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公开(公告)号：US10278701B2
公开(公告)日：2019-05-07
申请号：US13730259
申请日：2012-12-28
Applicant: Ethicon, Inc. , Agency for Science Technology and Research
Inventor： Sriram Natarajan , Joseph J. Hammer , Kevin Cooper , Murty Vyakarnam , Hong Yee Low , Isabel Rodriguez , Chee Tiong Lim , Audrey Yoke Yee Ho
Abstract: An implant having an adhesive structure comprising a planar surface having two sides and rectangular cuboid-based protrusions having pyramidal tips extending from at least one of said sides, optionally having a porous basic supporting structure, and methods of making and using such implants.
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公开(公告)号：US20190094561A1
公开(公告)日：2019-03-28
申请号：US16198386
申请日：2018-11-21
Inventor： Beng Soon Tan , Chee Fatt Frank Chan , Yun Xu , Bee Khuan Jaslyn Law , Yee Chong Loke , Hong Yee Low
Abstract: According to one aspect of the invention, there is provided a method of forming a film with a lenticular lens array, the method comprising providing a substrate; providing a mold having a plurality of nano-scale to micro-scale cavities that form the lenticular lens array on the substrate; having the mold contact the substrate; and forming the lenticular lens array by allowing portions of the substrate to partially fill the plurality of cavities.
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公开(公告)号：US09955687B2
公开(公告)日：2018-05-01
申请号：US14402054
申请日：2013-05-20
Applicant: Agency for Science, Technology and Research , Ngee Ann Polytechnic , Temasek Polytechnic , Singapore Polytechnic
Inventor： Karen Siew Ling Chong , Yeong Yuh Lee , Seok Hong Goh , Kevin Beng Chin Khaw , Ryan Chaw , Hong Yee Low , Adrian Yeo , Weng Keong Choy , Han Liat Loh
CPC classification number: A01N25/34 , B63B59/045 , C09D5/1681 , Y10T428/24802
Abstract: A surface on a polymeric film having an array of patterned structures, wherein the array of patterned structures influences fluid flow of the surface and causes reduced attachment of a biological material.
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公开(公告)号：US20150104622A1
公开(公告)日：2015-04-16
申请号：US14402054
申请日：2013-05-20
Applicant: Agency for Science, Technology and Research , Ngee Ann Polytechnic , Temasek Polytechnic , Singapore Polytechnic
Inventor： Karen Siew Ling Chong , Yeong Yuh Lee , Seok Hong Goh , Kevin Beng Chin Khaw , Ryan Chaw , Hong Yee Low , Adrian Yeo , Weng Keong Choy , Han Liat Loh
IPC: A01N25/34
CPC classification number: A01N25/34 , B63B59/045 , C09D5/1681 , Y10T428/24802
Abstract: A surface on a polymeric film having an array of patterned structures, wherein the array of patterned structures influences fluid flow of the surface and causes reduced attachment of a biological material.
Abstract translation: 具有图案化结构阵列的聚合物膜上的表面，其中图案化结构的阵列影响表面的流体流动并导致生物材料的附着减少。
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5.发明申请SUPER-HYDROPHOBIC HIERARCHICAL STRUCTURES, METHOD OF FORMING THEM AND MEDICAL DEVICES INCORPORATING THEM 审中-公开超级疏水分层结构，其形成方法和与其配套的医疗器械公开(公告)号：US20140120314A1
公开(公告)日：2014-05-01
申请号：US14139673
申请日：2013-12-23
Inventor： Audrey Yoke Yee Ho , Isabel Rodriguez , Hong Yee Low , Emma Kim Luong-Van , Sriram Natarajan , Noha Elmouelhi , Kevin Cooper , Chee Tiong Lim
IPC: A61L31/14
CPC classification number: A61L31/14 , A61L27/50 , A61L27/56 , A61L31/146 , A61L2400/18 , B82Y30/00 , B82Y40/00 , Y10T428/24355
Abstract: Synthetic polymer substrates comprising a hierarchical surface structure of multiple domes and multiple pillars on said domes, wherein said substrate is a synthetic polymer film, said domes have diameters in the range from about 5 μm to about 400 μm, heights in the range from about 2.5 μm and about 500 μm, and said pillars have diameters in the range from about 20 nm to about 5 μm and aspect ratios of from about 2 to about 50, and methods of making and using them.
Abstract translation: 合成聚合物基材，其包含在所述圆顶上的多个圆顶和多个柱的分层表面结构，其中所述基材是合成聚合物膜，所述圆顶的直径在约5μm至约400μm的范围内，高度在约2.5 μm和约500μm，并且所述柱具有在约20nm至约5μm范围内的直径和约2至约50的纵横比，以及制造和使用它们的方法。
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Patent Agency Ranking
公开(公告)号：US20130204392A1
公开(公告)日：2013-08-08
申请号：US13755529
申请日：2013-01-31
Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH , NATIONAL UNIVERSITY OF SINGAPORE , NATIONAL UNIVERSITY HEALTH SYSTEM
Inventor： Bee Khuan Jaslyn Law , Ai Yu He , Hong Yee Low , Yingnan Wu , Zheng Yang , Eng Hin Lee
CPC classification number: A61K35/32 , C12N5/0068 , C12N5/0655 , C12N2502/1352 , C12N2533/30 , C12N2535/00
Abstract: There is provided a method for promoting stem cell chondrogenesis, comprising the step of culturing a population of stem cells on a plurality of imprints disposed on a substrate, the imprints being configured to selectively promote chondrogenesis of the stem cells.
