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1.发明公开Benzo-1,3-dioxolyl- and benzofuranyl substituted pyrrolidine derivatives as endothelin antagonists 失效苯并-1,3-二氧杂环戊烯和苯并呋喃基取代的吡咯烷衍生物作为内皮素拮抗剂
公开(公告)号：EP1609790A3
公开(公告)日：2006-01-04
申请号：EP05106190.1
申请日：1997-02-12
Applicant: ABBOTT LABORATORIES
Inventor： Winn, Martin , Henry, Kenneth J. Jr. , Liu, Gang , Wittenberger, Steven J. , King, Steven A. , Boyd, Steven A. , Hutchins, Charles W. , Jae, Hwan-Soo , Tasker, Andrew S. , Von Geldern, Thomas W. , Kester, Jeffrey A. , Sorensen, Bryan K. , Szczepankiewicz, Bruce G.
IPC: C07D405/04 , C07D405/12 , A61K31/40 , A61K31/41 , A61K31/435
CPC classification number: C07D401/04 , C07D207/16 , C07D405/04 , C07D405/12 , C07D405/14 , Y02P20/55
Abstract: A compound of formula (I), or a pharmaceutically acceptable salt thereof is disclosed, as well as processes for and intermediates in the preparation thereof, and a method of antagonizing endothelin.
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2.发明公开Benzo-1,3-dioxolyl- and benzofuranyl substituted pyrrolidine derivatives as endothelin antagonists 失效苯并-1,3-二恶唑基 - 和苯并呋喃基取代的吡咯烷衍生物内皮素拮抗剂
公开(公告)号：EP1609790A2
公开(公告)日：2005-12-28
申请号：EP05106190.1
申请日：1997-02-12
Applicant: ABBOTT LABORATORIES
Inventor： Winn, Martin , Henry, Kenneth J. Jr. , Liu, Gang , Wittenberger, Steven J. , King, Steven A. , Boyd, Steven A. , Hutchins, Charles W. , Jae, Hwan-Soo , Tasker, Andrew S. , Von Geldern, Thomas W. , Kester, Jeffrey A. , Sorensen, Bryan K. , Szczepankiewicz, Bruce G.
IPC: C07D405/04 , C07D405/12 , A61K31/40 , A61K31/41 , A61K31/435
CPC classification number: C07D401/04 , C07D207/16 , C07D405/04 , C07D405/12 , C07D405/14 , Y02P20/55
Abstract: A compound of formula (I), or a pharmaceutically acceptable salt thereof is disclosed, as well as processes for and intermediates in the preparation thereof, and a method of antagonizing endothelin.
Abstract translation: 公开了式（I）化合物或其药学上可接受的盐，以及其制备方法和中间体，以及拮抗内皮素的方法。
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