公开(公告)号：EP0710295A4

公开(公告)日：1998-05-06

申请号：EP94923296

申请日：1994-06-30

Applicant: ABBOTT LAB

Inventor： LEE HELEN H ,  SWANSON PRISCILLA A ,  IDLER KENNETH B ,  ROSENBLATT JOSEPH D ,  CHEN IRVIN S Y ,  GOLDE DAVID W ,  ROBERTSON EUGENE ,  STEPHENS JOHN E ,  CHAN EMERSON W ,  BUYTENDORP MARK H ,  JOHNSON JOAN E ,  MOTLEY CHERYL T ,  EDWARDS MICHELLE ,  TATE CYNTHIA ,  PETERSON BRYAN ,  GUIDINGER PEGGY

IPC: G01N33/53 ,  A61K38/00 ,  C07K14/15 ,  C07K16/10 ,  C12N5/10 ,  C12N7/00 ,  C12N15/09 ,  C12P21/02 ,  C12Q1/70 ,  G01N33/543 ,  G01N33/569 ,  C07K2/00 ,  C07K14/00 ,  C07K17/00 ,  C07K17/08 ,  C07K17/12 ,  C12N7/02

CPC classification number: C07K14/005 ,  A61K38/00 ,  C12N2740/14022 ,  G01N33/56988

公开(公告)号：AU7816591A

公开(公告)日：1991-10-10

申请号：AU7816591

申请日：1991-06-04

Applicant: ABBOTT LAB

Inventor： CHAN EMERSON W ,  SCHULZE WERNER ,  ROBEY WILLIAM GERARD ,  STOJAK JOSEPH J II ,  VALLARI DAVID S ,  BRAUN BRIAN P ,  DALUGA CYNTHIA K ,  KAPSALIS ANDREAS A ,  KNIGGE KEVIN M ,  STEPHENS JOHN E

IPC: G01N33/543 ,  G01N33/569 ,  G01N33/571

Abstract: An immunoassay which is capable of simultaneously detecting any desired number of antigens of one infectious agent, or combinations of antigens of several infectious agents, or any desired number of immunoglobulins of one infectious agent, or combinations of immunoglobulins of several infectious agents on a single solid support. A test sample is contacted with a solid support on which one or more antigens are immobilized as discrete test sites. Antigen-antibody complexes are formed and detected on the solid support.

公开(公告)号：CA2166291C

公开(公告)日：2008-05-13

申请号：CA2166291

申请日：1994-06-30

Applicant: ABBOTT LAB ,  UNIV CALIFORNIA

Inventor： GUIDINGER PEGGY ,  LEE HELEN H ,  SWANSON PRISCILLA A ,  IDLER KENNETH B ,  ROSENBLATT JOSEPH D ,  CHEN IRVIN S Y ,  GOLDE DAVID W ,  ROBERTSON EUGENE ,  STEPHENS JOHN E ,  CHAN EMERSON W ,  BUYTENDORP MARK H ,  JOHNSON JOAN E ,  MOTLEY CHERYL T ,  EDWARDS MICHELLE ,  TATE CYNTHIA ,  PETERSON BRYAN

IPC: C12N15/48 ,  G01N33/53 ,  A61K38/00 ,  C07K14/15 ,  C07K16/10 ,  C07K19/00 ,  C12N5/10 ,  C12N7/00 ,  C12N9/12 ,  C12N15/09 ,  C12P21/02 ,  C12Q1/70 ,  G01N33/543 ,  G01N33/569 ,  G01N33/577

Abstract: Compositions including lysates, DNA and amino acid sequences derived from HT LV- II NRA are provided. Assays for detecting HTLV infection that employ the disclosed HTLV-II NRA compositions are also provided. Kits for performing HTLV assays are further provided.

公开(公告)号：AU7868998A

公开(公告)日：1998-10-22

申请号：AU7868998

申请日：1998-07-30

Applicant: ABBOTT LAB

Inventor： LEE HELEN H ,  SWANSON PRISCILLA A ,  IDLER KENNETH B ,  ROSENBLATT JOSEPH D ,  CHEN IRVIN S Y ,  GOLDE DAVID W ,  ROBERTSON EUGENE ,  STEPHENS JOHN E ,  CHAN EMERSON W ,  BUYTENDORP MARK H ,  JOHNSON JOAN E ,  MOTLEY CHERYL T ,  EDWARDS MICHELLE ,  TATE CYNTHIA ,  PETERSON BRYAN ,  GUIDINGER PEGGY

IPC: C12N15/49 ,  G01N33/569

公开(公告)号：AU8174694A

公开(公告)日：1995-03-16

申请号：AU8174694

申请日：1994-12-23

Applicant: ABBOTT LAB

Inventor： CHAN EMERSON W ,  ROBEY WILLIAM GERARD ,  DALUGA CYNTHIA K ,  KNIGGE KEVIN M ,  STOJAK JOSEPH J II ,  SCHULZE WERNER ,  BRAUN BRIAN P ,  KAPSALIS ANDREAS A ,  STEPHENS JOHN E ,  VALLARI DAVID S

IPC: G01N33/543 ,  G01N33/569 ,  G01N33/68 ,  G01N33/571 ,  G01N33/576

Abstract: An immunoassay which is capable of simultaneously detecting any desired number of antigens of one infectious agent, or combinations of antigens of several infectious agents, or any desired number of immunoglobulins of one infectious agent, or combinations of immunoglobulins of several infectious agents on a single solid support. A test sample is contacted with a solid support on which one or more antigens are immobilized as discrete test sites. Antigen-antibody complexes are formed and detected on the solid support.

