公开(公告)号：WO2009110940A2

公开(公告)日：2009-09-11

申请号：PCT/US2008086330

申请日：2008-12-11

Applicant: AMCOL INTERNATIONAL CORP ,  DARLINGTON JR JERALD W ,  HUGHES JOHN ,  CONSTANTINIDES PANAYIOTIS P ,  FANG MINGMING ,  ST ONGE JASON HAROLD

Inventor： DARLINGTON JR JERALD W ,  HUGHES JOHN ,  CONSTANTINIDES PANAYIOTIS P ,  FANG MINGMING ,  ST ONGE JASON HAROLD

IPC: A61K33/06 ,  A01N59/00 ,  A61K33/12 ,  A61K35/02 ,  A61P31/04

CPC classification number: A61K35/02 ,  A01N59/00 ,  A61K33/06 ,  A61K33/12

Abstract: Layered phyllosilicates are useful for adsorbing and/or binding to and, thereby, inactivating viruses, bacteria and fungi. Accordingly, provided herein are methods of inactivating a virus, bacteria or fungus and methods of treating a viral, bacterial or fungal infection. Methods of delivering a therapeutic agent to a mammalian subject and methods of inactivating a virus in the gastrointestinal tract of an animal are also provided.

Abstract translation: 层状页硅酸盐可用于吸附和/或结合病毒，细菌和真菌，从而灭活病毒，细菌和真菌。 因此，本文提供了灭活病毒，细菌或真菌的方法以及治疗病毒，细菌或真菌感染的方法。 还提供了向哺乳动物受试者递送治疗剂的方法和在动物的胃肠道中灭活病毒的方法。

公开(公告)号：DE69033150D1

公开(公告)日：1999-07-15

申请号：DE69033150

申请日：1990-01-11

Applicant: AMCOL INTERNATIONAL CORP

Inventor： HUGHES JOHN

IPC: A01K1/015

Abstract: Discrete particles of a water-swellable bentonite clay effectively absorb animal dross and simultaneously agglomerate into a sufficiently large and stable mass, thereby permitting physical separation of the soiled and wetted water-swellable bentonite clay particles from discrete particles of the unsoiled and unwetted water-swellable bentonite clay. In another embodiment, the composition comprises discrete particles of a combination of water-swellable sodium bentonite clay and calcium bentonite clay that effectively absorbs animal dross and simultaneously agglomerates into a water-dispersible but physically stable mass, thereby permitting physical separation of the soiled and wetted bentonite clay particles from discrete particles of the unsoiled and unwetted water-swellable bentonite clay, and has sufficient water-dispersibility for disposal through a household plumbing or sewer conduit without clogging.

公开(公告)号：DE69033150T2

公开(公告)日：1999-10-14

申请号：DE69033150

申请日：1990-01-11

Applicant: AMCOL INTERNATIONAL CORP

Inventor： HUGHES JOHN

IPC: A01K1/015

Abstract: Discrete particles of a water-swellable bentonite clay effectively absorb animal dross and simultaneously agglomerate into a sufficiently large and stable mass, thereby permitting physical separation of the soiled and wetted water-swellable bentonite clay particles from discrete particles of the unsoiled and unwetted water-swellable bentonite clay. In another embodiment, the composition comprises discrete particles of a combination of water-swellable sodium bentonite clay and calcium bentonite clay that effectively absorbs animal dross and simultaneously agglomerates into a water-dispersible but physically stable mass, thereby permitting physical separation of the soiled and wetted bentonite clay particles from discrete particles of the unsoiled and unwetted water-swellable bentonite clay, and has sufficient water-dispersibility for disposal through a household plumbing or sewer conduit without clogging.

