公开(公告)号：WO2007040650A3

公开(公告)日：2007-04-12

申请号：PCT/US2006/018799

申请日：2006-05-12

Applicant: ABBOTT LABORATORIES ,  BRUNCKO, Milan ,  DING, Hong ,  ELMORE, Steven, W. ,  KUNZER, Aaron, R. ,  LYNCH, Christopher, L. ,  MCCELLAN, William, J. ,  PARK, Cheol Min ,  SONG, Xiahong ,  WANG, Xilu

Inventor： BRUNCKO, Milan ,  DING, Hong ,  ELMORE, Steven, W. ,  KUNZER, Aaron, R. ,  LYNCH, Christopher, L. ,  MCCELLAN, William, J. ,  PARK, Cheol Min ,  SONG, Xiahong ,  WANG, Xilu

IPC: C07D295/14 ,  C07D487/08 ,  C07D491/08 ,  A61K31/496 ,  A61P35/00

Abstract: Compounds which inhibit the activity of anti-apoptotic family protein members, compositions containing the compounds and methods of treating diseases during which occur expression one or more than one of an anti?apoptotic family protein member are disclosed.

公开(公告)号：WO2007040650A2

公开(公告)日：2007-04-12

申请号：PCT/US2006/018799

申请日：2006-05-12

Applicant: ABBOTT LABORATORIES ,  BRUNCKO, Milan ,  DING, Hong ,  ELMORE, Steven, W. ,  KUNZER, Aaron, R. ,  LYNCH, Christopher, L. ,  MCCELLAN, William, J. ,  PARK, Cheol Min ,  SONG, Xiahong ,  WANG, Xilu

Inventor： BRUNCKO, Milan ,  DING, Hong ,  ELMORE, Steven, W. ,  KUNZER, Aaron, R. ,  LYNCH, Christopher, L. ,  MCCELLAN, William, J. ,  PARK, Cheol Min ,  SONG, Xiahong ,  WANG, Xilu

IPC: C07D295/14 ,  C07D487/08 ,  C07D491/08 ,  A61K31/496

CPC classification number: C07D295/155 ,  C07D487/08 ,  C07D491/08

Abstract: Compounds which inhibit the activity of anti-apoptotic family protein members, compositions containing the compounds and methods of treating diseases during which occur expression one or more than one of an anti?apoptotic family protein member are disclosed.

Abstract translation: 公开了抑制抗凋亡家族蛋白成员活性的化合物，含有该化合物的组合物和治疗疾病的方法，其中发生表达一种或多种抗凋亡家族蛋白成员。

公开(公告)号：EP1888550A2

公开(公告)日：2008-02-20

申请号：EP06836066.8

申请日：2006-05-12

Applicant: ABBOTT LABORATORIES

Inventor： BRUNCKO, Milan ,  DING, Hong ,  ELMORE, Steven, W. ,  KUNZER, Aaron, R. ,  LYNCH, Christopher, L. ,  MCCELLAN, William, J. ,  PARK, Cheol Min ,  SONG, Xiahong ,  WANG, Xilu

IPC: C07D295/14 ,  C07D487/08 ,  C07D491/08 ,  A61K31/496

CPC classification number: C07D295/155 ,  C07D487/08 ,  C07D491/08

Abstract: Compounds which inhibit the activity of anti-apoptotic family protein members, compositions containing the compounds and methods of treating diseases during which occur expression one or more than one of an anti-apoptotic family protein member are disclosed.