请号：KR1020070062935
申请日：2007-06-26
Applicant: 한국과학기술원
IPC: G01N27/26 , G01N33/561 , G01N33/00
Abstract: 본 발명은 단백질 시료의 수평 흐름에 직교하는 방향으로 전기장을 형성시키는 전극이 연결된 자유흐름 전기영동 챔버를 포함하며, 상기 전기영동 챔버의 양 말단에 각각 주입구 및 배출구가 연결된 것을 특징으로 하는 단백질 시료의 미세전기탈염장치, 이를 포함하는 랩온어칩 및 이들을 적용하는 방법에 관한 것이다. 본 발명에 의하면, 별도의 전처리 과정이 없이 미세전기탈염장치 또는 상기 미세전기탈염장치를 포함하는 랩온어칩 상에서 적은 양의 단백질 시료를 사용하면서도, 단시간에 효율적으로 단백질로부터 염을 제거할 수 있으므로, 고속처리, 고순도 및 높은 재현성으로 원하는 시료의 분석을 수행할 수 있는 효과가 있다.
미세전기탈염장치, 자유흐름 전기영동 챔버, 랩온어칩, 단백질 정제, 전기장-
公开(公告)号：KR1020090066958A
公开(公告)日：2009-06-24
申请号：KR1020070134710
申请日：2007-12-20
Applicant: 한국과학기술원
IPC: C12P7/40
Abstract: A method for isolating and purifying succinic acid through the crystallization of medium is provided to perform the direct crystallization without pre-treatment and purify the succinic acid of high purity and yield. A method for purifying succinic acid from medium of microorganism which generates succinic acid comprises: a step of concentrating medium in which the microorganism is removed; a step of oxidizing the medium at pH 1.0~3.0 with hydrochloric acid or sulfuric acid; and a step of cooling the oxidized medium at 2-20°C and collecting a crystallized succinic acid. The method further comprises a step of decolorizing the medium with 1.8~2.5%(w/v) of active carbon before the step of concentrating. The microorganism is a Mannheimia succiniciproducens PALK.
Abstract translation: 提供通过介质结晶分离和纯化琥珀酸的方法，以进行直接结晶而无需预处理，并纯化高纯度的琥珀酸和产率。 从产生琥珀酸的微生物培养基中纯化琥珀酸的方法包括：将微生物除去的培养基浓缩的步骤; 用盐酸或硫酸氧化pH为1.0〜3.0的培养基的步骤; 以及在2-20℃下冷却氧化介质并收集结晶的琥珀酸的步骤。 该方法还包括在浓缩步骤之前用1.8-2.5％（w / v）的活性炭对介质进行脱色的步骤。 微生物是一种Mannheimia succiniciproducens PALK。
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8.发明授权
公开(公告)号：KR100792620B1
公开(公告)日：2008-01-09
申请号：KR1020070017578
申请日：2007-02-21
Applicant: 한국과학기술원
CPC classification number: B01J20/22 , B01J20/103 , B01J20/32 , C01B33/00
Abstract: A mesoporous silica SBA-15 grafted with amine and a method of purifying succinic acid more efficiently and economically by using the same are provided to adsorb selectively impure organic acids generated together with succinic acid by strains in the fermentation process. A mesoporous silica SBA-15 grafted with amine is used as an adsorbent of impure organic acids in the purification process of succinic acid. The amine is a primary amine, a secondary amine, or a tertiary amine. The primary amine is 3-aminopropyltriethoxysilane, the secondary amine is N-methylaminopropyltrimethoxysilane, and the tertiary amine is 3-(N,N-dimethylaminopropyl)trimethoxysilane. A purification method of succinic acid comprises adsorbing and removing impure organic acids using the mesoporous silica SBA-15 grafted with amine as an adsorbent for adsorbing impure organic acids. The purification method comprises performing the adsorption process in the pH range of 2.0 to 2.5.
