USE OF LOW MOLECULAR WEIGHT AMINO ACIDS IN OPHTHALMIC COMPOSITIONS
    1.
    发明申请
    USE OF LOW MOLECULAR WEIGHT AMINO ACIDS IN OPHTHALMIC COMPOSITIONS 审中-公开
    低分子量氨基酸在眼科组合物中的应用

    公开(公告)号:WO1996003158A1

    公开(公告)日:1996-02-08

    申请号:PCT/US1995008937

    申请日:1995-07-17

    CPC classification number: A61L12/14 A01N37/44 Y10S514/912

    Abstract: The use of glycine and other low molecular weight amino acids in ophthalmic compositions (e.g., preserved saline solutions) is described. These compounds have been found to enhance the efficacy of antimicrobial preservatives. The compounds also act as chelating agents, buffers and tonicity agents.

    Abstract translation: 描述了在眼科组合物(例如,保存的盐水溶液)中使用甘氨酸和其它低分子量氨基酸。 已经发现这些化合物增强了抗微生物防腐剂的功效。 所述化合物还用作螯合剂,缓冲剂和张度剂。

    SALINE SOLUTION FOR TREATING CONTACT LENSES
    2.
    发明申请
    SALINE SOLUTION FOR TREATING CONTACT LENSES 审中-公开
    用于处理接触镜片的SALINE解决方案

    公开(公告)号:WO1996003484A1

    公开(公告)日:1996-02-08

    申请号:PCT/US1995008939

    申请日:1995-07-17

    Abstract: Improved saline solutions useful in treating contact lenses are described. Unlike prior saline solutions used for similar purposes, the present solutions do not contain conventional antimicrobial agents which are potentially toxic to ocular tissues. Rather, the solutions contain a combinaison of a borate-polyol complex, one or more anionic or nonionic surfactants, and a low molecular weight amino acid (e.g., glycine). It has been found that this combination effectively preserves the saline solutions from antimicrobial contamination, is relatively nontoxic to ocular tissues, and is compatible with oxidizing agents used in certain contact lens disinfecting systems. The combination also facilitates the cleaning of contact lenses.

    Abstract translation: 描述了用于治疗隐形眼镜的改进的盐水溶液。 不同于用于类似目的的先前的盐溶液,本溶液不含有对眼组织有潜在毒性的常规抗微生物剂。 相反,溶液含有硼酸盐 - 多元醇配合物,一种或多种阴离子或非离子表面活性剂和低分子量氨基酸(例如甘氨酸)的组合。 已经发现,这种组合有效地保留了抗菌污染的盐溶液,对眼组织相对无毒,并且与某些隐形眼镜消毒系统中使用的氧化剂相容。 该组合也有助于隐形眼镜的清洁。

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