公开(公告)号：SE7906433L

公开(公告)日：1980-11-08

申请号：SE7906433

申请日：1979-07-27

Applicant: ABBOTT LAB

Inventor： WINN M ,  NORDEEN C W

IPC: C07D231/38 ,  C07D231/40 ,  C07D403/12

公开(公告)号：BE768305A

公开(公告)日：1971-12-09

申请号：BE768305

申请日：1971-06-09

Applicant: ABBOTT LAB

Inventor： STEIN R G ,  NORDEEN C W

IPC: C07D513/04 ,  C07D

Abstract: 1321360 Process for preparing 2,3-dihydro-1H- pyrido[2,3-b][1,4]thiazin-2-ones ABBOTT LABORATORIES 19 April 1971 [20 Jan 1971] 25672/71 Heading C2C A process for preparing compounds of the Formula I wherein each of Rand X is hydrogen or methyl, comprises reacting a 2-mercapto-3-nitropyridine of the formula with a haloacetic acid or ester Y-CHRCOOR 2 wherein Y is bromo, chloro, fluoro, or iodo, R 2 is hydrogen, methyl and ethyl in a suitable solvent to yield a 3-nitro-pyridinyl-2-thioacetic acid or ester III and hydrogenating the compound III. Pharmaceutical compositions of the compounds I show anti-inflammatory activity.