Abstract translation: 提供接枝有胺的介孔二氧化硅SBA-15和通过使用它们更有效和经济地纯化琥珀酸的方法，以便在发酵过程中通过菌株选择性地不纯生成与琥珀酸一起生成的有机酸。 在琥珀酸的纯化过程中，使用接枝有胺的介孔二氧化硅SBA-15作为不纯的有机酸的吸附剂。 胺是伯胺，仲胺或叔胺。 伯胺是3-氨基丙基三乙氧基硅烷，仲胺是N-甲基氨基丙基三甲氧基硅烷，叔胺是3-（N，N-二甲基氨基丙基）三甲氧基硅烷。 琥珀酸的纯化方法包括使用接枝有胺的介孔二氧化硅SBA-15吸附和除去不纯的有机酸作为吸附不纯的有机酸的吸附剂。 净化方法包括在2.0至2.5的pH范围内进行吸附过程。
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公开(公告)号：KR1020120017892A
公开(公告)日：2012-02-29
申请号：KR1020100080827
申请日：2010-08-20
Applicant: 한국과학기술원
CPC classification number: H03H3/02 , H03H9/15 , H03H9/17 , H03H9/24 , H03H2009/02173
Abstract: PURPOSE: A film bulk acoustic resonator device and a manufacturing method thereof are provided to improve resonance properties of the film bulk acoustic resonator device using a zinc oxide piezoelectric layer deposited in a mixed gas atmosphere of argon gas and nitrogen gas. CONSTITUTION: A film bulk acoustic resonator(FBAR) device includes a substrate(100), a lower electrode(102), a piezoelectric thin film(104), and an upper electrode(106). The FBAR device has a structure in which the upper electrode and the lower electrode are arranged on the substrate. The piezoelectric thin film is deposited between the lower electrode and the upper electrode. The substrate is comprised of elements such as silicon, GaAs, and etc. The piezoelectric thin film is made of a dielectric layer which includes zinc oxide or aluminum-nitride. A sputtering technique, a CVD(Chemical Vapor Deposition) technique, MBE(Molecular Beam Epitaxial) technique, or etc. is used as a piezoelectric thin film deposition technique.
Abstract translation: 目的：提供一种薄膜体声波谐振器及其制造方法，以改善使用沉积在氩气和氮气的混合气体气氛中的氧化锌压电层的薄膜体声波谐振器的谐振特性。 构成：薄膜体声波谐振器（FBAR）器件包括衬底（100），下电极（102），压电薄膜（104）和上电极（106）。 FBAR器件具有将上电极和下电极配置在基板上的结构。 压电薄膜沉积在下电极和上电极之间。 衬底由诸如硅，GaAs等的元件组成。压电薄膜由包括氧化锌或氮化铝的电介质层制成。 使用溅射技术，CVD（化学气相沉积）技术，MBE（分子束外延）技术等作为压电薄膜沉积技术。
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公开(公告)号：KR1020070122415A
公开(公告)日：2007-12-31
申请号：KR1020070062941
申请日：2007-06-26
Applicant: 한국과학기술원
IPC: G01N33/50 , G01N33/48 , G01N33/483
Abstract: A micro-mixing device of samples is provided to simplify the device and improve the mixing efficiency and rapidness, so that the device realizes various lab-on-a-chips in combination with various micro-analysis devices. A micro-mixing device of samples comprises: a sample-mixing chamber equipped with a magnetic disc which is operated by the magnetic field; and an inlet and an outlet which are connected to both ends of the sample-mixing chamber, respectively, wherein the device further comprises an analysis chamber for analysis of mixing efficiency of samples between the sample-mixing chamber and the outlet and the magnetic disc is impregnated into a polymer film of polydimethyl siloxane. A lab-on-a-chip contains the micro-mixing device of samples and a solid phase extraction device connected to the micro-mixing device, which is packed with polymer solid phase-extracting agents through in-situ polymerization.
Abstract translation: 提供样品的微混合装置以简化装置并提高混合效率和快速性，使得该装置与各种微分析装置结合实现各种实验室上的芯片。 样品的微混合装置包括：装有由磁场操作的磁盘的样品混合室; 以及分别与样品混合室的两端连接的入口和出口，其中所述装置还包括分析室，用于分析样品混合室和出口之间的样品的混合效率，并且磁盘为 浸渍在聚二甲基硅氧烷的聚合物膜中。 芯片实验室包含样品的微混合装置和连接到微混合装置的固相萃取装置，其通过原位聚合装入聚合物固相萃取剂。
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