Abstract translation: 提供了一种用于促进干细胞软骨形成的方法，包括在设置在基底上的多个印记上培养一群干细胞的步骤，所述印记被配置为选择性地促进干细胞的软骨形成。
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公开(公告)号：US10890783B2
公开(公告)日：2021-01-12
申请号：US16198386
申请日：2018-11-21
Inventor： Beng Soon Tan , Chee Fatt Frank Chan , Yun Xu , Bee Khuan Jaslyn Law , Yee Chong Loke , Hong Yee Low
Abstract: According to one aspect of the invention, there is provided a method of forming a film with a lenticular lens array, the method comprising providing a substrate; providing a mold having a plurality of nano-scale to micro-scale cavities that form the lenticular lens array on the substrate; having the mold contact the substrate; and forming the lenticular lens array by allowing portions of the substrate to partially fill the plurality of cavities.
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公开(公告)号：US09362126B2
公开(公告)日：2016-06-07
申请号：US13625400
申请日：2012-09-24
Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
Inventor： Ramakrishnan Ganesan , Jarrett Dumond , M. S. M. Saifullah , Su Hui Lim , Hazrat Hussain , Hong Yee Low
IPC: G03F7/00 , H01L21/283 , C23C18/04 , C23C18/06 , C23C18/12 , B81C1/00 , B82Y40/00 , G03F7/004 , G03F7/027 , B82Y10/00 , H01L29/06
CPC classification number: H01L21/283 , B81C1/0046 , B81C2201/0152 , B82Y10/00 , B82Y40/00 , C23C18/04 , C23C18/06 , C23C18/1216 , G03F7/0002 , G03F7/0043 , G03F7/027 , H01L29/0676
Abstract: There is provided a process for making a patterned metal oxide structure comprising the step of heating an imprint structure comprising a polymerized organometallic compound to remove organic material and thereby form the patterned metal oxide structure, wherein the imprint structure is formed by polymerizing a resist mixture comprising at least one olefinic polymerizable compound and a polymerizable organometallic compound having, e.g., at least one carboxylate of Formula 1: wherein n is 1-12; and each R is independently selected from the group consisting of hydrogen, alkyl, alkenyl, alkynyl, cycloakyl, cycloakenyl, aryl, and aralkyl.
Abstract translation: 提供了一种用于制造图案化金属氧化物结构的方法，其包括加热包含聚合的有机金属化合物的压印结构以除去有机材料并由此形成图案化的金属氧化物结构的步骤，其中通过聚合抗蚀剂混合物形成压印结构，所述抗蚀剂混合物包含 至少一种烯属聚合性化合物和具有例如至少一种式1羧酸酯的可聚合的有机金属化合物：其中n为1-12; 并且每个R独立地选自氢，烷基，烯基，炔基，环烷基，环辛基，芳基和芳烷基。
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公开(公告)号：US20130206330A1
公开(公告)日：2013-08-15
申请号：US13841561
申请日：2013-03-15
Inventor： Sriram Natarajan , Joseph Hammer , Kevin Cooper , Murty Vyakarnam , Hong Yee Low , Isabel Rodriguez , Chee Tiong Lim , Audrey Yoke Yee Ho
IPC: A61F2/00
CPC classification number: A61F2/0063 , A61B2017/00871 , A61B2017/00938 , A61B2017/00942 , A61B2017/00951 , A61L31/048 , A61L31/06 , A61L31/10 , B29C33/52 , C09J7/21 , C09J7/30 , C09J2201/32 , C09J2400/263 , C08L23/12 , C08L67/04
Abstract: A laminate and process of making the laminate is disclosed comprising: a surgical mesh having first and second surfaces; and an adhesive structure having adhesive and non-adhesive surfaces, wherein the non-adhesive surface of the adhesive structure is laminated to at least one of said first and second surfaces of said surgical mesh, and the adhesive surface of said adhesive structure has protrusions extending therefrom comprising a resin having a Young's modulus of greater than 17 MPa, which protrusions are of sufficiently low diameter to promote adhesion by increasing physical attractive forces between the adhesive structure and a target surface, as measured by shear adhesion.
Abstract translation: 公开了层压体和制造层压体的方法，包括：具有第一和第二表面的外科手术网; 以及具有粘合剂和非粘合剂表面的粘合剂结构，其中粘合剂结构的非粘合表面被层压到所述外科手术网的所述第一和第二表面中的至少一个上，并且所述粘合剂结构的粘合剂表面具有延伸的突起 其包含杨氏模量大于17MPa的树脂，该突起的直径足够小，以通过剪切粘合力测量来增加粘合剂结构和目标表面之间的物理吸引力来促进粘合。
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公开(公告)号：US10151863B2
公开(公告)日：2018-12-11
申请号：US14420833
申请日：2013-08-12
Inventor： Chee Fatt Chan , Beng Soon Tan , Yun Xu , Bee Khuan Jaslyn Law , Hong Yee Low
Abstract: According to one aspect of the invention, there is provided an optical grating comprising a substrate comprising a plurality of protrusions with a space in between any two adjacent protrusions; and a cap provided on at least one of the plurality of protrusions at an end that is furthest from the substrate, wherein the cap has a higher degree of optical attenuation compared to the substrate material and wherein the combination of each protrusion and the respective cap thereon has a generally symmetric cross-sectional profile.
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