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1.发明授权
公开(公告)号：KR100972023B1
公开(公告)日：2010-07-22
申请号：KR1020080001996
申请日：2008-01-08
Applicant: 한림대학교 산학협력단 , (주)네추럴에프앤피
Abstract: 본 발명은 흰색 감국 추출물을 유효성분으로 포함하는 허혈성 뇌혈관 질환 예방 또는 개선용 조성물에 관한 것으로, 보다 상세하게는 뇌허혈에 민감하다고 알려져 있는 뇌 해마조직 CA1 영역의 신경 손상을 효과적으로 예방할 뿐만 아니라, 인체에 무해한 흰색 감국 추출물을 유효성분으로 포함하는 허혈성 뇌혈관 질환 예방 또는 개선용 조성물에 관한 것이다.
흰색 감국, 허혈성 뇌혈관 질환, 치매, 알츠하이머-
2.发明公开
公开(公告)号：KR1020090076195A
公开(公告)日：2009-07-13
申请号：KR1020080001996
申请日：2008-01-08
Applicant: 한림대학교 산학협력단 , (주)네추럴에프앤피
Abstract: A composition for preventing or treating brain ischemia diseases, which contains white Chrysanthemum indicum Var. albescens as an active ingredient is provided to prevent nerve injury of CA1 area of brain hippocampus. A composition for preventing and treating brain ischemia diseases comprises 0.001-99.99 weight% of Chrysanthemum indicum var. albescens extract as an active ingredient. The brain ischemia diseases are cerebral infarction, cerebral hemorrhage, subarachnoid hemorrhage and white matter. The Chrysanthemum indicum var. albescens extract is isolated with 30-80% of alcohol solution of 1-5 carbon atoms. The composition further comprises a carrier, excipient, and diluents. The composition is used in a form of powder, granule, tablet, suspension, emulsion or syrup.
Abstract translation: 一种预防或治疗脑缺血疾病的组合物，其含有白菊花Var。 提供albescens作为活性成分，以防止脑海马CA1区域的神经损伤。 用于预防和治疗脑缺血疾病的组合物包含菊花变种的0.001-99.99重量％ 白花提取物作为活性成分。 脑缺血病是脑梗塞，脑出血，蛛网膜下腔出血和白质。 菊花变种 用30-80％的1-5个碳原子的醇溶液分离白鼬提取物。 组合物还包含载体，赋形剂和稀释剂。 该组合物以粉末，颗粒，片剂，悬浮液，乳剂或糖浆的形式使用。
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公开(公告)号：KR1020100054452A
公开(公告)日：2010-05-25
申请号：KR1020080113389
申请日：2008-11-14
Applicant: 한림대학교 산학협력단 , (주)네추럴에프앤피
IPC: A61K31/343 , A61P9/10
Abstract: PURPOSE: A pharmaceutical composition containing escitalopram is provided to prevent neural cell damage in a CA1 area and to prevent or treat ischemic brain diseases. CONSTITUTION: A pharmaceutical composition for preventing or treating ischemic a brain disease contains escitalopram. Ischemic brain disease is thrombosis, embolism, transient ischemic attack, cerebral infarction, cerebral hemorrhage, subarachnoid hemorrhage, white matter dyslipidemia, or lacune. The administering of escitalopram prevents or treats ischemic brain diseases. A pharmaceutical composition for preventing or treating brain disease contains escitalopram and a pharmaceologically acceptable carrier or excipient. The pharmaceutically acceptable carrier or excipient is water, dextrin, or a saline solution. The composition is used in the form of plasters, granules, lotions, powders, syrups, liquids and solutions, aerosols, ointments, fluid extract, emulsion, suspensions, infusions, tablets, injections, capsules, or pills.
