公开(公告)号：US09546184B2

公开(公告)日：2017-01-17

申请号：US14732815

申请日：2015-06-08

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Ryan B. Prince ,  Bryon A. Merrill ,  Philip D. Heppner ,  Tushar A. Kshirsagar ,  Joshua R. Wurst ,  Karl J. Manske ,  Michael J. Rice

IPC: C07D513/04 ,  C07D519/00

CPC classification number: C07D513/04 ,  C07D519/00

Abstract: Thiazoloquinolines and thiazolonaphthyridines with an alkoxy substituent at the 6, 7, 8, or 9-position, pharmaceutical compositions containing the compounds, intermediates, methods of making and methods of use of these compounds as immunomodulators, for inducing cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.

Abstract translation: 含有这些化合物的化合物，中间体，制备方法和这些化合物作为免疫调节剂的使用方法的6,7,8或9位具有烷氧基取代基的噻唑并喹啉和噻唑并萘并用于诱导动物中的细胞因子生物合成 公开了包括病毒和肿瘤疾病在内的疾病的治疗。

公开(公告)号：US10189771B2

公开(公告)日：2019-01-29

申请号：US15550830

申请日：2016-01-28

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Karl E. Benson ,  Ross E. Behling ,  Anish Kurian ,  Ryan B. Prince ,  Joshua R. Wurst ,  Adam R. Wohl ,  Robert J. Webb ,  Sehban Ozair

IPC: C07C69/54 ,  C09J133/08 ,  C08F220/18

Abstract: Protected photocrosslinkers and their use in two-stage photocuring of (meth)acrylate monomers is described.

公开(公告)号：US20160280707A1

公开(公告)日：2016-09-29

申请号：US15181068

申请日：2016-06-13

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Kyle J. Lindstrom ,  Bryon A. Merrill ,  Chad A. Haraldson ,  Michael J. Rice ,  Tushar A. Kshirsagar ,  Philip D. Heppner ,  Joshua R. Wurst ,  Shri Niwas ,  Sarah J. Slania

IPC: C07D471/04 ,  C07D519/00

CPC classification number: C07D471/04 ,  A61K31/4745 ,  C07D413/14 ,  C07D519/00 ,  Y02A50/409 ,  Y02A50/411 ,  Y02A50/463

Abstract: Imidazoquinoline compounds with an alkoxy substituent at the 6, 7, 8, or 9-position, pharmaceutical compositions containing the compounds, intermediates, methods of making, and methods of use of these compounds as immunomodulators, for inducing or inhibiting cytokine biosynthesis in animals and in the treatment of diseases including viral, and neoplastic, are disclosed.

公开(公告)号：US09365567B2

公开(公告)日：2016-06-14

申请号：US14502157

申请日：2014-09-30

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Kyle J. Lindstrom ,  Bryon A. Merrill ,  Chad A. Haraldson ,  Michael J. Rice ,  Tushar A. Kshirsagar ,  Philip D. Heppner ,  Joshua R. Wurst ,  Shri Niwas ,  Sarah J. Slania

IPC: C07D471/04 ,  A61K31/4745 ,  C07D413/14

CPC classification number: C07D471/04 ,  A61K31/4745 ,  C07D413/14 ,  C07D519/00 ,  Y02A50/409 ,  Y02A50/411 ,  Y02A50/463

Abstract: Imidazoquinoline compounds with an alkoxy substituent at the 6, 7, 8, or 9-position, pharmaceutical compositions containing the compounds, intermediates, methods of making, and methods of use of these compounds as immunomodulators, for inducing or inhibiting cytokine biosynthesis in animals and in the treatment of diseases including viral, and neoplastic, are disclosed.

Abstract translation: 含有6,7,8或9位烷氧基取代基的咪唑并喹啉化合物含有化合物，中间体，制备方法，以及这些化合物作为免疫调节剂的用途，用于诱导或抑制动物中的细胞因子生物合成， 在包括病毒和肿瘤的疾病的治疗中。

公开(公告)号：US20150023990A1

公开(公告)日：2015-01-22

申请号：US14502157

申请日：2014-09-30

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Kyle J. Lindstrom ,  Bryon A. Merrill ,  Chad A. Haraldson ,  Michael J. Rice ,  Tushar A. Kshirsagar ,  Philip D. Heppner ,  Joshua R. Wurst ,  Shri Niwas ,  Sarah J. Slania

IPC: C07D471/04

CPC classification number: C07D471/04 ,  A61K31/4745 ,  C07D413/14 ,  C07D519/00 ,  Y02A50/409 ,  Y02A50/411 ,  Y02A50/463

Abstract: Imidazoquinoline compounds with an alkoxy substituent at the 6, 7, 8, or 9-position, pharmaceutical compositions containing the compounds, intermediates, methods of making, and methods of use of these compounds as immunomodulators, for inducing or inhibiting cytokine biosynthesis in animals and in the treatment of diseases including viral, and neoplastic, are disclosed.

Abstract translation: 含有6,7,8或9位烷氧基取代基的咪唑并喹啉化合物含有化合物，中间体，制备方法，以及这些化合物作为免疫调节剂的用途，用于诱导或抑制动物中的细胞因子生物合成， 在包括病毒和肿瘤的疾病的治疗中。

公开(公告)号：US20190092979A1

公开(公告)日：2019-03-28

申请号：US16080320

申请日：2017-02-03

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Robert B. Rosner ,  Joshua R. Wurst ,  Robert J. Shimanek, III ,  Rhesa M. Browning ,  Ann R. Fornof ,  Dong-Wei Zhu ,  Adam R. Wohl

IPC: C09J7/38 ,  C08F220/14 ,  C08F220/12 ,  C09J7/25 ,  C09J7/21

Abstract: The present disclosure provides an oil-resistant adhesive comprising a crosslinked copolymer of (meth)acrylic ester monomers, methyl (meth)acrylate monomers, vinyl ester monomers, and a functional monomer selected from one of (meth)acrylic acid, a (meth)acrylamide or a hydroxyalkyl (meth)acrylate monomers.

