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公开(公告)号：CA2580548A1
公开(公告)日：2006-04-06
申请号：CA2580548
申请日：2005-09-27
Applicant: ACEA BIOSCIENCES INC
Inventor： XU XIAO , WANG XIAOBO , ATIENZA JOSEPHINE , ABASSI YAMA A
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公开(公告)号：CA2575573A1
公开(公告)日：2006-02-16
申请号：CA2575573
申请日：2005-08-04
Applicant: ACEA BIOSCIENCES INC
Inventor： ABASSI YAMA A , YU NAICHEN , WANG XIAOBO , ATIENZA JOSEPHINE , XU XIAO
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公开(公告)号：CA2760941C
公开(公告)日：2019-07-23
申请号：CA2760941
申请日：2010-05-05
Applicant: ACEA BIOSCIENCES INC
Inventor： WANG XIAOBO , OUYANG WEI , LI NAN , XI BIAO , ABASSI YAMA A , XU XIAO
Abstract: Devices and methods for performing extracellular recording of cells, such as excitable cells, cardiomyocytes, and cardiomyocyte precursor cells is provided. An exemplary device includes a nonconductive substrate forming or provided as a base of one or more wells; a recording electrode positioned on the substrate within the well, wherein the recording electrode is accessible to cells when a cell sample is added to the device; and a reference electrode positioned within the well in a cell-free zone, the cell-free zone characterized as free from contact with cells when the cell sample is added to the device, thereby preventing contact between cells and the reference electrode.
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公开(公告)号：CA2760941A1
公开(公告)日：2010-11-11
申请号：CA2760941
申请日：2010-05-05
Applicant: ACEA BIOSCIENCES INC
Inventor： WANG XIAOBO , OUYANG WEI , LI NAN , XI BIAO , ABASSI YAMA A , XU XIAO
Abstract: Devices and methods for performing extracellular recording of cells, such as excitable cells, cardiomyocytes, and cardiomyocyte precursor cells is provided. An exemplary device includes a nonconductive substrate forming or provided as a base of one or more wells; a recording electrode positioned on the substrate within the well, wherein the recording electrode is accessible to cells when a cell sample is added to the device; and a reference electrode positioned within the well in a cell-free zone, the cell-free zone characterized as free from contact with cells when the cell sample is added to the device, thereby preventing contact between cells and the reference electrode.
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公开(公告)号：HK1258798A1
公开(公告)日：2019-11-22
申请号：HK19101162
申请日：2019-01-23
Applicant: ACEA BIOSCIENCES INC
Inventor： WANG XIAOBO , ABASSI YAMA A , LI NAN , MUIR LINCOLN , XU XIAO
IPC: C12M20060101 , C12N20060101 , H01M20060101
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Patent Agency Ranking6.发明公开DYNAMIC MONITORING OF ACTIVATION OF G-PROTEIN (GPCR) AND RECEPTOR TYROSINE KINASE (RTK) IN LIVING CELLS USING REAL-TIME MICROELECTRONIC CELL SENSING TECHNOLOGY 有权动态监测G蛋白（GPCR）与受体酪氨酸激酶（RTK）在活使用微电子REAL-TIME CELL探测技术活化细胞
公开(公告)号：EP1773979A4
公开(公告)日：2013-04-24
申请号：EP05786773
申请日：2005-08-04
Applicant: ACEA BIOSCIENCES INC
Inventor： ABASSI YAMA A , YU NAICHEN , ATIENZA JOSEPHINE , XU XIAO , WANG XIAOBO
CPC classification number: G01N33/4836
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公开(公告)号：EP2427543A4
公开(公告)日：2017-11-29
申请号：EP10772804
申请日：2010-05-05
Applicant: ACEA BIOSCIENCES INC
Inventor： WANG XIAOBO , OUYANG WEI , LI NAN , XI BIAO , ABASSI YAMA A , XU XIAO
IPC: G01N33/487
CPC classification number: G01N33/48728
Abstract: Devices and methods for performing extracellular recording of cells, such as excitable cells, cardiomyocytes, and cardiomyocyte precursor cells is provided. An exemplary device includes a nonconductive substrate forming or provided as a base of one or more wells; a recording electrode positioned on the substrate within the well, wherein the recording electrode is accessible to cells when a cell sample is added to the device; and a reference electrode positioned within the well in a cell-free zone, the cell-free zone characterized as free from contact with cells when the cell sample is added to the device, thereby preventing contact between cells and the reference electrode.
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8.发明公开DEVICE AND METHOD FOR ELECTROPORATION-BASED DELIVERY OF MOECULES INTO CELLS AND DYNAMIC MONITORING OF CELL RESPONSES 有权DEVICE AND METHOD FOR分子的ON ELEKTROPORATIONSBASIS细胞和细胞应答动态监测摄食
公开(公告)号：EP1815025A4
公开(公告)日：2011-10-12
申请号：EP05852157
申请日：2005-11-23
Applicant: ACEA BIOSCIENCES INC
Inventor： ABASSI YAMA A , WANG XIAOBO , ATIENZA JOSEPHINE , XU XIAO , XU JUNQUAN
CPC classification number: G01N33/5008 , C12M35/02 , C12N15/87 , G01N15/12 , G01N33/48728
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9.发明公开DYNAMIC MONITORING OF CELL ADHESION AND SPREADING USING THE RT-CES SYSTEM 审中-公开细胞粘附动态监视与分布使用RT-CES-SYSTEMS
公开(公告)号：EP1800312A4
公开(公告)日：2011-10-05
申请号：EP05812268
申请日：2005-09-27
Applicant: ACEA BIOSCIENCES INC
Inventor： ABASSI YAMA A , ATIENZA JOSEPHINE , XU XIAO , WANG XIAOBO
IPC: G11C11/00 , C12M1/34 , G01N29/036 , H01M4/50
CPC classification number: G01N29/036 , G01N2291/0257
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10.发明公开USE OF IMPEDANCE-BASED CYTOLOGICAL PROFILING TO CLASSIFY CELLULAR RESPONSE PROFILES UPON EXPOSURE TO BIOLOGICALLY ACTIVE AGENTS 审中-公开使用细胞基于阻抗的分析信息分类细胞反应型材除了生理活性物质
公开(公告)号：EP2064644A4
公开(公告)日：2010-12-29
申请号：EP07838594
申请日：2007-09-20
Applicant: ACEA BIOSCIENCES INC
Inventor： WANG XIAOBO , ABASSI YAMA A , ZHANG WENFU , XU XIAO
IPC: G06F19/24
CPC classification number: G01N33/54373 , G01N33/5005 , G01N33/5438 , G06F19/24
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