公开(公告)号：WO2018025265A2

公开(公告)日：2018-02-08

申请号：PCT/IL2017/050853

申请日：2017-08-02

Applicant: ADOM, ADVANCED OPTICAL TECHNOLOGIES LTD.

Inventor： ARIELI, Yoel ,  COHEN, Yoel ,  EPSTEIN, Shlomi ,  ARBEL, Dror ,  GEFEN, Ra'anan

IPC: A61B3/10

Abstract: Apparatus and methods are described for performing tear film structure measurement on a tear film of an eye of a subject. A broadband light source (100) is configured to generate broadband light. A spectrometer (250) is configured to measure a spectrum of light of the broadband light that is reflected from at least one spot on the tear film, the spot having a diameter of between 100 microns and 240 microns. A computer processor (28) is coupled to the spectrometer and configured to determine a characteristic of the tear film based upon the spectrum of light measured by the spectrometer. Other applications are also described.

Abstract translation: 描述了用于在受试者的眼睛的泪膜上执行泪膜结构测量的设备和方法。 宽带光源（100）被配置为产生宽带光。 分光计（250）被配置为测量从泪膜上的至少一个点反射的宽带光的光谱，该点具有在100微米与240微米之间的直径。 计算机处理器（28）耦合到光谱仪并且被配置为基于由光谱仪测量的光谱来确定泪膜的特性。 还介绍了其他应用程序。

公开(公告)号：WO2018025265A3

公开(公告)日：2018-02-08

申请号：PCT/IL2017/050853

申请日：2017-08-02

Applicant: ADOM, ADVANCED OPTICAL TECHNOLOGIES LTD.

Inventor： ARIELI, Yoel ,  COHEN, Yoel ,  EPSTEIN, Shlomi ,  ARBEL, Dror ,  GEFEN, Ra'anan

IPC: A61B3/10

Abstract: Apparatus and methods are described for performing tear film structure measurement on a tear film of an eye of a subject. A broadband light source (100) is configured to generate broadband light. A spectrometer (250) is configured to measure a spectrum of light of the broadband light that is reflected from at least one spot on the tear film, the spot having a diameter of between 100 microns and 240 microns. A computer processor (28) is coupled to the spectrometer and configured to determine a characteristic of the tear film based upon the spectrum of light measured by the spectrometer. Other applications are also described.

公开(公告)号：WO2015132788A2

公开(公告)日：2015-09-11

申请号：PCT/IL2015/050232

申请日：2015-03-04

Applicant: ADOM, ADVANCED OPTICAL TECHNOLOGIES LTD.

Inventor： ARIELI, Yoel ,  COHEN, Yoel ,  EPSTEIN, Shlomi ,  ARBEL, Dror

CPC classification number: A61B3/101 ,  A61B3/0025 ,  A61B3/1005 ,  A61B3/152 ,  G01B9/02021 ,  G01B9/02025 ,  G01B9/02027 ,  G01B9/02044 ,  G01B9/02087 ,  G01B9/0209 ,  G01B11/06 ,  G01B11/0625 ,  G01B11/0675 ,  G01B2290/45 ,  G01N21/274 ,  G01N2201/066 ,  G01N2201/127 ,  G02B3/08

Abstract: In a system and method for performing tear film structure measurement and evaporation rate measurements a broadband light source illuminates the tear film and a spectrometer measures respective spectra of reflected light from at least one point of the tear film. A color camera obtains a large field of view image of the tear film so as to obtain color information for all points of the tear film imaged by the color camera and an autofocusing mechanism focusses the color camera and the spectrometer. A processing unit coupled to the camera and to the spectrometer calibrates the camera so that the color obtained by the camera at the at least one point measured by the spectrometer matches the color of the spectrometer at the same point, and determines from the color of each point of the calibrated camera the thickness of the lipids at the respective point.

Abstract translation: 在用于执行泪膜结构测量和蒸发速率测量的系统和方法中，宽带光源照射泪膜并且光谱仪测量来自泪膜的至少一个点的反射光的各个光谱。 彩色照相机获得泪膜的大视场图像，以获得由彩色照相机成像的泪膜的所有点的颜色信息，并且自动聚焦机构聚焦彩色照相机和光谱仪。 耦合到照相机和光谱仪的处理单元校准照相机，使得由照相机在由光谱仪测量的至少一个点处获得的颜色与在相同点处的光谱仪的颜色匹配，并且从每个照相机的颜色确定 校准摄像头的点在相应点的脂质厚度。

公开(公告)号：EP3434173A1

公开(公告)日：2019-01-30

申请号：EP18192052.1

申请日：2015-03-04

Applicant: ADOM Advanced Optical Technologies Ltd.

