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公开(公告)号：BG103737A
公开(公告)日：2000-06-30
申请号：BG10373799
申请日：1999-09-16
Applicant: ABBOTT LAB
Inventor： WANG WEI-BO , KERDESKY FRANCIS A , HSIAO CHI-NUNG W , LI QUN , CHU DANIEL T
IPC: C07D455/02
Abstract: The invention relates to a method for the preparation of compounds with the formula where R1, R2, R3, R4 & R5 have the meanings listed in the description, from enamine by extending the chain and closing of a ring followed by additional production of derivatives, treatment with 3-alkoxyacryloyl compound, yet another closing of a ring and conversion of the hydroxy group into a splitting one. 10 claims
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