公开(公告)号：KR100460449B1

公开(公告)日：2004-12-08

申请号：KR1020010072183

申请日：2001-11-20

Applicant: 한국화학연구원

Inventor： 심영기 ,  이기인 ,  조광님 ,  박민섭

IPC: C07C69/743

Abstract: PURPOSE: A method for preparing bifenthrin is provided, to obtain bifenthrin with the improved production yield under the milder condition by employing the thioacyl dithiophosphate as an intermediate. CONSTITUTION: The method comprises the steps of reacting the 3-(2-chloro-3,3,3-trifluoro-1-propenyl)-2,2-dimethyl cyclopentane carboxylic acid alkyl ester represented by the formula 2 with the dithiophosphate represented by the formula 3 to prepare the thioacyl dithiophosphate represented by the formula 4; and reacting the thioacyl dithiophosphate of the formula 4 with the 2-methyl-biphenyl-3-yl-methanol represented by the formula 5 to prepare the bifenthrin represented by the formula 1, wherein R1 and R2 are an alkyl group of C1-C6, respectively. Preferably the first step is carried out with stirring the mixture in the presence of an amine base; and the second step is carried out in the presence of an amine base at a room temperature.

Abstract translation: 目的：提供一种制备联苯菊酯的方法，通过使用硫代酰基二硫代磷酸酯作为中间体，在较温和的条件下获得具有提高的产量的联苯菊酯。 构成：该方法包括使由式2表示的3-（2-氯-3,3,3-三氟-1-丙烯基）-2,2-二甲基环戊烷羧酸烷基酯与由式2表示的二硫代磷酸酯 用于制备由式4表示的硫代酰基二硫代磷酸酯的式3; 并使式4的硫代酰基二硫代磷酸酯与式5代表的2-甲基 - 联苯-3-基 - 甲醇反应，以制备式1代表的联苯菊酯，其中R1和R2为C1-C6烷基， 分别。 优选地，第一步骤是在胺碱存在下搅拌混合物进行的; 第二步在室温下在胺碱存在下进行。

公开(公告)号：KR1020030041410A

公开(公告)日：2003-05-27

申请号：KR1020010072183

申请日：2001-11-20

Applicant: 한국화학연구원

Inventor： 심영기 ,  이기인 ,  조광님 ,  박민섭

IPC: C07C69/743

Abstract: PURPOSE: A method for preparing bifenthrin is provided, to obtain bifenthrin with the improved production yield under the milder condition by employing the thioacyl dithiophosphate as an intermediate. CONSTITUTION: The method comprises the steps of reacting the 3-(2-chloro-3,3,3-trifluoro-1-propenyl)-2,2-dimethyl cyclopentane carboxylic acid alkyl ester represented by the formula 2 with the dithiophosphate represented by the formula 3 to prepare the thioacyl dithiophosphate represented by the formula 4; and reacting the thioacyl dithiophosphate of the formula 4 with the 2-methyl-biphenyl-3-yl-methanol represented by the formula 5 to prepare the bifenthrin represented by the formula 1, wherein R1 and R2 are an alkyl group of C1-C6, respectively. Preferably the first step is carried out with stirring the mixture in the presence of an amine base; and the second step is carried out in the presence of an amine base at a room temperature.

Abstract translation: 目的：提供一种用于制备联苯菊酯的方法，通过使用硫代酰基二硫代磷酸酯作为中间体，在较温和的条件下获得具有改善的产率的联苯菊酯。 构成：该方法包括使由式2表示的3-（2-氯-3,3,3-三氟-1-丙烯基）-2,2-二甲基环戊烷羧酸烷基酯与由式2表示的二硫代磷酸酯 式3制备由式4表示的硫代酰基二硫代磷酸酯; 并使式4的硫代酰基二硫代磷酸酯与式5表示的2-甲基 - 联苯-3-基 - 甲醇反应，制备由式1表示的联苯菊酯，其中R1和R2是C1-C6烷基， 分别。 优选地，在胺基存在下搅拌混合物进行第一步骤; 第二步是在室温下在胺碱的存在下进行。