Inventor： ARIELI, Yoel ,  COHEN, Yoel ,  EPSTEIN, Shlomi ,  ARBEL, Dror

IPC: A61B3/10 ,  G01J3/00

Abstract: In a system and method for performing tear film structure measurements a broadband light source illuminates the tear film on a cornea of the eye and a spectrometer measures respective spectra of reflected light from at least one point of the cornea. A color camera obtains a large field of view image of the cornea so as to obtain color information for all points of the tear film imaged by the color camera. A processing unit coupled to the camera and to the spectrometer is configured, using 3D electromagnetic simulation, to analyze the reflected light received by the spectrometer and the camera, by iteratively comparing the received reflected light to a simulated measurement until a best fit is obtained for corneal structure parameters

公开(公告)号：EP3493727A2

公开(公告)日：2019-06-12

申请号：EP17761602.6

申请日：2017-08-02

Applicant: ADOM Advanced Optical Technologies Ltd.

Inventor： ARIELI, Yoel ,  COHEN, Yoel ,  EPSTEIN, Shlomi ,  ARBEL, Dror ,  GEFEN, Ra'anan

IPC: A61B3/10

公开(公告)号：EP3113668B1

公开(公告)日：2018-09-26

申请号：EP15753474.4

申请日：2015-03-04

Applicant: ADOM Advanced Optical Technologies Ltd.

Inventor： ARIELI, Yoel ,  COHEN, Yoel ,  EPSTEIN, Shlomi ,  ARBEL, Dror

IPC: A61B3/10

CPC classification number: A61B3/101 ,  A61B3/0025 ,  A61B3/10 ,  A61B3/1005 ,  A61B3/152 ,  G01B9/02021 ,  G01B9/02025 ,  G01B9/02027 ,  G01B9/02044 ,  G01B9/02087 ,  G01B9/0209 ,  G01B11/06 ,  G01B11/0625 ,  G01B11/0675 ,  G01B2290/45 ,  G01J3/00 ,  G01N21/274 ,  G01N2201/066 ,  G01N2201/127 ,  G02B3/08 ,  G06T2207/30041

Abstract: A system and method are described for performing tear film structure measurement. A broadband light source illuminates the tear film. A spectrometer measures respective spectra of reflected light from at least one point of the tear film. A color camera performs large field of view imaging of the tear film, so as to obtain color information for all points of the tear film imaged by the color camera. A processing unit calibrates the camera at the point measured by the spectrometer so that the color obtained by the camera at the point matches the color of the spectrometer at the same point. The processing unit determines, from the color of respective points of the calibrated camera, thicknesses of one or more layers of the tear film at the respective points. Other applications are also described.

公开(公告)号：EP3113668A2

公开(公告)日：2017-01-11

申请号：EP15753474.4

申请日：2015-03-04

Applicant: ADOM Advanced Optical Technologies Ltd.

Inventor： ARIELI, Yoel ,  COHEN, Yoel ,  EPSTEIN, Shlomi ,  ARBEL, Dror

IPC: A61B3/10

CPC classification number: A61B3/101 ,  A61B3/0025 ,  A61B3/1005 ,  A61B3/152 ,  G01B9/02021 ,  G01B9/02025 ,  G01B9/02027 ,  G01B9/02044 ,  G01B9/02087 ,  G01B9/0209 ,  G01B11/06 ,  G01B11/0625 ,  G01B11/0675 ,  G01B2290/45 ,  G01N21/274 ,  G01N2201/066 ,  G01N2201/127 ,  G02B3/08

Abstract: Apparatus and methods are described for performing structure measurement on a tear film of an eye of a subject. At least a portion of a surface of the tear film is illuminated using a broadband light source. A spectrum of light of the broadband light that is reflected from at least one point of the tear film is measured, using a spectrometer. Color information for a plurality of points of the tear film is obtained, by imaging a field of view of the tear film using a color camera. Using a processing unit, data from the color camera and data from the spectrometer that are indicative of characteristics of the tear film are received, and based upon a combination of the data received from the color camera and the data received from the spectrometer, an output is generated that is indicative of a structure of the tear film.

Abstract translation: 一种系统和方法被描述用于执行泪膜结构的测量。 宽带光源照亮撕裂电影。 从撕裂成膜中的至少一个点的反射光的光谱仪的措施respectivement光谱。 彩色相机执行视图撕裂电影的成像的大视场，从而获得用于撕裂由彩色摄像机薄膜成像的所有点的颜色信息。 处理单元校准所述照相机在由光谱仪测量所以没有在点由照相机获得的颜色光谱仪在相同点处的颜色相匹配的点。 该处理单元确定的地雷，从校准的相机的respectivement点的颜色，撕裂的一个或多个层的厚度的膜在respectivement点。 其他的应用是如此描述。