Abstract:
A device for growing microorganisms. The device can include a self-supporting, water-proof substrate having an inner-facing surface and an outer-facing surface; a cover sheet having an inner-facing surface and an outer-facing surface, the cover sheet adhered to at least a portion of the substrate; a microstructured surface on the inner-facing surface of the coversheet, wherein the microstructured surface comprises a plurality of microstructures; a substantially dry, gelling agent and a substantially dry, microbial growth nutrient composition disposed on the microstructured surface of the microstructured film or on a portion of the inner-facing surface of the substrate.
Abstract:
The present disclosure provides articles including an adhesive layer; a film layer bonded to the adhesive layer having a microstructured surface including numerous capillary channels; and a cover layer disposed on the capillary channels and attached to the adhesive layer. The adhesive layer is hydrophobic and includes an aperture for fluid (e.g., sweat) collection from a skin surface. The film layer also includes an aperture that overlaps the adhesive layer aperture to direct collected fluid to the capillary channels of the microstructured surface, which have a hydrophilic surface. Optionally at least one indicator chemistry can be present in the channels to facilitate optical (e.g., visual) determination of total fluid volume and/or concentration of at least one analyte in the fluid as a function of time.
Abstract:
Films and articles are described comprising a microstructured surface having an array of peak structures and adjacent valleys. For improved cleanability, the valleys preferably have a maximum width ranging from 10 microns to 250 microns and the peak structures have a side wall angle greater than 10 degrees. The peak structures may comprise two or more facets such as in the case of a linear array of prisms or an array of cube-corners elements. The facets form continuous or semi-continuous surfaces in the same direction. The valleys typically lack intersecting walls. Also described are methods of making and methods of use. The microstructured surface of the article can be prepared by various microreplication techniques such as coating, injection molding, embossing, laser etching, extrusion, casting and curing a polymerizable resin; and bonding microstructured film to a surface or article with an adhesive.
Abstract:
A fibrin-coated wound dressing article having a flexible film layer, a pressure-sensitive adhesive layer disposed on the flexible film layer, and a fibrin powder layer disposed on a surface of the pressure-sensitive adhesive layer opposite the flexible film layer. Methods of making and using fibrin-coated wound dressing articles are included.
Abstract:
A biological sterilization indicator device is provided. The device comprises a body, a plurality of test microorganisms, and an oxygen-modulated first fluorescent sensor. The body comprises a first layer attached to a second layer, forming at least one isolatable microchamber and at least one primary passageway that provides fluidic communication between ambience and the at least one microchamber. The microchamber has an isolated volume of about 0.5 microliters to about 9.5 microliters. The plurality of test microorganisms and the oxygen-modulated first fluorescent sensor are disposed in the microchamber. A method of using the device to determine the effectiveness of a sterilization process is also provided.
Abstract:
The present invention provides methods to concentrate cells onto microparticles, to concentrate the microparticles, and to detect the cells. The present invention also includes unitary sample preparation and detection devices to be used in accordance with the methods.
Abstract:
Films and articles are described comprising a microstructured surface having an array of peak structures and adjacent valleys. For improved cleanability, the valleys preferably have a maximum width ranging from 10 microns to 250 microns and the peak structures have a side wall angle greater than 10 degrees. The peak structures may comprise two or more facets such as in the case of a linear array of prisms or an array of cube-corners elements. The facets form continuous or semi-continuous surfaces in the same direction. The valleys typically lack intersecting walls. Also described are methods of making and methods of use. The microstructured surface of the article can be prepared by various microreplication techniques such as coating, injection molding, embossing, laser etching, extrusion, casting and curing a polymerizable resin; and bonding microstructured film to a surface or article with an adhesive.
Abstract:
A substantially planar self-folding film assembly to generate a folded three-dimensional assembly. The assembly includes a flexible support substrate, adhesive elements, and folding members. The folding members include a base, a folding region, and a hinge adjacent each folding region attached at the base to the flexible support substrate by at least one of the adhesive elements. An array of polymer actuators is co-extensive, or shaped to be not co-extensive, with each of the flexible folding members. Upon activation by a patterned light to heat conversion layer, each polymer actuator is designed and configured to provide a displacement of the corresponding flexible folding member about each hinge.
Abstract:
A condensation management apparatus comprises a microstructured film arranged to condense water vapor on an underside of a substantially horizontal surface. The film comprises channels disposed at least on a first major surface and configured to support capillary movement of condensate. The channels have a channel axis substantially parallel with a longitudinal axis of the film. A capillary siphon structure of the film comprises a fold in the film, a condensate collection region proximate the fold, and a siphon region between the fold and a condensate release location of the film. At least a portion of a second major surface is attached to the underside of the substantially horizontal surface such that longitudinal openings of the channels of the condensate collection region are oriented towards a direction of gravity and the condensate release location is positioned lower along the direction of gravity than the condensate collection region.