公开(公告)号：US3856958A

公开(公告)日：1974-12-24

申请号：US42539473

申请日：1973-12-17

Applicant: ABBOTT LAB

Inventor： LEE C

IPC: C07D263/48 ,  A61K27/00

CPC classification number: C07D263/48

Abstract: 1-(5-Phenyl-4-oxo-2-oxazolin-2-yl)-4-cinnamoylpiperazines represented by the formula WHEREIN R is hydrogen or loweralkyl; R'' is hydrogen or loweralkyl; and X, Y and Z each are hydrogen, halogen or loweralkyl. The compounds exhibit anti-depressant activity.

公开(公告)号：US3816426A

公开(公告)日：1974-06-11

申请号：US26896672

申请日：1972-07-05

Applicant: ABBOTT LAB

Inventor： LEE C

IPC: C07D413/04 ,  C07D51/70

CPC classification number: C07D413/04

Abstract: COVERS 1-(5-PHENYL-4-OXO-2-OXAZOLIN-2-YL)PIPERAZINES WHICH ARE USEFUL AS ANTI-DEPRESSANTS.

公开(公告)号：ZA7403647B

公开(公告)日：1975-05-28

申请号：ZA7403647

申请日：1974-06-07

Applicant: ABBOTT LAB

Inventor： LEE C

IPC: C07D20060101 ,  C07D

公开(公告)号：SE351217B

公开(公告)日：1972-11-20

申请号：SE1473270

申请日：1970-11-02

Applicant: ABBOTT LAB

Inventor： LEE C ,  HORROM B

IPC: C07D263/48 ,  C07D85/40

公开(公告)号：ZA7006797B

公开(公告)日：1971-07-28

申请号：ZA7006797

申请日：1970-10-06

Applicant: ABBOTT LAB

Inventor： LEE C ,  HORROM B

IPC: C07D263/48 ,  A61K ,  C07C

CPC classification number: C07D263/48

公开(公告)号：BE885586A

公开(公告)日：1981-04-08

申请号：BE202374

申请日：1980-10-08

Applicant: ABBOTT LAB

Inventor： OURS C ,  LEE C

IPC: A61K31/135 ,  A61K31/16 ,  A61K31/165 ,  A61P7/10 ,  C07C59/90 ,  C07C67/00 ,  C07C213/00 ,  C07C225/16 ,  C07C231/00 ,  C07C235/20 ,  C07C313/00 ,  C07C323/32 ,  C07D295/112 ,  C07C ,  A61K

公开(公告)号：ZA7606571B

公开(公告)日：1977-10-26

申请号：ZA7606571

申请日：1976-11-02

Applicant: ABBOTT LAB

Inventor： LEE C ,  PLOTNIKOFF N ,  ZAUGG H ,  MICHAELS R

IPC: C07C69/035 ,  A61K31/047 ,  A61K31/05 ,  A61K31/44 ,  A61K31/4418 ,  A61P25/18 ,  C07C27/00 ,  C07C39/12 ,  C07C39/15 ,  C07C39/21 ,  C07C45/66 ,  C07C49/796 ,  C07C49/83 ,  C07C67/00 ,  C07D213/30 ,  C07D491/04 ,  C07D491/052 ,  C07C

CPC classification number: C07D213/30 ,  C07C39/12 ,  C07C39/15 ,  C07C45/66 ,  C07C49/796 ,  C07C49/83 ,  C07D491/04

公开(公告)号：ZA706797B

公开(公告)日：1971-07-28

申请号：ZA706797

申请日：1970-10-06

Applicant: ABBOTT LAB

Inventor： LEE C ,  HORROM B

IPC: C07D263/48 ,  A61K ,  C07C

公开(公告)号：PH12341A

公开(公告)日：1979-01-16

申请号：PH19113

申请日：1976-11-10

Applicant: ABBOTT LAB

Inventor： LEE C ,  ZAUGG H ,  PLOTHIKOFF N ,  MICHAELS R

IPC: C07C69/035 ,  A61K31/047 ,  A61K31/05 ,  A61K31/44 ,  A61K31/4418 ,  A61P25/18 ,  C07C27/00 ,  C07C39/12 ,  C07C39/15 ,  C07C39/21 ,  C07C45/66 ,  C07C49/796 ,  C07C49/83 ,  C07C67/00 ,  C07D213/30 ,  C07D491/04 ,  C07D491/052 ,  C07C39/02

公开(公告)号：ZA743647B

公开(公告)日：1975-05-28

申请号：ZA743647

申请日：1974-06-07

Applicant: ABBOTT LAB

Inventor： LEE C

IPC: C07D20060101 ,  C07D

Abstract: 5H-[1]Benzopyrano[3,4-d]pyridines represented by the formula WHEREIN EACH R1 is loweralkyl, R2 is alkyl, cycloalkyl or WHEREIN Y is a straight or branched chain alkylene group having from 1 to 10 carbon atoms and each R4, R5 and R6 are the same or different members of the group consisting of hydrogen, halo, trifluoromethyl or loweralkyl; and R3 is hydroxy, acyloxy or X is a straight or branched chain alkylene group having from 1 to 8 carbon atoms, and wherein R7 and R8 are the same or different members of the group consisting of hydrogen or loweralkyl, or WHEREIN X is a straight or branched chain alkylene group having from 1 to 8 carbon atoms, a is an integer from 1 to 4, b is an integer from 1 to 4, Z is CH2, O, S or NR10 with R10 being hydrogen or loweralkyl, with the limitation that when Z is O or S, the sum of a and b is 3 or 4; and when Z is NR10, the sum of a and b is 3-5; R9 is hydrogen or loweralkyl, and the pharmaceutically acceptable salts thereof.