公开(公告)号：PT846114E

公开(公告)日：2002-05-31

申请号：PT96914786

申请日：1996-05-28

Applicant: ABBOTT LAB

Inventor： LIN NAN-HORNG ,  RYTHER KEITH B ,  HE YUN ,  HOLLADAY MARY W

IPC: A61K31/00 ,  A61K31/44 ,  A61K31/4427 ,  A61K31/4439 ,  A61P25/00 ,  A61P25/04 ,  C07D401/12 ,  C07D403/12 ,  C07D417/12

Abstract: Novel 3-pyridyloxymethyl heterocyclic ether compounds having formula (I), wherein * is a chiral center and n, X, R , R , A andB are specifically defined, which are useful in controlling chemical synaptic transmission; therapeutically-effective pharmaceutical compositions therof; and use of said compositions to selectively control synaptic transmission in mammals.