公开(公告)号：JPH03261799A

公开(公告)日：1991-11-21

申请号：JP6080190

申请日：1990-03-12

Applicant: AGENCY IND SCIENCE TECHN

Inventor： SASAKI MAKOTO ,  MATSUZAKI SANAE ,  NIWA YOSHIO ,  ISHIKAWA KEIICHIRO ,  IKEDA YOSHIKAZU ,  ISHIGAMI YUTAKA

IPC: C07K7/06 ,  C09K11/06

Abstract: NEW MATERIAL:A cyclic peptide pyrenacyl ester expressed by the formula. USE:A medium for research such as peptide type environmental probes, molecular aggregates, various media and biomembranes, etc. PREPARATION:For example, the carboxyl group of the terminal leucine residues in 3-hydroxy-13-methyltetradecanoyl-L-glutamyl-L-leucyl-D-leucyl-L-valyl-L- aspartyl-D-leucyl-L-leucylpeptide and-3-hydroxyl group are subjected to cyclodehydration to provide surfactin composed of an amphiphatic cyclic peptide having a lactone structure, which is then dissolved in acetonitrile and reacted with 1-bromoacetylpyrene in the presence of diisopropylethylamine to afford a crude product. The resultant crude product is subsequently purified by silica gel column chromatography to afford surfactin pyrenacyl ester expressed by the formula.

公开(公告)号：JPH02236461A

公开(公告)日：1990-09-19

申请号：JP5899289

申请日：1989-03-10

Applicant: AGENCY IND SCIENCE TECHN

Inventor： MIZUNO MASAKI ,  HAYAKAWA HIROSHI ,  SHIN SHIGEMITSU ,  MATSUZAKI SANAE

IPC: G01R1/06 ,  G01R27/02

Abstract: PURPOSE:To perform measurement superior in reproducibility by providing a measuring part and a stage and arranging the measuring part at least in the vicinity of the stage. CONSTITUTION:A measuring part 22 and a stage 1 which holds the measuring part 22 and is made of a good heat conductor are provided, and the measuring part 22 is arranged at least in the vicinity of the stage 1. A sample attaching part which elastically presses plural terminals 6 for power supply and taking-out of a detection signal to a sample 2 to fix the sample 2 and a connecting means which connects terminals 6 and a measuring circuit are provided, and the stage 1 is provided with a temperature control means which keeps the stage 1 at a prescribed temperature. Ohmic contact to obtain a linear voltage-current characteristic is obtained at the time of connection between the sample and an electrode, and measured results superior in reproducibility are obtained. Further, the sample 2 generated in vacuum like a vapor-deposited film is measured without being taken out from the vacuum.