Abstract translation: 目的：提供含有依他普仑的药物组合物，以防止CA1区域的神经细胞损伤，并预防或治疗缺血性脑病。 构成：用于预防或治疗缺血性脑病的药物组合物含有依他普仑。 缺血性脑病是血栓形成，栓塞，短暂性脑缺血发作，脑梗塞，脑出血，蛛网膜下腔出血，白质血脂异常，或泪液。 依他普仑的给药预防或治疗缺血性脑病。 用于预防或治疗脑疾病的药物组合物含有依他普仑和药物学上可接受的载体或赋形剂。 药学上可接受的载体或赋形剂是水，糊精或盐水溶液。 组合物以膏药，颗粒剂，洗剂，粉剂，糖浆，液体和溶液，气溶胶，软膏，流体萃取物，乳液，悬浮液，输液，片剂，注射剂，胶囊或丸剂的形式使用。
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公开(公告)号：KR1020070120330A
公开(公告)日：2007-12-24
申请号：KR1020060054946
申请日：2006-06-19
Applicant: 한림대학교 산학협력단 , (주)네추럴에프앤피
CPC classification number: A61K8/0212 , A61K8/0208 , A61K8/66 , A61Q17/00 , A61Q19/00 , Y10S514/844
Abstract: A mask pack is provided to inhibit the damage induced by UVB by increasing anti-oxidase such as manganese superoxide dismutase and glutathione peroxidase without causing any skin irritation. A mask pack for improving skin damage caused by UVB comprises 0.1-0.4 parts by weight of coenzyme Q10, 7.0-12.0 parts by weight of glycerin, 0.05-0.3 parts by weight of allantoin, 85-95 parts by weight of purified water, 0.04-0.08 parts by weight of carbomer, and 0.05-0.3 parts by weight of triethanolamine. The pack is a sheet type or a patch type.
Abstract translation: 提供面膜包以通过增加抗氧化酶如锰超氧化物歧化酶和谷胱甘肽过氧化物酶而不引起任何皮肤刺激来抑制UVB引起的损伤。 用于改善由UVB引起的皮肤损伤的口罩包含0.1-0.4重量份辅酶Q10,7.0-12.0重量份甘油，0.05-0.3重量份尿囊素，85-95重量份净化水，0.04 -0.08重量份的卡波姆和0.05-0.3重量份的三乙醇胺。 包装是纸张类型或补丁类型。
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5.发明公开
公开(公告)号：KR1020130013693A
公开(公告)日：2013-02-06
申请号：KR1020110075450
申请日：2011-07-28
Applicant: (주)네추럴에프앤피
IPC: A61K8/97 , A61K36/882 , A61Q19/00 , A61P17/00
Abstract: PURPOSE: An external use composition containing an Acorus calamus extract for preventing and treating atopic dermatitis is provided to suppress degranulation and excessive cytokine secretion. CONSTITUTION: A cosmetic composition for preventing or treating atopic dermatitis contains an Acorus calamus extract as an active ingredient. The extract is a solvent extract or essential oil. The solvent extract is prepared using water or butylenes glycol. A pharmaceutical composition for preventing or treating atopic dermatitis contains the extract as an active ingredient. An external use composition for preventing or treating atopic dermatitis contains the extract as an active ingredient. The external use composition is a cosmetic product or a medicine.
