Abstract:
Provided in the present invention is a composition for preventing, alleviating, improving symptoms of, or treating insulin resistance and type II diabetes containing capsiate as an active ingredient. The composition of the present invention shows an excellent effect of preventing and treating insulin resistance and type II diabetes by increasing the secretion of insulin and insulin sensitivity, reducing the insulin resistance, and increasing the proliferation of pancreatic β cells.
Abstract:
본 발명은 유자 추출물을 유효성분으로 포함하는 기억력 및 학습 능력 증진용 조성물 및 인지기능장애 예방 및 치료용 조성물을 제공한다. 본 발명은 Tau 단백질의 인산화를 억제시키고 뇌조직의 아밀로이드 축적을 억제시키며 인슐린 저항성을 감소시킴으로써 인지기능 장애를 예방하는 효과를 갖는다. 본 발명은 신경세포를 보호 및 손상의 예방 효과를 통하여 기억력 및 학습 능력을 증진시킬 수 있을 뿐 만 아니라 인지기능장애로 질환을 예방 및 치료 할 수 있는 효능을 발휘한다. 해마에서의 아밀로이드의 축적은 체내 인슐린 저항성 증가시키고 간에서의 인슐린 신호전달을 약화시키는데 유자추출물은 이러한 체내 인슐린 저항성의 악화를 방지하는 역할을 한다. 또한, 본 발명은 기억력 및 학습 능력의 증진 효능, 또는 인지기능장애를 예방 및 치료 효능을 가지는 유자 추출물의 의약 및 식품으로서의 기초적인 자료를 제공한다.
Abstract:
The present invention provides a pharmaceutical composition comprising bean paste fermented by inoculating licheniformis to boiled beans or an extract thereof as an active ingredient for preventing and treating dementia. The fermented bean paste according to the present invention prevents accumulation of β-amyloid in the hippocampal CA1 region and has effects of alleviating cognitive impairments of a dementia animal model and anti-dementia effect, thereby can be usefully used as a composition for preventing and treating dementia.
Abstract:
메주 추출물을 유효성분으로 함유하는 항당뇨제 및 당뇨 개선용 건강기능식품이 제공된다. 본 발명의 항당뇨제 및 건강기능식품은 생체 내에서 혈당을 떨어뜨려줄 뿐만 아니라, 인슐린 저항성을 감소시킴으로써 당뇨병 특히 인슐린 저항성을 갖는 제2형 당뇨병의 치료 및 개선에 유효하며, 아주 오래전부터 아무런 부작용 없이 사용되어온 메주로부터 제조되므로, 안전성 면에서 매우 효과적이다.
Abstract:
PURPOSE: A therapeutic agent containing complex lignan for treating type 2 diabetes is provided to suppress blood glucose and to reduce insulin resistance. CONSTITUTION: A therapeutic agent for treating type 2 diabetes contains complex lignin of 3-5 weight parts of schizandrin, 2-4 weight parts of gomisin A, and 0.5-1.5 weight parts of angeloylgomisin H. The schizandrin is schizandrin A, schizandrin B, schizandrin C, or mixture thereof. The complex lignin additionally contains schizandrol, angeloylgomisin O, angeloylgomisin P, epigomisin, pregomoisin, or deoxyschizandrin lignan. A health food for treating type 2 diabetes contains the complex lignan as an active ingredient. A method for reducing blood glucose comprises a step of administering the complex lignan to a subject by oral or intravenous injection, intranasal inhalation, or intramuscular or intraperitoneal administration.
Abstract:
PURPOSE: A health functional food for anti-diabetes and diabetes treatment containing meju extract is provided to lower blood glucose in vivo and to treat and relieve type 2 diabetes without side effect. CONSTITUTION: An anti-diabetes agent contains meju extract as active ingredient. The extract includes water extract or C1-C4 low carbon number alcohol extract. A health function al food for treating acne contains the meju extract as an active ingredient. The extract is water.
Abstract:
The present invention provides a composition for preventing, relieving, curing, and treating insulin resistance and type 2 diabetes comprising capsiate as an active ingredient. The composition of the present invention improves insulin secretion and insulin sensitivity, reduces insulin resistance, and improves the proliferation of pancreatic β-cell for offering an excellent effect on preventing and treating insulin resistance and type 2 diabetes. The present invention provides a pharmaceutical composition for preventing, relieving, curing, and treating insulin resistance and type 2 diabetes comprising capsiate as an active ingredient. The present invention provides a food composition for preventing, relieving, and treating insulin resistance and type 2 diabetes comprising capsiate as an active ingredient.