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公开(公告)号：WO2010030359A8
公开(公告)日：2011-05-12
申请号：PCT/US2009005082
申请日：2009-09-10
Applicant: ENANTA PHARM INC , ABBOTT LAB , KU YIYIN , MCDANIEL KEITH F , CHEN HUI-JU , SHANLEY JASON P , KEMPF DALE J , GRAMPOVNIK DAVID J , SUN YING , LIU DONG , GAI YONGHUA , OR YAT SUN , WAGAW SABLE H , ENGSTROM KEN , GRIEME TIM , SHEIKH AHMAD , MEI JIANZHANG
Inventor： KU YIYIN , MCDANIEL KEITH F , CHEN HUI-JU , SHANLEY JASON P , KEMPF DALE J , GRAMPOVNIK DAVID J , SUN YING , LIU DONG , GAI YONGHUA , OR YAT SUN , WAGAW SABLE H , ENGSTROM KEN , GRIEME TIM , SHEIKH AHMAD , MEI JIANZHANG
CPC classification number: C07K1/113 , C07D487/04
Abstract: The present invention relates to novel macrocyclic compounds and methods of use thereof. The present invention further relates to pharmaceutical compositions comprising the compounds of the present invention, or pharmaceutically acceptable salts, esters, or prodrugs thereof, in combination with a pharmaceutically acceptable carrier or excipient.
Abstract translation: 本发明涉及新的大环化合物及其使用方法。 本发明还涉及包含本发明化合物或其药学上可接受的盐，酯或前药与药学上可接受的载体或赋形剂组合的药物组合物。
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公开(公告)号：WO2010030359A3
公开(公告)日：2010-05-27
申请号：PCT/US2009005082
申请日：2009-09-10
Applicant: ENANTA PHARJMACEUTICALS INC , ABBOTT LAB , KU YIYIN , MCDANIEL KEITH F , CHEN HUI-JU , SHANLEY JASON P , KEMPF DALE J , GRAMPOVNIK DAVID J , SUN YING , LIU DONG , GAI YONGHUA , OR YAT SUN , WAGAW SABLE H , ENGSTROM KEN , GRIEME TIM , SHEIKH AHMAD , MEI JIANZHANG
Inventor： KU YIYIN , MCDANIEL KEITH F , CHEN HUI-JU , SHANLEY JASON P , KEMPF DALE J , GRAMPOVNIK DAVID J , SUN YING , LIU DONG , GAI YONGHUA , OR YAT SUN , WAGAW SABLE H , ENGSTROM KEN , GRIEME TIM , SHEIKH AHMAD , MEI JIANZHANG
CPC classification number: C07K1/113 , C07D487/04
Abstract: The present invention relates to novel macrocyclic compounds and methods of use thereof. The present invention further relates to pharmaceutical compositions comprising the compounds of the present invention, or pharmaceutically acceptable salts, esters, or prodrugs thereof, in combination with a pharmaceutically acceptable carrier or excipient.
Abstract translation: 本发明涉及新的大环化合物及其使用方法。 本发明还涉及包含本发明化合物或其药学上可接受的盐，酯或前药与药学上可接受的载体或赋形剂组合的药物组合物。
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公开(公告)号：EP2340029A4
公开(公告)日：2012-06-13
申请号：EP09813360
申请日：2009-09-10
Applicant: ENANTA PHARM INC , ABBOTT LAB
Inventor： KU YIYIN , MCDANIEL KEITH F , CHEN HUI-JU , SHANLEY JASON P , KEMPF DALE J , GRAMPOVNIK DAVID J , SUN YING , LIU DONG , GAI YONGHUA , OR YAT SUN , WAGAW SABLE H , ENGSTROM KEN , GRIEME TIM , SHEIKH AHMAD , MEI JIANZHANG
IPC: A61K38/00 , A61K38/12 , C07D487/04
CPC classification number: C07K1/113 , C07D487/04
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公开(公告)号：AU2013205039A1
公开(公告)日：2013-05-16
申请号：AU2013205039
申请日：2013-04-13
Applicant: ABBOTT LAB , ENANTA PHARM INC
Inventor： KU YIYIN , MCDANIEL KEITH F , CHEN HUI-JU , SHANLEY JASON P , KEMPF DALE J , GRAMPOVNIK DAVID J , SUN YING , LIU DONG , YONGHUA GAI , OR YAT SUN , WAGAW SABLE H , ENGSTROM KEN , GRIEME TIM , SHEIKH AHMAD , MEI JIANZHANG
Abstract: MACROCYCLIC HEPATITIS C SERINE PROTEASE Abstract The present invention relates to novel macrocyclic compounds and methods of use thereof. The present invention further relates to pharmaceutical compositions comprising the compounds of the present invention, or pharmaceutical acceptable salts, esters, or prodrugs thereof, in combination with a pharmaceutical carrier or excipient.
