公开(公告)号：AU2004230915A1

公开(公告)日：2004-10-28

申请号：AU2004230915

申请日：2004-04-08

Applicant: ALGORX PHARMACEUTICALS INC

Inventor： MCILVAIN SHARON ,  RAMIYA PREMCHANDRAN H ,  CARTER RICHARD B ,  ANDERSON THIMOTHY A ,  BURCH RONALD ,  CHEN WEI

IPC: A61K31/05 ,  A61K31/16 ,  A61K31/165 ,  A61K31/5415 ,  A61K31/551 ,  A61K45/06 ,  C07C51/36 ,  C07C231/02 ,  C07C233/20 ,  C07D201/00

Abstract: The present invention provides methods for synthesizing the trans isomer of capsaicin and/or capsaicin-like compounds by utilizing a process wherein the trans geometry is set from the beginning of the synthesis reaction and carried through the entire synthesis process.

公开(公告)号：AU2004230915B2

公开(公告)日：2008-08-07

申请号：AU2004230915

申请日：2004-04-08

Applicant: ALGORX PHARMACEUTICALS INC

Inventor： MCILVAIN SHARON ,  RAMIYA PREMCHANDRAN H ,  CARTER RICHARD B ,  ANDERSON THIMOTHY A ,  BURCH RONALD ,  CHEN WEI

IPC: A61K31/05 ,  A61K31/16 ,  A61K31/165 ,  A61K31/5415 ,  A61K31/551 ,  A61K45/06 ,  C07C51/36 ,  C07C231/02 ,  C07C233/20 ,  C07D201/00

Abstract: The present invention provides methods for synthesizing the trans isomer of capsaicin and/or capsaicin-like compounds by utilizing a process wherein the trans geometry is set from the beginning of the synthesis reaction and carried through the entire synthesis process.