中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

4 records (took 0.024 seconds)

    METHODS AND COMPOSITIONS ASSOCIATED WITH ADMINISTRATION OF AN EXTRACT OF GANODERMA LUCIDUM
    1.
    发明申请
    METHODS AND COMPOSITIONS ASSOCIATED WITH ADMINISTRATION OF AN EXTRACT OF GANODERMA LUCIDUM 审中-公开
    与甘草提取物相关的方法和组合物

    公开(公告)号：WO2006044616A3

    公开(公告)日：2006-08-24

    申请号：PCT/US2005036961

    申请日：2005-10-14

    Applicant: ACADEMIA SINICA ,  WONG CHI-HUEY ,  HSU HSIEN-YEH ,  HUA KUO-FENG ,  LIN CHUN-HUNG ,  HSU JASON ,  CHEN SHUI-TEIN ,  LIN KUO-I ,  YANG WEN-BIN ,  YU JOHN ,  YU ALICE

    Inventor： WONG CHI-HUEY ,  HSU HSIEN-YEH ,  HUA KUO-FENG ,  LIN CHUN-HUNG ,  HSU JASON ,  CHEN SHUI-TEIN ,  LIN KUO-I ,  YANG WEN-BIN ,  YU JOHN ,  YU ALICE

    IPC: A01N65/00

    CPC classification number: A61K36/074

    Abstract: A fucose-containing glycoprotein fraction obtainable from an extract of Ganoderma Lucidum Reishi, compositions comprising the fuconse-containing glycoprotein fraction, a method to mediate immunomodulating events associated with IL-1 gene expression, a method to stimulate the expression of an inflammatory cytokine, a method to modulate protein kinase pathways associated with inflammatory cytokine Interleukin 1, a method to induce a TLR mediated event; a method to modulate differentiation of a mononuclear cell, a method to enhance cytotoxicity of an NK cell against an NK-sensitive tumor cell, a method to activate the expression of cytokines, a method to induce Blimp-1 expression in a mouse splenic B cell or human B cell, human mature splenocytes or dendritic cell, a method to inhibit LPS induced nitric oxide production in macrophages, a method to activate spleen cells proliferation, and a method to modify the proteome of a spleen cell.

    Abstract translation: 从灵芝提取物获得的含岩藻糖的糖蛋白部分，包含含有蛋白质的糖蛋白部分的组合物，介导与IL-1基因表达相关的免疫调节事件的方法，刺激炎性细胞因子的表达的方法 调节与炎症细胞因子相关的蛋白激酶途径白细胞介素1的方法，诱导TLR介导的事件的方法; 调节单核细胞分化的方法，增强NK细胞对NK敏感性肿瘤细胞的细胞毒性的方法，激活细胞因子表达的方法，在小鼠脾B细胞中诱导Blimp-1表达的方法 或人B细胞，人成熟脾细胞或树突状细胞，抑制巨噬细胞中LPS诱导的一氧化氮产生的方法，活化脾细胞增殖的方法以及修饰脾细胞的蛋白质组的方法。

    LONGEVITY-PROMOTING EFFECTS OF ACETIC ACID AND REISHI POLYSACCHARIDE
    3.
    发明申请
    LONGEVITY-PROMOTING EFFECTS OF ACETIC ACID AND REISHI POLYSACCHARIDE 审中-公开
    长寿命促进醋酸和食用多糖的促进作用

    公开(公告)号：WO2009129424A3

    公开(公告)日：2009-12-23

    申请号：PCT/US2009040879

    申请日：2009-04-16

    Applicant: ACADEMIA SINICA ,  YANG WEN-BIN ,  WONG CHI-HUEY ,  CHIOU SHYH-HORNG ,  CHUANG MING-HONG

    Inventor： YANG WEN-BIN ,  WONG CHI-HUEY ,  CHIOU SHYH-HORNG ,  CHUANG MING-HONG

    IPC: C12N1/38 ,  C12N1/10 ,  C12N15/01 ,  C12R1/90

    CPC classification number: G01N33/5085 ,  A61K36/07 ,  A61K36/074 ,  G01N2333/43534 ,  G01N2333/70596 ,  A61K2300/00

    Abstract: A composition of acetic acid and a composition of acetic acid and RF3 effecting expression of DAF-16 in C. elegans, wherein the at least acetic acid and the RF3 polysaccharide is effective to increase the life-span of C. elegans or humans. A method of regulating DAF-16 expression, comprising: administering a composition comprising at least acetic acid and RF3 polysaccharide; providing the composition to at least one receptor on a surface of a cell; causing an increase in expression of DAF-16. A method for screening a series of compounds or constituents parts of compounds including some antioxidant vitamins, traditional herb medicines, and vinegars using C. elegans as a live organism model to examine to determine if they have an impact the lifespan of C elegans and the underlying mechanism(s) thereof.

    Abstract translation: 乙酸组合物和乙酸组合物和RF3在秀丽隐杆线虫中实现DAF-16的表达，其中所述至少乙酸和RF3多糖对于增加秀丽隐杆线虫或人的寿命是有效的。 一种调节DAF-16表达的方法，包括：给予至少包含乙酸和RF3多糖的组合物; 将组合物提供给细胞表面上的至少一个受体; 导致DAF-16表达增加。 筛选一系列化合物或化合物的组成部分，包括一些抗氧化维生素，传统草药和醋，使用线虫作为活体生物模型来检查以确定它们是否影响线虫的寿命和潜在的 机制。

Patent Agency Ranking