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公开(公告)号：CA2727932A1
公开(公告)日：2009-12-23
申请号：CA2727932
申请日：2009-06-18
Applicant: ABBOTT LAB
Inventor： FRANCZYK THADDEUS S II , HILL DAVID R , HAIGHT ANTHONY R , MCLAUGLIN MAUREEN ANN , SHEKHAR SHASHANK , YU SU , MEI JIANZHANG , WANG LEI
IPC: C07D295/155
Abstract: A process for the preparation of the apoptosis promoter N-(4-(4-((2-(4-chlorophenyl)-5,5- dimethyl- 1 -cyclohex- 1 -en- 1 -yl)methyl)piperazin- 1 -yl)benzoyl)-4-((( 1 R)-3-(morpholin-4-yl)- 1-((phenylsulfanyl) methyl)propyl)amino)-3-(trifluoromethyl)sulfonyl)benzenesulfonamide (ABT-263). Formula (I).
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Patent Agency Ranking
公开(公告)号：CY1114242T1
公开(公告)日：2016-08-31
申请号：CY131100489
申请日：2013-06-18
Applicant: ABBOTT LAB
Inventor： FRANCZYK THADDEUS S II , HILL DAVID R , HAIGHT ANTHONY R , MCLAUGLIN MAUREEN ANN , SHEKHAR SHASHANK , YU SU , MEI JIANZHANG , WANG LEI
IPC: C07D295/13 , C07D295/155
Abstract: ΜιαδιεργασίαγιατηνπαρασκευήτουυποκινητήαπόπτωσηςΝ-(4-(4-((2-(4-χλωροφαινυλ)-5,5-διμεθυλ-1-κυκλοεξ-1-εν-υλ)μεθυλ)πιπεραζιν-1-υλ)βενζοϋλ)-4-(((1R)-3 -(μορφολιν-4-υλ)-1-((φαινυλοσουλφανυλ)-μεθυλ)προπυλ)αμινο)-3-(τριφθορομεθυλ)σουλφονυλ)βενζολοσουλφοναμιδίου (ΑΒΤ-263). Τύπος (I).
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公开(公告)号：PT2307393E
公开(公告)日：2013-06-27
申请号：PT09767695
申请日：2009-06-18
Applicant: ABBOTT LAB
Inventor： HAIGHT ANTHONY R , HILL DAVID R , FRANCZYK THADDEUS S II , MCLAUGLIN MAUREEN ANN , SHEKHAR SHASHANK , YU SU , MEI JIANZHANG , WANG LEI
IPC: C07D295/13 , C07D295/155
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公开(公告)号：BRPI0918724A2
公开(公告)日：2013-06-18
申请号：BRPI0918724
申请日：2009-09-10
Applicant: ENANTA PHARM INC , ABBOTT LAB
Inventor： KU YIYIN , MCDANIEL KEITH F , CHEN HUI-JU , SHANLEY JASON P , KEMPF DALE J , GRAMPOVNIK DAVID J , SUN YING , LIU DONG , GAI YONGHUA , OR YAT SUN , WAGAN SABLE H , ENGSTROM KEN , GRIEME TIM , SHEIKH AHMAD , MEI JIANZHANG
Abstract: The present invention relates to novel macrocyclic compounds and methods of use thereof. The present invention further relates to pharmaceutical compositions comprising the compounds of the present invention, or pharmaceutically acceptable salts, esters, or prodrugs thereof, in combination with a pharmaceutically acceptable carrier or excipient.
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公开(公告)号：AU2013205040A1
公开(公告)日：2013-05-16
申请号：AU2013205040
申请日：2013-04-13
Applicant: ABBOTT LAB , ENANTA PHARM INC
Inventor： KU YIYIN , MCDANIEL KEITH F , CHEN HUI-JU , SHANLEY JASON P , KEMPF DALE J , GRAMPOVNIK DAVID J , SUN YING , LIU DONG , YONGHUA GAI , OR YAT SUN , WAGAW SABLE H , ENGSTROM KEN , GRIEME TIM , SHEIKH AHMAD , MEI JIANZHANG
Abstract: MACROCYCLIC HEPATITIS C SERINE PROTEASE Abstract The present invention relates to novel macrocyclic compounds and methods of use thereof. The present invention further relates to pharmaceutical compositions comprising the compounds of the present invention, or pharmaceutical acceptable salts, esters, or prodrugs thereof, in combination with a pharmaceutical carrier or excipient.
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公开(公告)号：SG179414A1
公开(公告)日：2012-04-27
申请号：SG2012014080
申请日：2009-09-10
Applicant: ABBOTT LAB , ENANTA PHARM INC
Inventor： KU YIYIN , MCDANIEL KEITH F , CHEN HUI-JU , SHANLEY JASON P , KEMPF DALE J , GRAMPOVNIK DAVID J , SUN YING , LIU DONG , GAI YONGHUA , OR YAT SUN , WAGAW SABLE H , ENGSTROM KEN , GRIEME TIM , SHEIKH AHMAD , MEI JIANZHANG
Abstract: The present invention relates to novel macrocyclic compounds and methods of use thereof. The present invention further relates to pharmaceutical compositions comprising the compounds of the present invention, or pharmaceutically acceptable salts, esters, or prodrugs thereof, in combination with a pharmaceutically acceptable carrier or excipient.
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