Abstract:
PROBLEM TO BE SOLVED: To manufacture a SPR system not limited to use of a transparent glass micro fluid cartridge or a sensor chip. SOLUTION: A micro fluid system is provided with the sensor chip 14 and a SPR photodetector 16. The sensor chip 14 can be formed from a non-translucent material such as polyimide and silicon. A light other than a visible light generated by the SPR photodetector 16 passes through a surface plasmon generating layer 26 on the sensor chip, and implements an interaction. COPYRIGHT: (C)2006,JPO&NCIPI
Abstract:
PROBLEM TO BE SOLVED: To provide an improved fluid technology which is capable of using gradient liquid chromatography and reducing the amount of waste liquid, free of complications, has reproducibility, and shortens the delay time. SOLUTION: A fluidic device is provided with a plurality of fluid-transporting features, extending from a common inlet to a common outlet, and a means for effecting a fluid flow through the fluid-transporting features. Each feature has a differing fluid dwell time. The means for effecting a fluid flow cooperates with the fluid-transporting features, merges fluids from the fluid-transporting features, and produces an output stream from the common outlet. The output stream exhibits at least one desired characteristic generated as the result of the differing dwell times. It is thereby possible to generate a stream of a micro-volume flow rate and to obtain a smooth gradient in gradient liquid chromatography also. COPYRIGHT: (C)2007,JPO&INPIT
Abstract:
PROBLEM TO BE SOLVED: To provide a micro fluidic separation device reduced in broadening of a band. SOLUTION: The present invention provides the fluidic separation device 10 and method capable of reducing sample broadening. A column 25 is arranged in a downstream of a holding chamber 53, and a fluid supply means provides a fluid flow effective to convey a sample along a flow passage extended from the holding chamber up to the separation column. A sample is usually converged in the flow passage in an upstream of the separation column. An electrospray mass spectrometer may be provided optionally, and may be used in microfluid application. COPYRIGHT: (C)2007,JPO&INPIT
Abstract:
A fluid separation system (10) for separating compounds of a sample fluid in a mobile phase comprises a detector (50) adapted to detect separated compounds by pro viding an optical stimulus signal to the sample fluid and receiving a response signal to the optical stimulus signal. The detector (50) comprises a light source (100) adapted to provide an output light beam (230) as the optical stimulus signal. The light source (100) comprises a plurality of light emitting elements (200, 200A, 200Z) each adapted to emit a light beam (210, 210A1, 210A2, 210Z1, 210Z2) having a respective wavelength„ and a diffracting element (220). The plurality of light emitting elements (200, 200A, 200Z) are arranged that emitted light beams (210, 210A1, 210A2, 210Z1, 210Z2) impinging, on the diffracting element (220) are diffracted by the diffracting element (220) to form the output light beam (230).
Abstract:
A microdevice is provided for controlling fluid flow. The microdevice includes a substantially planar contact surface and a plurality of fluid-transporting features associated therewith. Also included is a substrate having a substantially planar contact surface and a fluid-transporting feature associated therewith. The contact surfaces are positioned in slidable and fluid-tight contact to allow for controllable formation of a plurality of different flow paths upon alignment of the substrate fluid-transporting feature with each cover plate fluid-transporting features in succession. Typically, at least one of the cover plate and substrate is comprised of a biofouling resistant polymer, and the flow paths are of different lengths. Optionally, a plurality of fluid-transporting features is associated with the substrate so that flow paths are formed as a result of a different alignment of the fluid-transporting features.
Abstract:
The fluid flow rate within a microfluidic passageway (12) of a microfabricated device is determined by measuring the time-of-flight of a heat pulse (74) coupled into the fluid (76). Since the propagation velocity of the heat trace is generally slower than the mean flow rate of the flow, additional processing provides the appropriate scaling needed to obtain an accurate fluid flow rate measurement. The scaling factor is based on the geometry of the structure (78, 80) and the thermal properties of the fluid and the materials used for the device.