公开(公告)号：US20160369069A1

公开(公告)日：2016-12-22

申请号：US15251704

申请日：2016-08-30

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Anthony P. Manzara ,  Michael D. Crandall ,  Joshua R. Wurst

IPC: C08J3/24 ,  C08G63/91 ,  C08G18/83 ,  C08F220/12

CPC classification number: C08J3/244 ,  C08F220/12 ,  C08G18/6229 ,  C08G18/6254 ,  C08G18/8064 ,  C08G18/807 ,  C08G18/83 ,  C08G18/833 ,  C08G63/91 ,  C08G63/912 ,  C08G2170/40 ,  C08J3/243 ,  C08J3/246 ,  C08J2333/06 ,  C08J2367/02 ,  C08J2375/04 ,  C09J175/04

Abstract: Described herein is a mixture comprising: (a) a non-self-crosslinking polymer; and (b) a modifying compound comprising: (i) a first functional group capable of reacting with the reaction sites of the non-self-crosslinking polymer; and (ii) a second functional group capable of crosslinking with a curing agent, wherein the first functional group is different than the second functional group. Also, described are curable polymeric compositions, and methods of making cured polymeric compositions.

Abstract translation: 本文描述的是一种混合物，其包含：（a）非自交联聚合物; 和（b）改性化合物，其包含：（i）能够与非自交联聚合物的反应位点反应的第一官能团; 和（ii）能够与固化剂交联的第二官能团，其中第一官能团不同于第二官能团。 还描述了可固化的聚合物组合物和制备固化的聚合物组合物的方法。

公开(公告)号：US20140187722A1

公开(公告)日：2014-07-03

申请号：US14197731

申请日：2014-03-05

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Anthony P. Manzara ,  Michael D. Crandall ,  Joshua R. Wurst

IPC: C08J3/24 ,  C08G63/91 ,  C08G18/83 ,  C08F220/12

CPC classification number: C08J3/244 ,  C08F220/12 ,  C08G18/6229 ,  C08G18/6254 ,  C08G18/8064 ,  C08G18/807 ,  C08G18/83 ,  C08G18/833 ,  C08G63/91 ,  C08G63/912 ,  C08G2170/40 ,  C08J3/243 ,  C08J3/246 ,  C08J2333/06 ,  C08J2367/02 ,  C08J2375/04 ,  C09J175/04

Abstract: Described herein is a composition comprising at least one of: X—R—(Z)n wherein X is selected from: an aziridine amide, an aziridine urea, an isocyanate, an alcohol, an amine, an epoxy, or a sulfhydryl, R is a multifunctional organic group, and Z is selected from —N3 or —C≡C—R′, wherein R′ is a hydrogen or a monofunctional organic group and n is from one to about 10. Also, described are mixtures, curable polymeric compositions, and methods of making cured polymeric compositions.

Abstract translation: 本文描述的是包含以下至少一种的组合物：X-R-（Z）n，其中X选自：氮丙啶酰胺，氮丙啶脲，异氰酸酯，醇，胺，环氧基或巯基，R 是多官能有机基团，Z选自-N 3或-C≡C-R'，其中R'为氢或单官能有机基团，n为1至约10.另外，描述了可固化聚合物 组合物和制备固化的聚合物组合物的方法。

公开(公告)号：US20220177471A1

公开(公告)日：2022-06-09

申请号：US17594415

申请日：2020-05-27

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： George W. Griesgraber ,  Michael J. Rice ,  Hannah C. Cohen ,  Devon M. Hunerdosse ,  Adam D. Miller ,  Joshua R. Wurst

IPC: C07D471/04

Abstract: Imidazo[4,5-c]quinoline compounds having a substituent that is attached at the N-1 position by a branched group, single enantiomers of the compounds, pharmaceutical compositions containing the compounds, and methods of making the compounds are disclosed. Methods of use of the compounds as immune response modifiers, for inducing (or inhibiting) cytokine biosynthesis in humans and animals, and in the treatment of diseases including infectious and neoplastic diseases are also disclosed.

公开(公告)号：US10947423B2

公开(公告)日：2021-03-16

申请号：US16080320

申请日：2017-02-03

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Robert B. Rosner ,  Joshua R. Wurst ,  Robert J. Shimanek, III ,  Rhesa M. Browning ,  Ann R. Fornof ,  Dong-Wei Zhu ,  Adam R. Wohl

IPC: C09J7/38 ,  C08F220/14 ,  C08F220/12 ,  C09J7/25 ,  C09J7/21 ,  C09J133/26 ,  C09J133/02 ,  C09J133/06 ,  C08F220/20 ,  C08F218/08 ,  C08F220/18 ,  C08F220/28

Abstract: The present disclosure provides an oil-resistant adhesive comprising a crosslinked copolymer of (meth)acrylic ester monomers, methyl (meth)acrylate monomers, vinyl ester monomers, and a functional monomer selected from one of (meth)acrylic acid, a (meth)acrylamide or a hydroxyalkyl (meth)acrylate monomers.