公开(公告)号：AU2006278591B2

公开(公告)日：2012-03-15

申请号：AU2006278591

申请日：2006-08-01

Applicant: AMCOL INTERNATIONAL CORP

Inventor： HUGHES JOHN

IPC: C12N7/04 ,  C01B33/40 ,  C09C1/42

Abstract: Layered phyllosilicates are useful for adsorbing and/or binding to and, thereby, inactivating viruses. The layered phyllosilicates can be sprayed into a person's nostrils or contained on a face mask to prevent infection; can be suspended in water for skin contact for virus inactivation; can form a portion of an HVAC filter to prevent virus transfer from room to room, e.g., in a hospital; and can be absorbed in a paper or fabric wipe for inactivating viruses on substrates, such as hospital and operating room furniture and surgical apparatus.

公开(公告)号：CA2673313A1

公开(公告)日：2008-12-04

申请号：CA2673313

申请日：2007-12-18

Applicant: AMCOL INTERNATIONAL CORP

Inventor： CONSTANTINIDES PANAYIOTIS P ,  HUGHES JOHN ,  DARLINGTON JERALD W ,  ST ONGE JASON HAROLD ,  FANG MINGMING

IPC: A61K33/06

Abstract: Layered phyllosilicates are useful for adsorbing and/or binding to and, t hereby, inactivating viruses. Accordingly, provided herein are methods of in activating a virus and methods of treating a viral infection. Methods of del ivering a therapeutic agent to a mammalian subject and methods of inactivati ng a virus in the gastrointestinal tract of an animal are also provided.

公开(公告)号：CA2713728A1

公开(公告)日：2009-09-11

申请号：CA2713728

申请日：2008-12-11

Applicant: AMCOL INTERNATIONAL CORP

Inventor： DARLINGTON JERALD W JR ,  HUGHES JOHN ,  CONSTANTINIDES PANAYIOTIS P ,  FANG MINGMING ,  ST ONGE JASON HAROLD

IPC: A61K33/06 ,  A01N59/00 ,  A61K33/12 ,  A61K35/02 ,  A61P31/04

Abstract: Layered phyllosilicates are useful for adsorbing and/or binding to and, thereby, inactivating viruses, bacteria and fungi. Accordingly, provided herein are methods of inactivating a virus, bacteria or fungus and methods of treating a viral, bacterial or fungal infection. Methods of delivering a therapeutic agent to a mammalian subject and methods of inactivating a virus in the gastrointestinal tract of an animal are also provided.

公开(公告)号：CA2621346A1

公开(公告)日：2007-02-15

申请号：CA2621346

申请日：2006-08-01

Applicant: AMCOL INTERNATIONAL CORP

Inventor： HUGHES JOHN

IPC: C12N7/04 ,  C01B33/40 ,  C09C1/42

Abstract: Layered phyllosilicates are useful for adsorbing and/or binding to and, thereby, inactivating viruses. Accordingly, provided herein is a method of inactivating a virus in the gastrointestinal tract of a mammalian subject comprising administering to said subject a composition comprising a layered phyllosilicate material in an amount effective for virus inactivation. Also provided are methods of treating a viral infection in the gastrointestinal tract of a mammalian subject. Methods of delivering a therapeutic agent to a mammalian subject and methods of inactivating a virus in waste expelled from a mammal are also provided.

公开(公告)号：AU2006278591A1

公开(公告)日：2007-02-15

申请号：AU2006278591

申请日：2006-08-01

Applicant: AMCOL INTERNATIONAL CORP

Inventor： HUGHES JOHN

IPC: C12N7/04 ,  C01B33/40 ,  C09C1/42

Abstract: Layered phyllosilicates are useful for adsorbing and/or binding to and, thereby, inactivating viruses. Accordingly, provided herein is a method of inactivating a virus in the gastrointestinal tract of a mammalian subject comprising administering to said subject a composition comprising a layered phyllosilicate material in an amount effective for virus inactivation. Also provided are methods of treating a viral infection in the gastrointestinal tract of a mammalian subject. Methods of delivering a therapeutic agent to a mammalian subject and methods of inactivating a virus in waste expelled from a mammal are also provided.