Abstract translation: 目的：提供含有用于预防和治疗特应性皮炎的Acorus菖蒲提取物的外用组合物，以抑制脱粒和过量的细胞因子分泌。 构成：用于预防或治疗特应性皮炎的化妆品组合物含有Acorus菖蒲提取物作为活性成分。 提取物是溶剂提取物或精油。 使用水或丁二醇制备溶剂提取物。 用于预防或治疗特应性皮炎的药物组合物含有提取物作为活性成分。 用于预防或治疗特应性皮炎的外用组合物含有提取物作为活性成分。 外用组合物是化妆品或药物。
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Patent Agency Ranking6.发明公开
公开(公告)号：KR1020090080855A
公开(公告)日：2009-07-27
申请号：KR1020080006854
申请日：2008-01-22
Applicant: (주)네추럴에프앤피 , 건국대학교 산학협력단
IPC: C01G23/04 , C04B35/465 , B82B3/00
Abstract: A pharmaceutical composition for treating inflammatory disease and immune disease, which contains a metal nanoparticle is provided to suppress the generation of nitrogen oxide and cytokine and inhibit the activation of COX-2. A pharmaceutical composition for treating inflammatory diseases and immune diseases comprises a metal nanoparticle as an active ingredient. The metal nanoparticle is selected from gold nanoparticle, silver nanoparticle, and gold shell nanoparticle. Anti-inflammatory mechanism depends on the concentration of metal nanoparticle. The inflammatory disease or immune disease is arthritis, sepsis, inflammatory skin disease or autoimmune disease. The composition is formulated with a drug selected among anti-histamine drug, anti-inflammatory drug, anti-cancer drug, and antibiotic.
Abstract translation: 提供含有金属纳米粒子的用于治疗炎性疾病和免疫疾病的药物组合物，以抑制氮氧化物和细胞因子的产生并抑制COX-2的活化。 用于治疗炎性疾病和免疫疾病的药物组合物包括金属纳米颗粒作为活性成分。 金属纳米颗粒选自金纳米颗粒，银纳米颗粒和金壳纳米颗粒。 抗炎机制取决于金属纳米粒子的浓度。 炎性疾病或免疫疾病是关节炎，败血症，炎性皮肤疾病或自身免疫性疾病。 该组合物用选自抗组胺药物，抗炎药物，抗癌药物和抗生素的药物配制。
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7.发明授权호두 및 연자육 추출물 및 이를 유효성분으로 함유하는스트레스 해소용 조성물 有权JUGLANS REGIA L.和NELUMBO NUCIFERA GAERTN的提取物及其包含其的无应力条件的组合物
公开(公告)号：KR100814634B1
公开(公告)日：2008-03-18
申请号：KR1020070102562
申请日：2007-10-11
Applicant: (주)네추럴에프앤피 , 한국식품연구원
CPC classification number: A61K36/52 , A23V2200/322 , A61K36/62 , A61K2236/331 , A61K2236/333 , A61K2236/51
Abstract: An extract of Juglans regia L. or a mixture of the Juglans regia L. and Nelumbo nucifera GAERTN is provided to decrease concentrations of corticosterone and MHPG-SO4(3-methoxy-4-hydroxyphenylethyleneglycol sulfate) significantly and also decrease the expression of c-fos related to neuroactivity in amygdala significantly, thereby being usefully used for relieving stress. A food composition for relieving stress comprises an extract of Juglans regia L. or a mixture of the Juglans regia L. and Nelumbo nucifera GAERTN, which is prepared by extracting the Juglans regia L. or a mixture of the Juglans regia L. and Nelumbo nucifera GAERTN with a solvent selected from the group consisting of water, C1-4 alcohol and a mixture thereof at a temperature of 20-150 deg.C for one hour to 10 days. Further, a mixing rate of the Juglans regia L. and Nelumbo nucifera GAERTN is 10:5-15.
