公开(公告)号：KR1020100054452A

公开(公告)日：2010-05-25

申请号：KR1020080113389

申请日：2008-11-14

Applicant: 한림대학교 산학협력단 ,  (주)네추럴에프앤피

Inventor： 원무호 ,  유기연 ,  황인구 ,  리화 ,  서홍원 ,  김도훈 ,  문원국 ,  김동우

IPC: A61K31/343 ,  A61P9/10

Abstract: PURPOSE: A pharmaceutical composition containing escitalopram is provided to prevent neural cell damage in a CA1 area and to prevent or treat ischemic brain diseases. CONSTITUTION: A pharmaceutical composition for preventing or treating ischemic a brain disease contains escitalopram. Ischemic brain disease is thrombosis, embolism, transient ischemic attack, cerebral infarction, cerebral hemorrhage, subarachnoid hemorrhage, white matter dyslipidemia, or lacune. The administering of escitalopram prevents or treats ischemic brain diseases. A pharmaceutical composition for preventing or treating brain disease contains escitalopram and a pharmaceologically acceptable carrier or excipient. The pharmaceutically acceptable carrier or excipient is water, dextrin, or a saline solution. The composition is used in the form of plasters, granules, lotions, powders, syrups, liquids and solutions, aerosols, ointments, fluid extract, emulsion, suspensions, infusions, tablets, injections, capsules, or pills.

Abstract translation: 目的：提供含有依他普仑的药物组合物，以防止CA1区域的神经细胞损伤，并预防或治疗缺血性脑病。 构成：用于预防或治疗缺血性脑病的药物组合物含有依他普仑。 缺血性脑病是血栓形成，栓塞，短暂性脑缺血发作，脑梗塞，脑出血，蛛网膜下腔出血，白质血脂异常，或泪液。 依他普仑的给药预防或治疗缺血性脑病。 用于预防或治疗脑疾病的药物组合物含有依他普仑和药物学上可接受的载体或赋形剂。 药学上可接受的载体或赋形剂是水，糊精或盐水溶液。 组合物以膏药，颗粒剂，洗剂，粉剂，糖浆，液体和溶液，气溶胶，软膏，流体萃取物，乳液，悬浮液，输液，片剂，注射剂，胶囊或丸剂的形式使用。

公开(公告)号：KR1020110090155A

公开(公告)日：2011-08-10

申请号：KR1020100009778

申请日：2010-02-03

Applicant: 한림대학교 산학협력단

Inventor： 유기연 ,  최정훈 ,  이충현 ,  리화 ,  황인구 ,  유시용 ,  김영섭 ,  원무호

IPC: A61K36/9064 ,  A61P9/10 ,  A61P25/28 ,  A61P25/00

CPC classification number: A61K36/9062 ,  A23V2200/322 ,  A61K2236/331

Abstract: PURPOSE: A pharmaceutical composition containing Alpinia katsumadai Hayata extract is provided to effectively prevent nerve cell injury of brain hippocampus CA1 region. CONSTITUTION: A pharmaceutical composition for preventing and treating cerebral ischemic nervous diseases contains 0.001-99.99 weight% of Alpinia katsumadai Hayata extract as an active ingredient. The extract is isolated using water or alcohol. A food composition for preventing and treating cerebral ischemic nervous diseases contains Alpinia katsumadai Hayata extract as an active ingredient. The food composition is a food additives or beverage.

Abstract translation: 目的：提供含有高山ai草提取物的药物组合物，有效预防脑海马CA1区神经细胞损伤。 构成：用于预防和治疗脑缺血性神经疾病的药物组合物含有0.001-99.99重量％的山楂提取物作为活性成分。 使用水或酒精分离提取物。 用于预防和治疗脑缺血性神经疾病的食物组合物含有作为活性成分的高山猕猴桃提取物。 食品组合物是食品添加剂或饮料。