公开(公告)号：AU7320594A

公开(公告)日：1995-01-24

申请号：AU7320594

申请日：1994-06-30

Applicant: ABBOTT LAB

Inventor： LEE HELEN H ,  SWANSON PRISCILLA A ,  IDLER KENNETH B ,  ROSENBLATT JOSEPH D ,  CHEN IRVIN S Y ,  GOLDE DAVID W ,  ROBERTSON EUGENE ,  STEPHENS JOHN E ,  CHAN EMERSON W ,  BUYTENDORP MARK H ,  JOHNSON JOAN E ,  MOTLEY CHERYL T ,  EDWARDS MICHELLE ,  TATE CYNTHIA ,  PETERSON BRYAN ,  GUIDINGER PEGGY

IPC: G01N33/53 ,  A61K38/00 ,  C07K14/15 ,  C07K16/10 ,  C12N5/10 ,  C12N7/00 ,  C12N15/09 ,  C12P21/02 ,  C12Q1/70 ,  G01N33/543 ,  G01N33/569 ,  C12N7/02 ,  C07K13/00 ,  C07K15/02 ,  C07K17/00 ,  C07K17/08 ,  C07K17/12

Abstract: The present invention relates generally to a novel human T-cell lymphotropic, or leukemia, virus type II (HTLV-II) isolate designated NRA. HTLV-IINRA was originally isolated from a patient with atypical hairy cell leukemia. Preliminary restriction analysis of this isolate demonstrated that it differs genetically from the prototypical HTLV-II isolate Mo. HTLV-IINRA proviral molecular clones were obtained and the entire nucleotide sequence of the virus ascertained. The claimed invention is particularly directed toward the gp46 and p21e envelope proteins encoded by the env gene. Methods and kits for the detection of HTLV-II antibodies employing these envelope proteins are also described.

公开(公告)号：CA2166291A1

公开(公告)日：1995-01-12

申请号：CA2166291

申请日：1994-06-30

Applicant: UNIV CALIFORNIA ,  ABBOTT LAB

Inventor： GUIDINGER PEGGY ,  BUYTENDORP MARK H ,  EDWARDS MICHELLE ,  GOLDE DAVID W ,  ROSENBLATT JOSEPH D ,  CHAN EMERSON W ,  JOHNSON JOAN E ,  LEE HELEN H ,  ROBERTSON EUGENE ,  TATE CYNTHIA ,  PETERSON BRYAN ,  IDLER KENNETH B ,  SWANSON PRISCILLA A ,  MOTLEY CHERYL T ,  CHEN IRVIN S Y ,  STEPHENS JOHN E

IPC: G01N33/53 ,  A61K38/00 ,  C07K14/15 ,  C07K16/10 ,  C12N5/10 ,  C12N7/00 ,  C12N15/09 ,  C12P21/02 ,  C12Q1/70 ,  G01N33/543 ,  G01N33/569 ,  C07K19/00 ,  C12N9/12 ,  G01N33/577

Abstract: Compositions including lysates, DNA and amino acid sequences derived from HTLV-IINRA are provided. Assays for detecting HTLV infection that employ the disclosed HTLV-IINRA compositions are also provided. Kits for performing HTLV assays are further provided.

公开(公告)号：CA2043689A1

公开(公告)日：1991-12-05

申请号：CA2043689

申请日：1991-05-31

Applicant: ABBOTT LAB

Inventor： CHAN EMERSON W ,  SCHULZE WERNER ,  ROBEY WILLIAM G ,  BRAUN BRIAN P ,  DALUGA CYNTHIA K ,  KAPSALIS ANDREAS A ,  KNIGGE KEVIN M ,  STEPHENS JOHN E ,  STOJAK JOSEPH J II ,  VALLARI DAVID S

IPC: G01N33/543 ,  G01N33/569

Abstract: An immunoassay which is capable of simultaneously detecting any desired number of antigens of one infectious agent, or combinations of antigens of several infectious agents, or any desired number of immunoglobulins of one infectious agent, or combinations of immunoglobulins of several infectious agents on a single solid support. A test sample is contacted with a solid support on which one or more antigens are immobilized as discrete test sites. Antigen-antibody complexes are formed and detected on the solid support.