Abstract translation: 提供胡桃核桃提取物或胡桃核桃和Nelumbo nucifera GAERTN的混合物显着降低皮质酮和MHPG-SO4（3-甲氧基-4-羟基苯基乙二醇硫酸酯）的浓度，并降低c- fos与杏仁核的神经活性有关，从而有效地用于缓解压力。 用于缓解胁迫的食物组合物包括胡桃木提取物或胡桃核桃和Nelumbo nucifera GAERTN的混合物，其通过提取胡桃木胡萝卜或胡桃木和Nelumbo nucifera的混合物制备 GAERTN，其中选自水，C 1-4醇及其混合物的溶剂，温度为20-150℃，持续1小时至10天。 此外，胡桃核桃和Nelumbo nucifera GAERTN的混合比为10:5-15。
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8.发明授权손바닥 선인장, 오리나무, 갈근 및 헛개나무의 복합생약추출물을 함유하는 숙취해소용 조성물 有权含有仙人掌indic comprising，us粳，葛根和枸杞的复方草药提取物的组合物，显示宿醉缓解活性
公开(公告)号：KR100608456B1
公开(公告)日：2006-08-02
申请号：KR1020040070265
申请日：2004-09-03
Applicant: (주)네추럴에프앤피
IPC: A23L2/38
Abstract: 본 발명은 손바닥 선인장 (
Opuntia ficus indica ), 오리나무 (
Alnus
japonica STEUD.), 갈근 (
Pueraria lobata (WILLD.), OHWI) 및 헛개나무 (
Hovenia dulcis THUNB.)로 구성된 복합생약추출물을 함유하는 숙취해소 및 간장 보호를 위한 기능성 식품 조성물에 관한 것으로서, 본 발명의 조성물은 인체에 부작용이 없으면서 알코올의 분해 작용 및 간장 보호 효과가 탁월하므로, 이를 유효성분으로 함유하는 조성물은 숙취해소 및 간장 보호를 위한 건강기능식품으로 유용하게 이용될 수 있다.
숙취해소, 복합 생약 추출물, 건강기능식품-
公开(公告)号：KR100538142B1
公开(公告)日：2005-12-21
申请号：KR1020030083416
申请日：2003-11-24
Applicant: (주)네추럴에프앤피
Abstract: 본 발명은 창포 오일을 포함하는 여드름 피부 개선용 화장료 조성물에 관한 것으로서, 본 발명의 수증기 증류법으로 추출한 창포 오일은 여드름균 (
Propionibacterium acnes )에 대한 강한 항진균 작용을 나타내므로 여드름에 의한 피부트러블의 개선 효과가 탁월할 뿐만 아니라, 피부 자극이 전혀 없으므로 여드름 피부 개선을 위한 기능성 화장료 조성물로 이용될 수 있다.-
10.发明授权대추 추출물을 유효성분으로 함유하는 허혈성 뇌혈관질환의 예방 및 치료용 조성물 有权组成包括ZIZIPHUS JUJUBA MILL的提取物。 用于预防和治疗ISCHEMIA损伤疾病的多种螺旋体
公开(公告)号：KR100757207B1
公开(公告)日：2007-09-10
申请号：KR1020060088897
申请日：2006-09-14
Applicant: (주)네추럴에프앤피
IPC: A61K36/725 , A61P9/10
CPC classification number: A61K36/725 , A23V2200/322 , A61K2236/331 , A61K2236/333
Abstract: A composition for prevention and treatment of ischemia cerebrovascular disease comprising the extract of Ziziphus jujuba MILL.(jujube) is provided to prevent damage of neuronal cells of hippocampus tissue CA1 region and inhibit apoptosis of neuronal cells without side effects. A composition for prevention and treatment of ischemia cerebrovascular disease comprises the extract of Ziziphus jujuba MILL. which is prepared by extracting with water, methanol, ethanol, butanol or a mixed solvent thereof, wherein the ischemia cerebrovascular disease is cerebral infarction, stroke, cerebral hemorrhage or subarachnoidal hemorrhage, and the composition is a pharmaceutical or health food composition formulated as powder, granule, tablet, capsule or drink.
Abstract translation: 提供一种预防和治疗缺血性脑血管病的组合物，其包含枣子提取物（枣），以防止海马组织CA1区域的神经元细胞的损伤并抑制神经元细胞的凋亡而没有副作用。 一种用于预防和治疗缺血性脑血管病的组合物，其特征在于含有枣枣的提取物。 其是通过用水，甲醇，乙醇，丁醇或其混合溶剂萃取而制备的，其中所述缺血性脑血管病是脑梗塞，中风，脑出血或蛛网膜下腔出血，并且该组合物是配制成粉末的药物或保健食品组合物， 颗粒，片剂，胶囊或饮料。
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