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    NEGATIVE PRESSURE WOUND THERAPY ARTICLE WITH FEATURES
    1.
    发明申请
    NEGATIVE PRESSURE WOUND THERAPY ARTICLE WITH FEATURES 审中-公开
    负压伤口治疗文章与功能

    公开(公告)号：WO2018005275A1

    公开(公告)日：2018-01-04

    申请号：PCT/US2017/038939

    申请日：2017-06-23

    Applicant: 3M INNOVATIVE PROPERTIES COMPANY

    Inventor： MCNULTY, Amy K. ,  FITZSIMONS, Robert T. Jr. ,  HALVERSON, Kurt J. ,  BAKER, Bryan A. ,  NINKOVIC, Jana ,  LIU, Jie ,  DAI, Minghua ,  ZHANG, Wei ,  SGOLASTRA, Federica

    IPC: A61F13/00 ,  A61M27/00

    Abstract: An article, including a network of interconnected polymeric strands; wherein each of the interconnected polymeric strands has a first surface adapted to contact a tissue site; wherein at least one of the interconnected polymeric strand has a plurality of features extending from the first surface of the interconnected polymeric strands; wherein at least one of the interconnected polymeric strands is non-linear; and a plurality of openings between adjacent polymeric strands; wherein the article is a negative pressure wound therapy article.

    Abstract translation: 一篇文章，包括互连聚合物股线的网络; 其中每个互连聚合物股线具有适于接触组织部位的第一表面; 其中所述互连聚合物股线中的至少一个具有从所述互连聚合物股线的所述第一表面延伸的多个特征; 其中所述互连聚合物股线中的至少一个是非线性的; 和相邻聚合物股线之间的多个开口; 其中该制品是负压伤口治疗制品。

    FIBRIN COMPOSITION, METHOD AND WOUND ARTICLES
    4.
    发明申请
    FIBRIN COMPOSITION, METHOD AND WOUND ARTICLES 审中-公开
    FIBRIN组合物，方法和创新文章

    公开(公告)号：WO2016160541A1

    公开(公告)日：2016-10-06

    申请号：PCT/US2016/024141

    申请日：2016-03-25

    Applicant: 3M INNOVATIVE PROPERTIES COMPANY

    Inventor： BJORK, Jason W. ,  YOUNG, Alexi J. ,  BEEN, Raha A. ,  NINKOVIC, Jana ,  BAKER, Bryan A.

    IPC: A61L24/10

    CPC classification number: A61L26/008 ,  A61F13/0259 ,  A61F2013/00089 ,  A61F2013/00655 ,  A61F2013/00676 ,  A61F2013/00706 ,  A61L24/106 ,  A61L26/0042 ,  A61L26/0071

    Abstract: A method of forming a fibrin hydrogel composition is described. The method comprises forming an aqueous solution comprising fibrinogen, fibrin-forming enzyme, and a fibrin hydrogel forming salt. The fibrin hydrogel forming salt concentration is greater than or equal to the threshold concentration to form a fibrin hydrogel. The method further comprises reducing the salt concentration below the threshold concentration to form a fibrin hydrogel. In some embodiments, the aqueous solution further comprises a plasticizer. A fibrin composition is also described comprising a fibrin hydrogel having a fibrin concentration ranging from 0.1 to 10 wt-%; and a fibrin hydrogel forming salt. The fibrin hydrogel forming salt has a concentration less than a threshold concentration to form the fibrin hydrogel. The fibrin hydrogel or dehydrated fibrin hydrogel can be in various physical forms such a sheet, foam, or plurality of pieces. Also described are methods of forming a fibrin article, wound dressings and a method of treatment of a wound.

    Abstract translation: 描述了形成纤维蛋白水凝胶组合物的方法。 该方法包括形成包含纤维蛋白原，纤维蛋白形成酶和纤维蛋白水凝胶形成盐的水溶液。 纤维蛋白水凝胶形成盐浓度大于或等于阈值浓度以形成纤维蛋白水凝胶。 该方法还包括将盐浓度降低到阈值浓度以下以形成纤维蛋白水凝胶。 在一些实施方案中，水溶液还包含增塑剂。 还描述了纤维蛋白组合物，其包含纤维蛋白浓度范围为0.1至10重量％的纤维蛋白水凝胶; 和纤维蛋白水凝胶形成盐。 纤维蛋白水凝胶形成盐的浓度小于阈值浓度以形成纤维蛋白水凝胶。 纤维蛋白水凝胶或脱水纤维蛋白水凝胶可以是各种物理形式，例如片，泡沫或多个片。 还描述了形成纤维蛋白制品，伤口敷料和伤口治疗方法的方法。

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