公开(公告)号：WO9945105A2

公开(公告)日：1999-09-10

申请号：PCT/US9904992

申请日：1999-03-05

Applicant: ABBOTT LAB

Inventor： WANG JIEYI ,  NIENABER VICKI L ,  HENKIN JACK ,  SMITH RICHARD A ,  WALTER KARL A ,  SEVERIN JEAN M ,  EDALJI ROHINTON ,  JOHNSON ROBERT W JR ,  HOLZMAN THOMAS

IPC: C12N15/00 ,  C12N1/15 ,  C12N1/19 ,  C12N1/21 ,  C12N5/10 ,  C12N9/50 ,  C12N9/72 ,  C12N9/00

CPC classification number: C12N9/6462 ,  C12Y304/21073

Abstract: The present disclosure describes a biologically active modified urokinase and high resolution crystalline forms of modified urokinase. Polynucleotides which encode modified urokinase and methods for making modified urokinase are also disclosed.

Abstract translation: 本公开描述了生物活性修饰尿激酶和修饰尿激酶的高分辨率晶体形式。 还公开了编码改变的尿激酶的多核苷酸和制备修饰尿激酶的方法。

公开(公告)号：CA2322622A1

公开(公告)日：1999-09-10

申请号：CA2322622

申请日：1999-03-05

Applicant: ABBOTT LAB

Inventor： WALTER KARL A ,  SMITH RICHARD A ,  EDALJI ROHINTON ,  SEVERIN JEAN M ,  WANG JIEYI ,  JOHNSON ROBERT W JR ,  NIENABER VICKI L ,  HENKIN JACK ,  HOLZMAN THOMAS

IPC: C12N15/00 ,  C12N1/15 ,  C12N1/19 ,  C12N1/21 ,  C12N5/10 ,  C12N9/50 ,  C12N9/72 ,  C12N15/58 ,  C12N15/86 ,  C12P21/02

Abstract: The present disclosure describes a biologically active modified urokinase and high resolution crystalline forms of modified urokinase. Polynucleotides which encode modified urokinase and methods for making modified urokinase are also disclosed.