公开(公告)号：WO2022192414A2

公开(公告)日：2022-09-15

申请号：PCT/US2022/019573

申请日：2022-03-09

Applicant: AMGEN INC.

Inventor： CAILLE, Sebastien ,  MURRAY, James ,  QUASDORF, Kyle ,  NGUYEN, Hannah ,  SILVA ELIPE, Maria Victoria ,  ERICSON, Ari Elizabeth

IPC: C07C201/10 ,  C07C205/12 ,  C07C201/08

Abstract: Provided herein are synthetic methods for the preparation of intermediates that are utilized in the synthesis of omecamtiv mecarbil dihydrochloride.

公开(公告)号：EP4305018A2

公开(公告)日：2024-01-17

申请号：EP22712763.6

申请日：2022-03-09

Applicant: Amgen Inc.

Inventor： CAILLE, Sebastien ,  MURRAY, James ,  QUASDORF, Kyle ,  NGUYEN, Hannah ,  SILVA ELIPE, Maria Victoria ,  ERICSON, Ari Elizabeth

IPC: C07C201/10 ,  C07C205/12