公开(公告)号：CA2370659A1

公开(公告)日：2000-10-26

申请号：CA2370659

申请日：2000-04-21

Applicant: ABBOTT LAB

Inventor： LYNCH KEVIN J ,  BURGARD EDWARD C ,  JARVIS MICHAEL F ,  VAN BIESEN TIMOTHY ,  KOWALUK ELIZABETH A

IPC: G01N33/53 ,  A61K31/16 ,  A61K31/185 ,  A61K31/675 ,  A61K31/7076 ,  A61K38/00 ,  A61K45/00 ,  A61P25/04 ,  A61P29/02 ,  A61P43/00 ,  C07K14/705 ,  C07K16/28 ,  C12N5/10 ,  C12N15/09 ,  C12N15/12 ,  C12P21/02 ,  C12P21/08 ,  C12Q1/02 ,  C12Q1/68 ,  C12R1/91 ,  G01N33/566

Abstract: The subject invention relates to the P2X3 receptor, methods of modulating th e activity of the P2X3 receptor and to uses of these methods. In particular, such methods may be used, for example, to accelerate the rate of resensitization of a desensitized receptor.