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公开(公告)号：EP0480918A4
公开(公告)日：1991-06-04
申请号：EP89902991
申请日：1989-02-09
Applicant: ABBOTT LAB
Inventor： HAVIV FORTUNA , GREER JONATHAN , PALABRICA CHRISTOPHER A
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2.发明专利
公开(公告)号：HU904911D0
公开(公告)日：1991-01-28
申请号：HU491190
申请日：1990-08-06
Applicant: ABBOTT LAB
Inventor： HAVIV FORTUNA , GREER JONATHAN , PALABRICA CHRISTOPHER A , FITZPATRICK TIMOTHY D
Abstract: The present invention relates to novel LHRH analogs. The LHRH analogs include "pseudo" hexapeptide, heptapeptide, octapeptide and nonapeptide analogs of LHRH, wherein all or some of the amino acids 1, 2 and 3 have been eliminated and the remaining (2-9), (2-10), (3-9), (3-10), (4-9) or (4-10) peptide is linked to various carboxylic acids which take the place of amino acids 1, 2 or 3 in LHRH.
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公开(公告)号：CA2022437A1
公开(公告)日：1991-02-08
申请号：CA2022437
申请日：1990-08-01
Applicant: ABBOTT LAB
Inventor： HAVIV FORTUNA , GREER JONATHAN , PALABRICA CHRISTOPHER A , FITZPATRICK TIMOTHY D
Abstract: The present invention relates to novel LHRH analogs. The LHRH analogs include "pseudo" hexapeptide, heptapeptide, octapeptide and nonapeptide analogs of LHRH, wherein all or some of the amino acids 1, 2 and 3 have been eliminated and the remaining (2-9), (2-10), (3-9), (3-10), (4-9) or (4-10) peptide is linked to various carboxylic acids which take the place of amino acids 1, 2 or 3 in LHRH.
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公开(公告)号：NO903454D0
公开(公告)日：1990-08-06
申请号：NO903454
申请日：1990-08-06
Applicant: ABBOTT LAB
Inventor： HAVIV FORTUNA , GREER JONATHAN , PALABRICA CHRISTOPHER A , FITZPATRICK TIMOTHY D
Abstract: The present invention relates to novel LHRH analogs. The LHRH analogs include "pseudo" hexapeptide, heptapeptide, octapeptide and nonapeptide analogs of LHRH, wherein all or some of the amino acids 1, 2 and 3 have been eliminated and the remaining (2-9), (2-10), (3-9), (3-10), (4-9) or (4-10) peptide is linked to various carboxylic acids which take the place of amino acids 1, 2 or 3 in LHRH.
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公开(公告)号：NO903454A
公开(公告)日：1991-02-08
申请号：NO903454
申请日：1990-08-06
Applicant: ABBOTT LAB
Inventor： HAVIV FORTUNA , GREER JONATHAN , PALABRICA CHRISTOPHER A , FITZPATRICK TIMOTHY D
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Patent Agency Ranking
公开(公告)号：NO903454L
公开(公告)日：1991-02-08
申请号：NO903454
申请日：1990-08-06
Applicant: ABBOTT LAB
Inventor： HAVIV FORTUNA , GREER JONATHAN , PALABRICA CHRISTOPHER A , FITZPATRICK TIMOTHY D
Abstract: The present invention relates to novel LHRH analogs. The LHRH analogs include "pseudo" hexapeptide, heptapeptide, octapeptide and nonapeptide analogs of LHRH, wherein all or some of the amino acids 1, 2 and 3 have been eliminated and the remaining (2-9), (2-10), (3-9), (3-10), (4-9) or (4-10) peptide is linked to various carboxylic acids which take the place of amino acids 1, 2 or 3 in LHRH.
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公开(公告)号：CA2022437C
公开(公告)日：2002-10-22
申请号：CA2022437
申请日：1990-08-01
Applicant: ABBOTT LAB
Inventor： HAVIV FORTUNA , GREER JONATHAN , PALABRICA CHRISTOPHER A , FITZPATRICK TIMOTHY D
Abstract: The present invention relates to novel LHRH analogs. The LHRH analogs include "pseudo" hexapeptide, heptapeptide, octapeptide and nonapeptide analogs of LHRH, wherein all or some of the amino acids 1, 2 and 3 have been eliminated and the remaining (2-9), (2-10), (3-9), (3-10), (4-9) or (4-10) peptide is linked to various carboxylic acids which take the place of amino acids 1, 2 or 3 in LHRH.
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8.发明专利
公开(公告)号：HUT55414A
公开(公告)日：1991-05-28
申请号：HU491190
申请日：1990-08-06
Applicant: ABBOTT LAB
Inventor： HAVIV FORTUNA , GREER JONATHAN , PALABRICA CHRISTOPHER A , FITZPATRICK TIMOTHY D
Abstract: The present invention relates to novel LHRH analogs. The LHRH analogs include "pseudo" hexapeptide, heptapeptide, octapeptide and nonapeptide analogs of LHRH, wherein all or some of the amino acids 1, 2 and 3 have been eliminated and the remaining (2-9), (2-10), (3-9), (3-10), (4-9) or (4-10) peptide is linked to various carboxylic acids which take the place of amino acids 1, 2 or 3 in LHRH.
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公开(公告)号：PL286389A1
公开(公告)日：1991-05-06
申请号：PL28638990
申请日：1990-08-07
Applicant: ABBOTT LAB
Inventor： HAVIV FORTUNA , GREER JONATHAN , PALABRICA CHRISTOPHER A , FITZPATRICK TIMOTHY D
Abstract: The present invention relates to novel LHRH analogs. The LHRH analogs include "pseudo" hexapeptide, heptapeptide, octapeptide and nonapeptide analogs of LHRH, wherein all or some of the amino acids 1, 2 and 3 have been eliminated and the remaining (2-9), (2-10), (3-9), (3-10), (4-9) or (4-10) peptide is linked to various carboxylic acids which take the place of amino acids 1, 2 or 3 in LHRH.
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公开(公告)号：PT94923A
公开(公告)日：1991-04-18
申请号：PT9492390
申请日：1990-08-06
Applicant: ABBOTT LAB
Inventor： HAVIV FORTUNA , GREER JONATHAN , PALABRICA CHRISTOPHER A , FITZPATRICK TIMOTHY D
Abstract: The present invention relates to the process for preparation of new LHRH analogues. The LHRH analogues include "pseudo" hexapeptide, heptapeptide, octapeptide and nonapeptide LHRH analogues, in which all or some of the amino acids 1, 2 and 3 have been eliminated and the remaining peptide (2-9), (2-10), (3-9), (3-10), (4-9) or (4-10) is bound to various carboxylic acids which take the place of amino acids 1, 2 or 3 in LHRH. The process comprises the coupling of adequately protected amino acids, or of analogues of these amino acids, followed by removal of the protecting groups. The invention also relates to the process for preparation of pharmaceutical compositions.
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