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公开(公告)号：KR1020100132256A
公开(公告)日：2010-12-17
申请号：KR1020090050984
申请日：2009-06-09
Applicant: 한국화학연구원
CPC classification number: C12Q1/6837 , C12N15/11 , C12Q2561/109
Abstract: PURPOSE: A biomarkder for confirming exposure of welding fume and a confirmation method using the same are provided to determine the exposure. CONSTITUTION: A biomarker for confirming exposure of welding fume contains a gene of which expression is increased or decreased by expression of welding fume. A microarray chip for confirming welding fume exposure comprises entire or partial oligonucleotide of biomarker gene sequence or oligonucleotide which is complementary to the oligonucleotide. A kit for confirming the exposure of welding fume has the microarray chip.
Abstract translation: 目的：提供确认焊接烟雾暴露的生物标记物和使用其的确认方法以确定曝光。 构成：用于确认焊接烟雾暴露的生物标志物含有通过焊接烟雾表达而增加或减少表达的基因。 用于确认焊接烟雾暴露的微阵列芯片包括与寡核苷酸互补的生物标记基因序列或寡核苷酸的全部或部分寡核苷酸。 用于确认焊接烟雾暴露的试剂盒具有微阵列芯片。
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公开(公告)号：KR1020080061335A
公开(公告)日：2008-07-02
申请号：KR1020080017278
申请日：2008-02-26
CPC classification number: A61K8/466 , A61K8/411 , A61K2800/4324 , A61Q5/10
Abstract: A composition comprising hair dye is provided to reduce skin irritation and hair damage after dyeing by using no harmful aromatic amine, improve convenience of use as compared with the conventional permanent hair coloring products, and enhance washability and coloring ability. A hair dyeing composition comprises 1-10 wt.% of thickening agent, 1-20 wt.% of penetrant, 0.01-5 wt.% of reactive dye having a vinylsulfone group, represented by the formula(2) in which M is an alkali metal ion such as H, Li, Na or K, and a remaining amount of water, and further comprises 1-5 wt.% of a pH regulating agent or a reducing agent for reducing a -S-S bond, wherein under acidic condition, the reactive group of dye forms a covalent bond with a reactive group of hair keratin, thereby coloring the hair keratin.
Abstract translation: 提供一种包含染发剂的组合物，通过使用无有害芳香胺，可以减轻染色后的皮肤刺激和毛发损伤，提高使用方便性，与常规的永久性着色产品相比，提高了洗涤性和着色能力。 染发组合物包含1-10重量％的增稠剂，1-20重量％的渗透剂，0.01-5重量％的具有乙烯基砜基的活性染料，由式（2）表示，其中M是 碱金属离子如H，Li，Na或K和剩余量的水，还包含1-5重量％的pH调节剂或还原-SS键的还原剂，其中在酸性条件下， 染料的反应性基团与毛发角蛋白的反应性基团形成共价键，从而着色头发角蛋白。
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公开(公告)号：KR1020080060480A
公开(公告)日：2008-07-02
申请号：KR1020060134625
申请日：2006-12-27
CPC classification number: A61K8/463 , A61K8/411 , A61K2800/4324 , A61Q5/10
Abstract: A hair dyeing composition is provided to inhibit skin irritation by removing use of harmful components, improve convenience of use, coloring ability and washability, express various colors, and increase maintenance of color. A hair dyeing composition comprises 1-10 wt.% of thickening agent, 1-20 wt.% of penetrant, 0.01-5 wt.% of reactive dye with a vinylsulfone group, represented by the formula(1), (2), (3), (4) or (5) in which M is alkali metal ion such as H, Li, Na or K, and a remaining amount of water, and further comprises 1-5 wt.% of pH regulator and a reducing agent for reducing -S-S bond of hair keratin. A method for manufacturing the hair dyeing composition comprises the steps of: (a) dissolving the thickening agent in water to obtain a mixture; (b) adding the penetrant into the mixture to form a base solution; and (c) adding the reactive dye with a vinylsulfone group into the base solution.
