公开(公告)号：KR1020100054452A

公开(公告)日：2010-05-25

申请号：KR1020080113389

申请日：2008-11-14

Applicant: 한림대학교 산학협력단 ,  (주)네추럴에프앤피

Inventor： 원무호 ,  유기연 ,  황인구 ,  리화 ,  서홍원 ,  김도훈 ,  문원국 ,  김동우

IPC: A61K31/343 ,  A61P9/10

Abstract: PURPOSE: A pharmaceutical composition containing escitalopram is provided to prevent neural cell damage in a CA1 area and to prevent or treat ischemic brain diseases. CONSTITUTION: A pharmaceutical composition for preventing or treating ischemic a brain disease contains escitalopram. Ischemic brain disease is thrombosis, embolism, transient ischemic attack, cerebral infarction, cerebral hemorrhage, subarachnoid hemorrhage, white matter dyslipidemia, or lacune. The administering of escitalopram prevents or treats ischemic brain diseases. A pharmaceutical composition for preventing or treating brain disease contains escitalopram and a pharmaceologically acceptable carrier or excipient. The pharmaceutically acceptable carrier or excipient is water, dextrin, or a saline solution. The composition is used in the form of plasters, granules, lotions, powders, syrups, liquids and solutions, aerosols, ointments, fluid extract, emulsion, suspensions, infusions, tablets, injections, capsules, or pills.

Abstract translation: 目的：提供含有依他普仑的药物组合物，以防止CA1区域的神经细胞损伤，并预防或治疗缺血性脑病。 构成：用于预防或治疗缺血性脑病的药物组合物含有依他普仑。 缺血性脑病是血栓形成，栓塞，短暂性脑缺血发作，脑梗塞，脑出血，蛛网膜下腔出血，白质血脂异常，或泪液。 依他普仑的给药预防或治疗缺血性脑病。 用于预防或治疗脑疾病的药物组合物含有依他普仑和药物学上可接受的载体或赋形剂。 药学上可接受的载体或赋形剂是水，糊精或盐水溶液。 组合物以膏药，颗粒剂，洗剂，粉剂，糖浆，液体和溶液，气溶胶，软膏，流体萃取物，乳液，悬浮液，输液，片剂，注射剂，胶囊或丸剂的形式使用。