公开(公告)号：JPH02184633A

公开(公告)日：1990-07-19

申请号：JP30305589

申请日：1989-11-21

Applicant: ABBOTT LAB

Inventor： HAWAADO ROORENSU SHIYOU ,  JIEFURII ASUKANAJI ,  UIRIAMU DEII REZEMU

IPC: A61K38/00 ,  A61K9/10 ,  A61K9/107 ,  A61K31/20 ,  A61K31/23 ,  A61K31/66 ,  A61K31/685 ,  A61K35/54 ,  A61K36/48 ,  A61P31/12 ,  A61P31/18

Abstract: PURPOSE: To prepare a therapeutic agent for AIDS comprising an emulsion composition for parenteral administration containing specific amounts of soybean oil and an egg phosphatide. CONSTITUTION: This emulsion composition for parenteral administration comprises about 2-7wt.%, preferably about 2wt.% soybean oil and about 1-2wt.%, preferably about 1.2wt.% egg phosphatide. The composition has a higher ratio of the egg phosphatide/triglyceride than that of a commercially available lipid emulsion. Thereby, a sufficient level of the egg phosphatide can be provided to promote the mobilization of tissue cholesterol without causing the fat overload. The daily dose of the emulsion is within the range of 5-30mL/kg.