Abstract translation: 提供一种染发组合物，通过去除使用有害成分，提高使用方便性，着色能力和洗涤性，表现各种颜色，增加颜色的维持来抑制皮肤刺激。 染发组合物包含1-10重量％的增稠剂，1-20重量％的渗透剂，0.01-5重量％的由乙烯基砜基组成的活性染料，由式（1），（2）， （3），（4）或（5）其中M为碱金属离子如H，Li，Na或K，剩余量为水，还包含1-5重量％的pH调节剂和还原剂 减少头发角蛋白-SS键的药剂。 毛染染色组合物的制造方法包括以下步骤：（a）将增稠剂溶解于水中得到混合物; （b）将渗透剂加入到混合物中以形成碱溶液; 和（c）将具有乙烯砜基团的活性染料加入到碱溶液中。
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公开(公告)号：KR101093726B1
公开(公告)日：2011-12-19
申请号：KR1020090050984
申请日：2009-06-09
Applicant: 한국화학연구원
Abstract: 본 발명은 용접 흄(welding fume)에 대한 노출 여부 확인용 바이오마커 및 이를 이용한 확인 방법에 관한 것으로, 구체적으로 폐질환을 유발하는 용접 흄의 노출 또는 노출 후 회복에 의해 특이적으로 유전자 발현이 증가 또는 감소하는 바이오마커, 및 이를 이용한 용접 흄에 대한 노출 또는 노출역(歷) 여부를 확인하는 방법에 관한 것이다. 본 발명의 바이오마커가 집적된 DNA 마이크로어레이 칩은 인간의 폐에 대한 용접 흄 노출 또는 노출역(歷) 여부를 판정하는데 유용하게 사용될 수 있으며, 용접 흄에 의한 폐질환 유발 및 회복 기작을 규명하는 도구로 이용될 수 있다.
용접 흄, 폐질환, 바이오마커, DNA 마이크로어레이 칩, 키트.-
公开(公告)号：KR100884894B1
公开(公告)日：2009-02-23
申请号：KR1020060134625
申请日：2006-12-27
Abstract: 반응성 염료를 포함하는 새로운 염모제와 그 제조방법이 개시된다. 이러한 본 발명의 염모제는 점증제, 침투제 및 비닐설폰 반응기를 가지는 반응성 염료를 포함한다. 본 발명에 따른 반응성 염모제 조성물은 산성조건에서 염료의 반응기와 헤어케라틴의 반응기가 화학반응을 하여 공유결합을 형성하여 헤어케라틴을 염색한다. 피부자극성이 없고, 사용이 비교적 간편하다. 또한 발색력이 우수하고, 다양한 색상을 표현할 수 있다. 또한 수세성이 좋고, 비교적 긴 지속력을 갖는다.
비닐설폰 반응기, 점증제, 침투제, 환원제-
Patent Agency Ranking
公开(公告)号：KR100844227B1
公开(公告)日：2008-07-04
申请号：KR1020080017278
申请日：2008-02-26
Abstract: 반응성 염료를 포함하는 새로운 염모제와 그 제조방법이 개시된다. 이러한 본 발명의 염모제는 점증제, 침투제 및 비닐설폰 반응기를 가지는 반응성 염료를 포함한다. 본 발명에 따른 반응성 염모제 조성물은 산성조건에서 염료의 반응기와 헤어케라틴의 반응기가 화학반응을 하여 공유결합을 형성하여 헤어케라틴을 염색한다. 피부자극성이 없고, 사용이 비교적 간편하다. 또한 발색력이 우수하고, 다양한 색상을 표현할 수 있다. 또한 수세성이 좋고, 비교적 긴 지속력을 갖는다.
비닐설폰 반응기, 점증제, 침투제, 환원제-
公开(公告)号：KR1020080061336A
公开(公告)日：2008-07-02
申请号：KR1020080017284
申请日：2008-02-26
CPC classification number: A61K8/466 , A61K8/411 , A61K2800/4324 , A61Q5/10
Abstract: A hair dyeing composition comprising a pink reactive dye is provided to minimize skin irritation and hair damage after dyeing, enhance coloring ability and maintenance ability and express various colors, especially pink color. A hair dyeing composition comprises 1-10 wt.% of thickening agent, 1-20 w.% of penetrant, 0.01-5 wt.% of a pink reactive dye having a vinylsulfone group, represented by the formula(3) in which M is a alkali metallic ion and H, Li, Na or K, and a remaining amount of water, and further comprises a reducing agent for reducing a -S-S bond of hair keratin. A method for producing the hair dyeing composition comprises the steps of: mixing water with a thickening agent; adding the penetrant into the mixture to prepare dye base; and adding a pink reactive dye having a vinylsulfone group into the dye base and mixing them. Further, the hair dyeing composition additionally comprises 1-5 wt.% of pH adjusting agent.
Abstract translation: 提供包含粉红色活性染料的染发组合物，以减少染色后的皮肤刺激和毛发损伤，增强着色能力和维持能力，并表现出各种颜色，特别是粉红色。 染发组合物包含1-10重量％的增稠剂，1-20重量％的渗透剂，0.01-5重量％的由式（3）表示的具有乙烯基砜基团的粉红色活性染料，其中M 是碱金属离子和H，Li，Na或K和剩余量的水，并且还包含用于还原毛发角蛋白的-SS键的还原剂。 一种生发染发组合物的方法，包括以下步骤：将水与增稠剂混合; 将渗透剂加入混合物中制备染料基质; 并将具有乙烯砜基的粉红色活性染料加入到染料基中并混合。 此外，染发组合物另外含有1-5重量％的pH调节剂。
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公开(公告)号：KR100830421B1
公开(公告)日：2008-05-22
申请号：KR1020070023459
申请日：2007-03-09
IPC: C09B62/002 , C09B62/006
CPC classification number: C09B62/0025 , C09B62/004 , C09B62/006 , D06P3/248
Abstract: A novel reactive dye for dyeing polyamide fiber, and a method for preparing the reactive dye are provided to improve the purity of a dye by lowering water solubility and to enhance fixation, dyeing uniformity and washing fastness. A reactive dye is represented by the formula I, wherein A1 and A2 are independently H, a methyl A reactive dye, a methoxy group, Br, Cl, a cyano group, a nitro group, a hydroxysulfonyl group, a C1-C2 alkyl sulfonyl group or a vinyl sulfonyl group; L is an amino group or an azo group; and D is a dye mother material represented by the formula VIII, IX or X. In the formula VIII, R1 is H, a C1-C2 alkyl group, an acetyl group, a benzyl group or a benzoyl group; and M is H or an alkali metal. In the formula IX, R3 is a methyl group or a hydroxycarbonyl group; X1 and X2 is H or Cl; and M is H or an alkali metal.
Abstract translation: 提供用于染色聚酰胺纤维的新型活性染料和制备活性染料的方法，以通过降低水溶性并提高固色，染色均匀性和耐洗牢度来提高染料的纯度。 活性染料由式I表示，其中A1和A2独立地为H，甲基A活性染料，甲氧基，Br，Cl，氰基，硝基，羟基磺酰基，C1-C2烷基磺酰基 基团或乙烯基磺酰基; L是氨基或偶氮基; D是由式VIII，IX或X表示的染料母体材料。在式Ⅷ中，R 1是H，C 1 -C 2烷基，乙酰基，苄基或苯甲酰基; M为H或碱金属。 在式IX中，R 3是甲基或羟基羰基; X1和X2是H或Cl; M为H或碱金属。
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公开(公告)号：KR100844226B1
公开(公告)日：2008-07-04
申请号：KR1020080017284
申请日：2008-02-26
Abstract: 반응성 염료를 포함하는 새로운 염모제와 그 제조방법이 개시된다. 이러한 본 발명의 염모제는 점증제, 침투제 및 비닐설폰 반응기를 가지는 반응성 염료를 포함한다. 본 발명에 따른 반응성 염모제 조성물은 산성조건에서 염료의 반응기와 헤어케라틴의 반응기가 화학반응을 하여 공유결합을 형성하여 헤어케라틴을 염색한다. 피부자극성이 없고, 사용이 비교적 간편하다. 또한 발색력이 우수하고, 다양한 색상을 표현할 수 있다. 또한 수세성이 좋고, 비교적 긴 지속력을 갖는다.
비닐설폰 반응기, 점증제, 침투제, 환원제-
公开(公告)号：KR1020080061339A
公开(公告)日：2008-07-02
申请号：KR1020080017294
申请日：2008-02-26
CPC classification number: A61K8/466 , A61K8/411 , A61K2800/4324 , A61Q5/10
Abstract: A method for manufacturing a hair keratin dyeing composition is provided to dye the hair keratin with minimized skin irritation and hair damage by using no components harmful to human, enhance application convenience and express various hair colors. A method for manufacturing a hair keratin dyeing composition comprises the steps of: (1) mixing 1-10 wt.% of thickening agent with water to form a mixture; (2) adding 1-20 wt.% of penetrant into the mixture to form a base solution; and (3) adding 0.01-5 wt.% of a reactive dye with a vinylsulfone group into the base solution, and optionally adding 1-5 wt.% of pH regulating agent and a reducing agent for reducing a S-S bond of hair keratin.
Abstract translation: 提供一种制造头发角蛋白染色组合物的方法，通过不使用对人体有害的组分，增强应用方便性和表现各种头发颜色，使毛发角蛋白以最小化的皮肤刺激和头发损伤进行染色。 一种毛发角蛋白染色组合物的制造方法包括以下步骤：（1）将1-10重量％的增稠剂与水混合以形成混合物; （2）将1-20重量％的渗透剂加入到混合物中以形成碱溶液; 和（3）将0.01-5重量％的具有乙烯砜基团的活性染料加入到碱溶液中，并且任选地加入1-5重量％的pH调节剂和用于还原毛发角蛋白的S-S键的还原剂。
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